{"id":14458,"date":"2026-11-02T16:00:00","date_gmt":"2026-11-02T16:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=14458"},"modified":"2026-11-05T17:10:15","modified_gmt":"2026-11-05T17:10:15","slug":"homa-beta","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/de\/biomarkers\/homa-beta\/","title":{"rendered":"HOMA-beta"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. 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Lees waar een lage of hoge waarde op kan wijzen.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-31\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-beta\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-beta\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-beta\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/\"},{\"@type\":\"CreativeWork\",\"name\":\"MedlinePlus, U.S. National Library of Medicine. Insulin in Blood. Geraadpleegd op 31 oktober 2026.\",\"url\":\"https:\/\/medlineplus.gov\/lab-tests\/insulin-in-blood\/\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-beta\/#biomarker\",\"name\":\"HOMA-beta\",\"alternateName\":[\"HOMA-Beta\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/de\/\">Home<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/\">Biomarker<\/a> \u203a <span>HOMA-beta<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">HOMA-beta: wie gut Ihre Betazellen Insulin bilden<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">HOMA-beta ist eine berechnete Sch\u00e4tzung, wie gut die Zellen in Ihrer Bauchspeicheldr\u00fcse Insulin bilden, auf Grundlage Ihrer N\u00fcchternglukose und Ihres Insulins. Ein niedriger Wert kann auf ein Defizit in dieser Funktion hinweisen. Ein hoher Wert kann auf eine Bauchspeicheldr\u00fcse hinweisen, die zus\u00e4tzlich Insulin bildet, weil Ihr K\u00f6rper weniger gut auf Insulin reagiert.<sup>[1, 2]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">Auf dieser Seite lesen Sie, was HOMA-beta ist, was die Leitlinien \u00fcber einen zu niedrigen oder zu hohen Wert sagen, was Ihren Wert beeinflusst und welche Werte Sie am besten daneben betrachten.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Auch: HOMA-B, Betazellfunktion nach HOMA. Im Labor: entf\u00e4llt.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Aktualisiert am 31. Oktober 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">Auf dieser Seite<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">Kurz gefasst<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-homa-beta\">Was ist HOMA-beta?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Warum HOMA-beta wichtig ist<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">Was Ihr HOMA-beta-Wert aussagt<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">Was Ihren HOMA-beta-Wert beeinflusst<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Welche BioProfile-Pakete HOMA-beta messen<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Werte, die dazugeh\u00f6ren<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">Wie diese Seite entstanden ist<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Quellen<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">Kurz gefasst<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>HOMA-beta sch\u00e4tzt die Funktion Ihrer Betazellen aus Ihrer N\u00fcchternglukose und Ihrem Insulin.<sup>[1]<\/sup><\/li>\n\n\n<li>Insulin ist ein Hormon aus Ihrer Bauchspeicheldr\u00fcse, das der Glukose hilft, aus Ihrem Blut in Ihre Zellen zu gelangen.<sup>[2]<\/sup><\/li>\n\n\n<li>Ein niedriger Wert kann auf ein Defizit in der Funktion Ihrer Betazellen hinweisen.<sup>[1]<\/sup><\/li>\n\n\n<li>Die Sch\u00e4tzung hat eine geringe Pr\u00e4zision, und ein Arzt betrachtet das Resultat zusammen mit anderen Ergebnissen.<sup>[1, 2]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-homa-beta\">Was ist HOMA-beta?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">HOMA steht f\u00fcr homeostasis model assessment. Es ist ein Computermodell, das vorhersagt, welche N\u00fcchternwerte f\u00fcr Glukose und Insulin zu einer bestimmten Funktion der Betazellen geh\u00f6ren und dazu, wie gut der K\u00f6rper auf Insulin reagiert. Ihre eigenen N\u00fcchternwerte werden mit diesen Vorhersagen verglichen.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Insulin ist ein Hormon, das Ihre Bauchspeicheldr\u00fcse bildet. Nach dem Essen steigt Ihr Blutzucker, und das ist f\u00fcr Ihre Bauchspeicheldr\u00fcse das Signal, mehr Insulin abzugeben. Insulin hilft der Glukose, aus Ihrem Blut in Ihre Zellen zu gelangen, wo sie Energie liefert. Sinkt Ihr Blutzucker, gibt Ihre Bauchspeicheldr\u00fcse weniger Insulin ab.