{"id":15078,"date":"2026-10-18T15:00:00","date_gmt":"2026-10-18T15:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=15078"},"modified":"2026-11-05T02:39:21","modified_gmt":"2026-11-05T02:39:21","slug":"fib-4-index","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/","title":{"rendered":"FIB-4 index"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. Core wraps the link in .wp-block-button,\n     which is shrink-to-fit, so widening only the link leaves it content-sized. *\/\n  .bp-adv .wp-block-button { width: 100%; }\n  .bp-adv .wp-block-button__link { padding: 15px 24px; width: 100%; }\n  .bp-adv .bp-adv-numcard .wp-block-columns { gap: var(--bp-s-4); }\n}\n@media (prefers-reduced-motion: reduce) { .bp-adv * { transition-duration: 0ms; } }\n\n\/* --- the author portrait -----------------------------------------------------\n   Two shapes, because there are two ways a portrait reaches the box.\n   1. `bp-adv-avatar--photo` turns the dashed FOTO circle into a photo frame when\n      an editor drops an inline image into the placeholder paragraph.\n   2. `bp-adv-avatar-img` is the shipped path: a REAL core\/image block, so the\n      picture is click-editable and \"Vervangen\" works. The grid-row span is the\n      load-bearing line. The paragraph avatar carries `grid-row: 1 \/ span 3` in\n      the 62px + 1fr card grid; a figure that does not carry it drops the name\n      under the photo instead of beside it. Found by screenshot on 2026-07-30\n      and fixed on the live page with exactly this rule. ---------------------- *\/\n.bp-adv-avatar--photo{border-style:solid;padding:0;overflow:hidden;background:#fff}\n.bp-adv-avatar--photo img{width:100%;height:100%;object-fit:cover;object-position:center;border-radius:50%;display:block}\n.bp-adv-author .bp-adv-avatar-img{grid-row:1 \/ span 3;flex:0 0 auto;margin:0;width:62px;height:62px}\n.bp-adv-author .bp-adv-avatar-img img{width:62px;height:62px;object-fit:cover;object-position:center;border-radius:50%;border:2px solid var(--bp-olive);display:block}\n\n\/* --- the advertorial's own chrome (synced patterns 4822 and 4823) ------------\n   Deliberately NOT scoped to `.bp-adv`: the header and footer are siblings of\n   the article, outside that container, because canvas gives the page no chrome\n   of its own. A <style> element styles the whole document wherever it sits, so\n   these rules reach the two pattern references either side of the article. --- *\/\n.bp-adv-sitehead{background:#fff;border-bottom:1px solid #e6ece9;padding:12px 24px;margin:0}\n.bp-adv-sitehead .bp-adv-sitehead-logo{margin:0 auto;max-width:1120px}\n.bp-adv-sitehead img{height:30px;width:auto;display:block}\n.bp-adv-sitefoot{background:#f4f1ec;border-top:1px solid #e6ece9;padding:28px 24px;margin-top:44px}\n.bp-adv-sitefoot p{max-width:1120px;margin:0 auto;font-size:13px;line-height:1.8;color:#4d5f5d;text-align:center}\n.bp-adv-sitefoot a{color:#005859;text-decoration:underline}\n.bp-adv-sitefoot .bp-adv-sitefoot-legal{margin-top:6px}\n.bp-biomarker sup{font-size:.72em;line-height:0;vertical-align:super;color:var(--bp-foot);margin-left:1px}\n.bp-biomarker .bp-bm-crumbs{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker .bp-bm-crumbs a,.bp-biomarker .bp-bm-toc a,.bp-biomarker .bp-bm-src a,.bp-biomarker .bp-bm-rows a,\n.bp-biomarker .bp-bm-related a{display:inline-flex;align-items:center;min-height:44px}\n.bp-biomarker .bp-bm-names{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-4)}\n.bp-biomarker .bp-bm-toc ul{margin-block:0;padding-left:var(--bp-s-5)}\n.bp-biomarker .bp-bm-toc li{margin:0 0 var(--bp-s-1)}\n.bp-biomarker .bp-bm-src li{overflow-wrap:anywhere}\n.bp-biomarker .bp-bm-rows{list-style:none;padding-left:0}\n.bp-biomarker .bp-bm-rows li{padding-block:6px;border-bottom:1px solid var(--bp-sand)}\n.bp-biomarker .bp-bm-rows li:last-child{border-bottom:0}\n.bp-biomarker .bp-bm-rows a{font-weight:700}\n.bp-biomarker .bp-bm-count{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker figure.wp-block-table{margin-block:var(--bp-s-4) var(--bp-s-2);margin-inline:auto;overflow:visible}\n.bp-biomarker figure.wp-block-table table{table-layout:fixed;width:100%;border-collapse:collapse;\n font-size:var(--bp-fs-small);line-height:1.45;background:var(--bp-white)}\n.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{border:1px solid var(--bp-sand);\n padding:8px 10px;vertical-align:top;text-align:left;hyphens:auto;-webkit-hyphens:auto;overflow-wrap:break-word}\n.bp-biomarker figure.wp-block-table thead th{background:var(--bp-teal);color:var(--bp-white);font-weight:600}\n.bp-biomarker .bp-bm-caption{font-size:var(--bp-fs-foot);color:var(--bp-foot);margin-block:0 var(--bp-s-5)}\n@media (max-width:480px){.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{\n padding:6px 6px;font-size:13.5px}}<\/style>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/fib-4\/#article\",\"headline\":\"FIB-4-index: wat je score zegt over je lever\",\"description\":\"De FIB-4-index schat met gewone bloedwaarden in hoeveel littekenweefsel er in je lever kan zitten. Lees wat een lage of hoge score kan aangeven.