{"id":10219,"date":"2026-10-10T15:00:00","date_gmt":"2026-10-10T15:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=10219"},"modified":"2026-10-10T15:42:07","modified_gmt":"2026-10-10T15:42:07","slug":"alt","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/en\/biomarkers\/alt\/","title":{"rendered":"ALT"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. 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Lees wat een te lage of te hoge waarde kan aangeven en wat je uitslag be\u00efnvloedt.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-08\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/alat\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/alat\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/alat\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"MedlinePlus, U.S. National Library of Medicine. ALT Blood Test. Geraadpleegd op 8 oktober 2026.\",\"url\":\"https:\/\/medlineplus.gov\/lab-tests\/alt-blood-test\/\"},{\"@type\":\"CreativeWork\",\"name\":\"Labplusarts, het laboratorium waarmee BioProfile werkt: referentiewaarde bij de bepaling alat (GPT), 0 tot 45 u\/l. Lijst van 24 september 2026.\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/alat\/#biomarker\",\"name\":\"ALAT\",\"alternateName\":[\"ALT\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/en\/\">Home<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/\">Biomarkers<\/a> \u203a <span>ALT<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">ALT: what this liver marker tells you<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">ALT is an enzyme found mainly in your liver. A high level can point to liver damage. A low level is unusual and can be a reason for your doctor to look into it further.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">On this page you can read what ALT is, what the guidelines say about a value that is too low or too high, what affects your value and which other values are best to look at alongside it.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Also called: alanine aminotransferase, alanine transaminase, SGPT. At the lab: GPT.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Updated on 8 October 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">On this page<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">In short<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-alat\">What is ALT?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Why this value matters<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">What your ALT level tells you<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">What affects your ALT<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Which BioProfile packages measure ALT<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Related values<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">How this page was made<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Sources<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">In short<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>ALT is an enzyme found mainly in your liver, and normally only small amounts of it get into your blood.<sup>[1]<\/sup><\/li>\n\n\n<li>When liver cells are damaged, they release ALT into your blood, so a high level can point to liver damage.<sup>[1]<\/sup><\/li>\n\n\n<li>A high level does not always mean there is a condition that needs care, because age, weight, medicines and hard exercise also play a part.<sup>[1]<\/sup><\/li>\n\n\n<li>Your doctor usually compares your ALT with other liver tests, such as AST.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-alat\">What is ALT?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ALT stands for alanine aminotransferase. It is an enzyme: a protein that speeds up certain chemical reactions in your body. It is found mainly in your liver.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Normally there is little ALT in your blood. If liver cells are damaged, ALT is released into your bloodstream. Because ALT is found mainly in the liver, this test looks fairly specifically at liver damage.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The test is usually done together with other liver tests. These measure various proteins, substances and enzymes that show how well your liver is working.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Why this value matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">An ALT test is often part of a routine blood check to see how healthy your liver is. The test can also help detect or monitor liver problems.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some liver conditions already cause a high ALT before you notice anything. That is why the test can help to spot such problems early.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A doctor may also order the test if you have symptoms such as nausea, poor appetite, tiredness, yellow skin or yellow eyes, dark urine or a lot of itching. Or if you have a higher risk, for example because of liver conditions in your family, problematic alcohol use, being very overweight or certain medicines.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ALT can help tell the difference between sudden and long-term liver problems. How high your ALT is does not, however, tell you how much damage your liver has.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">What your ALT value tells you<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">The lab's reference range<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Labplusarts, the lab BioProfile works with, uses a reference value of 0 to 45 u\/l for ALT (GPT). The lab calls a level between those limits normal.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The Labplusarts guideline in a table<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Value<\/th><th>What it can mean<\/th><th>Who it is for<\/th><\/tr><\/thead><tbody><tr><td>0 to 45 u\/l<sup>[2]<\/sup><\/td><td>The lab calls this normal<\/td><td>ALT (GPT) measurements at this lab<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Source: Labplusarts, the lab BioProfile works with. Reference value for ALT (GPT) measured in this lab.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ALT too low<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A lower ALT than usual is not common. Your doctor may then do more tests, because it can point to a vitamin B6 deficiency or a long-term kidney condition.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ALT too high<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A higher ALT than usual can point to liver damage. This can be caused by inflammation of the liver, other liver conditions, too little blood supply to the liver, certain medicines such as cholesterol medicines or painkillers, or toxic substances. A high level does not always mean there is a condition that needs care. Talk to your doctor about what your result means for you.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile is working on its own zones for each value, from risk to optimal. A doctor reviews those zones before they appear in your result.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">What affects your ALT<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Medicines and supplements<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Certain medicines and dietary supplements can affect your result. Tell your doctor what you take. Never stop a medicine on your own, only when your doctor tells you to.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Hard exercise<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Heavy physical exertion can affect your ALT.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Your body<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Your age, sex and weight also play a part. Your ALT can also vary depending on where you are in your menstrual cycle.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Fasting<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ALT is usually measured together with other blood tests. For these, you often need to fast for a few hours. Your healthcare provider will tell you if there are any special instructions.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Which BioProfile packages measure ALT<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ALT is included in BioProfile 77, 98, 121 and 150.<sup>[3]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\">View the packages<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Values that go with it<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><strong>ALP<\/strong>: ALT is usually measured together with other liver tests, and your doctor compares those results with each other.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>Bilirubin, total<\/strong>: liver tests measure different substances that together show how well your liver is working.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>GGT<\/strong>: your doctor looks at your ALT alongside the results of other liver tests to judge whether further tests are needed.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>AST<\/strong>: another liver enzyme that is usually measured together with ALT, while ALT looks more specifically at the liver.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/albumin\/\">Albumin<\/a>: liver tests also measure proteins, and together with ALT they give a picture of how your liver is working.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">How this page was made<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The BioProfile editorial team wrote this page on 8 October 2026 from the sources below, which we read on 8 October 2026. Every number on this page appears in one of those sources, with the number of that source next to it. An expert will still review this page; after that review, the expert's name and the date of the review will appear at the top. This page offers explanation, not a diagnosis. Discuss an abnormal level with your GP.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Sources<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>MedlinePlus, U.S. National Library of Medicine. ALT Blood Test. Accessed 8 October 2026. <a href=\"https:\/\/medlineplus.gov\/lab-tests\/alt-blood-test\/\" target=\"_blank\" rel=\"noopener\">https:\/\/medlineplus.gov\/lab-tests\/alt-blood-test\/<\/a><\/li>\n\n\n<li>Labplusarts, the laboratory BioProfile works with: reference value for the ALT (GPT) test, 0 to 45 u\/l. List dated 24 September 2026.<\/li>\n\n\n<li>BioProfile, the blood test packages and the values in each package. <a href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/en\/blood-testing\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Home \u203a Biomarkers \u203a ALT ALT: what this liver marker tells you ALT is an enzyme found mainly in your liver. A high level can point to liver damage. A low level is unusual and can be a reason for your doctor to look into it further.[1] On this page you can read what ALT [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6592,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"ALT in your blood: what your level tells you | BioProfile","_yoast_wpseo_metadesc":"ALT is an enzyme found mainly in your liver. 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