<sup>[2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HOMA-beta ist der Teil des Modells, der die Funktion der Betazellen sch\u00e4tzt. In der urspr\u00fcnglichen Studie hing diese Sch\u00e4tzung mit einer Messung per Clamp-Test (Rs = 0,61) und mit einem intraven\u00f6sen Glukosetoleranztest (Rs = 0,64) zusammen.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Warum HOMA-beta wichtig ist<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Bildet Ihre Bauchspeicheldr\u00fcse zu wenig Insulin oder reagiert Ihr K\u00f6rper weniger gut auf Insulin, kann die Glukose nicht gut in Ihre Zellen gelangen. Die Glukose sammelt sich dann in Ihrem Blut an, und Ihr Blutzucker wird zu hoch.<sup>[2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Reagiert Ihr K\u00f6rper schlechter auf Insulin, kann Ihre Bauchspeicheldr\u00fcse mehr Insulin bilden. So bleibt Ihr Blutzucker eine Zeit lang in einem guten Referenzbereich. Mit der Zeit kann Ihre Bauchspeicheldr\u00fcse vielleicht nicht mehr genug Insulin bilden, und Ihr Blutzucker kann zu hoch werden.<sup>[2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HOMA-beta hilft so zu erkennen, welcher Teil eines erh\u00f6hten N\u00fcchternblutzuckers mit der Funktion Ihrer Betazellen zusammenh\u00e4ngt und welcher Teil damit, wie Ihr K\u00f6rper auf Insulin reagiert.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">Was Ihr HOMA-beta-Wert aussagt<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Das HOMA-Modell von Matthews und Kollegen<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Ergebnis<\/th><th>Worauf es hinweisen kann<\/th><th>F\u00fcr wen<\/th><\/tr><\/thead><tbody><tr><td>Niedrige gesch\u00e4tzte Betazellfunktion<sup>[1]<\/sup><\/td><td>Ein Defizit in der Funktion der Betazellen, als Beitrag zu einem erh\u00f6hten N\u00fcchternblutzucker<\/td><td>Menschen, bei denen N\u00fcchternglukose und Insulin gemessen wurden<\/td><\/tr><tr><td>Jedes Resultat<sup>[1]<\/sup><\/td><td>Eine Sch\u00e4tzung mit geringer Pr\u00e4zision: Der Variationskoeffizient f\u00fcr das Betazelldefizit betr\u00e4gt 32%<\/td><td>Alle, bei denen HOMA-beta berechnet wird<\/td><\/tr><tr><td>Kein fester Grenzwert<sup>[1]<\/sup><\/td><td>Das Modell vergleicht Ihre N\u00fcchternwerte mit seinen eigenen Vorhersagen<\/td><td>Alle, bei denen HOMA-beta berechnet wird<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Quelle: Matthews und Kollegen, der urspr\u00fcngliche Artikel \u00fcber das HOMA-Modell beim Menschen. Der Artikel nennt keine Grenzwerte f\u00fcr HOMA-beta.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">HOMA-beta zu hoch<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ein hoher HOMA-beta-Wert kann auf eine Bauchspeicheldr\u00fcse hinweisen, die im Verh\u00e4ltnis zu Ihrer N\u00fcchternglukose viel Insulin bildet. Laut MedlinePlus kann Ihre Bauchspeicheldr\u00fcse mehr Insulin bilden, wenn Ihr K\u00f6rper weniger gut auf Insulin reagiert. Zu viel Insulin im Blut kann Ihren Blutzucker zu niedrig werden lassen.<sup>[1, 2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">HOMA-beta zu niedrig<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ein niedriger HOMA-beta-Wert kann auf ein Defizit in der Funktion Ihrer Betazellen hinweisen. Im HOMA-Modell ist das einer der zwei Beitr\u00e4ge zu einem erh\u00f6hten N\u00fcchternblutzucker. Der andere ist, wie gut Ihr K\u00f6rper auf Insulin reagiert. Bildet Ihre Bauchspeicheldr\u00fcse zu wenig Insulin, kann Ihr Blutzucker zu hoch werden.<sup>[1, 2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile arbeitet an eigenen Zonen pro Wert, von Risiko bis optimal. Ein Arzt pr\u00fcft diese Zonen, bevor sie in Ihrem Ergebnis erscheinen.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">Was Ihr HOMA-beta beeinflusst<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Essen und n\u00fcchtern sein<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Nach dem Essen steigen Ihr Blutzucker und Ihr Insulin gemeinsam. HOMA-beta geht von N\u00fcchternwerten aus. F\u00fcr einen Insulintest m\u00fcssen Sie meist 8 bis 12 Stunden n\u00fcchtern sein: nichts essen und nichts trinken.<sup>[2, 1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Biotin als Nahrungserg\u00e4nzung<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Wenn Sie Biotin oder ein Nahrungserg\u00e4nzungsmittel mit Biotin einnehmen, m\u00fcssen Sie laut MedlinePlus mindestens einen Tag vor Ihrem Test damit aufh\u00f6ren.