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-16\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/fib-4\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/fib-4\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/fib-4\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV\/HCV coinfection. Hepatology. 2006;43(6):1317-25.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16729309\/\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/fib-4\/#biomarker\",\"name\":\"FIB-4-index\",\"alternateName\":[\"FIB-4 index\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/en\/\">Home<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/\">Biomarkers<\/a> \u203a <span>FIB-4 index<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">FIB-4 index: what your score says about your liver<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">In the study in which the FIB-4 index was developed, examining a small piece of liver tissue could be skipped for 71% of the group in which the score was tested. These were people with two long-term viral conditions, one of which affects the liver.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">On this page you can read what the FIB-4 index is, what the guidelines say about a value that is too low or too high, what affects your value and which values are best to look at alongside it.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Also known as: FIB-4 score, Fibrosis-4 score. At the lab: n\/a.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Updated on 16 October 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">On this page<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">In short<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-fib-4\">What is the FIB-4 index?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Why this score matters<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">What your FIB-4 index value tells you<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">What affects your FIB-4 index<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Which BioProfile packages measure the FIB-4 index<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Related values<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">How this page was made<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Sources<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">In short<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>The FIB-4 index uses ordinary blood values to estimate whether there may be advanced scar tissue in your liver.<sup>[1]<\/sup><\/li>\n\n\n<li>A score below 1.45 can indicate that there is no advanced scar tissue.<sup>[1]<\/sup><\/li>\n\n\n<li>A score above 3.25 can point to advanced scar tissue.<sup>[1]<\/sup><\/li>\n\n\n<li>These cut-offs come from a study of people with two long-term viral conditions, one of which affects the liver.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-fib-4\">What is the FIB-4 index?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The FIB-4 index is a calculated score that estimates how much scar tissue there may be in your liver. It is not a separate measurement in your blood. The score is calculated from ordinary blood values that are often already measured.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The calculation uses your age, your AST, your ALT and the number of platelets in your blood. A higher age and a higher AST make the score higher. More platelets and a higher ALT make the score lower.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A low score can indicate that there is little scar tissue in the liver. A high score can point to more scar tissue. The index was designed as a simple test without a procedure. This way, the score can reduce the need to examine a small piece of liver tissue.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Why this score matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Examining a small piece of liver tissue used to be the gold standard for determining how severe a liver condition is. Such a procedure carries risks. That is why tests without a procedure are being used more and more.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Many other scores use tests that are not available everywhere. The researchers wanted a score that uses only routine blood values.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In the study, the two cut-offs together correctly classified 87% of the 198 people with a score below 1.45 or above 3.25.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">What your FIB-4 index value tells you<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">What the study by Sterling and colleagues says<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Score<\/th><th>What it can indicate<\/th><th>Who it is for<\/th><\/tr><\/thead><tbody><tr><td>Below 1.45<sup>[1]<\/sup><\/td><td>Can indicate that there is no advanced scar tissue. Of the people with this score, 90% had no advanced scar tissue.<\/td><td>People with two long-term viral conditions, one of which affects the liver<\/td><\/tr><tr><td>Between 1.45 and 3.25<sup>[1]<\/sup><\/td><td>Falls between the two cut-offs. The study did not place these scores in a group.