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Insulinmedikamente<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Manche Menschen, die Insulin anwenden, bilden Antik\u00f6rper gegen Insulin. Diese Antik\u00f6rper k\u00f6nnen den Insulintest st\u00f6ren und zu einem falschen Ergebnis f\u00fchren. Sagen Sie Ihrem Arzt, ob Sie Insulin anwenden, aber setzen Sie nie ein Medikament ab, ohne vorher mit Ihrem Arzt zu sprechen.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Wie Ihr K\u00f6rper auf Insulin reagiert<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Reagiert Ihr K\u00f6rper schlechter auf Insulin, kann Ihre Bauchspeicheldr\u00fcse mehr Insulin bilden, um Glukose in Ihre Zellen zu bringen. Diese Wahrscheinlichkeit ist laut MedlinePlus gr\u00f6\u00dfer, wenn Sie eine Erkrankung des Herzens haben, eine Erkrankung der Eierst\u00f6cke mit vielen Zysten oder eine dunkle, dicke, samtartige Haut am Nacken oder in den Achseln.<sup>[2]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Welche BioProfile-Pakete HOMA-beta messen<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">HOMA-beta ist in BioProfile 121 und 150 enthalten.<sup>[3]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/de\/blutuntersuchung\/\">Die Pakete ansehen<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Werte, die dazugeh\u00f6ren<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/hba1c\/\">HbA1c<\/a>: zeigt die durchschnittliche Menge an Glukose in Ihrem Blut \u00fcber einige Monate, neben der n\u00fcchternen Momentaufnahme von HOMA-beta.<sup>[2]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/triglyceride\/\">Triglyceride<\/a>: die Fette in Ihrem Blut, ein zweiter Blick auf Ihren Stoffwechsel neben HOMA-beta.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/harnsaeure\/\">Harns\u00e4ure<\/a>: ein Abfallstoff in Ihrem Blut, den Sie zusammen mit Ihren Zuckerwerten betrachten, f\u00fcr ein breiteres Bild Ihres Stoffwechsels.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/ketone-im-urin\/\">Ketone (Urin)<\/a>: ein Stoffwechselwert in Ihrem Urin, den Sie zusammen mit Ihrem Blutzucker und Ihrem Insulin betrachten.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/de\/biomarkers\/glukose-urin\/\">Glukose (Urin)<\/a>: Zucker in Ihrem Urin, ein zweiter Blick auf Ihren Zuckerhaushalt neben den Werten in Ihrem Blut.<\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">Wie diese Seite entstanden ist<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Die BioProfile-Redaktion hat diese Seite am 31. Oktober 2026 auf Grundlage der unten genannten Quellen geschrieben, die wir am 31. Oktober 2026 gelesen haben. Jede Zahl auf dieser Seite steht in einer dieser Quellen, mit der Nummer der jeweiligen Quelle. Eine Fachperson pr\u00fcft diese Seite noch; nach dieser Pr\u00fcfung stehen der Name der Fachperson und das Datum der Pr\u00fcfung oben auf der Seite. Diese Seite dient der Erkl\u00e4rung und stellt keine Diagnose. Besprechen Sie einen abweichenden Wert mit Ihrer Hausarztpraxis.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Quellen<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/<\/a><\/li>\n\n\n<li>MedlinePlus, U.S. National Library of Medicine. Insulin in Blood. Abgerufen am 31. Oktober 2026. <a href=\"https:\/\/medlineplus.gov\/lab-tests\/insulin-in-blood\/\" target=\"_blank\" rel=\"noopener\">https:\/\/medlineplus.gov\/lab-tests\/insulin-in-blood\/<\/a><\/li>\n\n\n<li>BioProfile, die Pakete der Blutuntersuchung und die Werte in jedem Paket. <a href=\"https:\/\/bioprofile.com\/de\/blutuntersuchung\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/de\/blutuntersuchung\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Home \u203a Biomarker \u203a HOMA-beta HOMA-beta: wie gut Ihre Betazellen Insulin bilden HOMA-beta ist eine berechnete Sch\u00e4tzung, wie gut die Zellen in Ihrer Bauchspeicheldr\u00fcse Insulin bilden, auf Grundlage Ihrer N\u00fcchternglukose und Ihres Insulins. Ein niedriger Wert kann auf ein Defizit in dieser Funktion hinweisen. Ein hoher Wert kann auf eine Bauchspeicheldr\u00fcse hinweisen, die zus\u00e4tzlich Insulin [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6596,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"HOMA-beta: Funktion Ihrer Betazellen | BioProfile","_yoast_wpseo_metadesc":"HOMA-beta sch\u00e4tzt aus Ihrer N\u00fcchternglukose und Ihrem Insulin, wie gut Ihre Betazellen Insulin bilden. 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