<\/td><td>People with two long-term viral conditions, one of which affects the liver<\/td><\/tr><tr><td>Above 3.25<sup>[1]<\/sup><\/td><td>Can point to advanced scar tissue. Of the people with this score, 65% had advanced scar tissue.<\/td><td>People with two long-term viral conditions, one of which affects the liver<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Source: Sterling and colleagues, Hepatology 2006. A study of 832 people with two long-term viral conditions, one of which affects the liver.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">FIB-4 index too high<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A score above 3.25 can point to advanced scar tissue in the liver. In the study, 97% of the people without advanced scar tissue stayed below that cut-off.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile is working on its own zones for each value, from risk to optimal. A doctor reviews those zones before they appear in your result.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">What affects your FIB-4 index<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Your age<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">In the formula, your age in years is multiplied by your AST. So if your other values stay the same, the score rises as the years go by.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Your AST<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">AST sits above the line of the fraction in the formula. This means every rise in your AST feeds straight into the score.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Your platelets<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Your platelet count sits below the line of the fraction. Fewer platelets make the score higher. In the study, the platelet count was clearly linked to scar tissue in the liver.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Your ALT<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Your ALT counts through its square root, below the line of the fraction. This means a change in your ALT has a weaker effect than the same change in your AST.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Which BioProfile packages measure the FIB-4 index<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The FIB-4 index is included in BioProfile 77, 87, 121 and 150.<sup>[2]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\">View the packages<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Values that go with it<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/alkaline-phosphatase\/\">ALP<\/a>: another liver value to look at alongside the FIB-4 index for a broader picture of your liver.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/alt\/\">ALT<\/a>: one of the four values used to calculate the FIB-4 index.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/total-bilirubin\/\">Bilirubin, total<\/a>: another liver value to look at alongside the FIB-4 index for a broader picture of your liver.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/ggt\/\">GGT<\/a>: another liver value to look at alongside the FIB-4 index for a broader picture of your liver.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/ast\/\">AST<\/a>: one of the four values used to calculate the FIB-4 index, and the value that pushes the score up the most.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">How this page was made<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The BioProfile editorial team wrote this page on 16 October 2026 from the sources below, which we read on 16 October 2026. Every number on this page comes from one of those sources, with that source's number beside it. An expert has yet to review this page; once the review is done, the expert's name and the date of the review will appear at the top. This page explains and does not diagnose. Discuss an abnormal value with your GP.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Sources<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV\/HCV coinfection. Hepatology. 2006;43(6):1317-25. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16729309\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16729309\/<\/a><\/li>\n\n\n<li>BioProfile, the blood test packages and the values in each package. <a href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/en\/blood-testing\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Home \u203a Biomarkers \u203a FIB-4 index FIB-4 index: what your score says about your liver In the study in which the FIB-4 index was developed, examining a small piece of liver tissue could be skipped for 71% of the group in which the score was tested. These were people with two long-term viral conditions, one [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6592,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"FIB-4 index: what does your score say about your liver? | BioProfile","_yoast_wpseo_metadesc":"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-15078","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>FIB-4 index: what does your score say about your liver? | BioProfile<\/title>\n<meta name=\"description\" content=\"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FIB-4 index: what does your score say about your liver? | BioProfile\" \/>\n<meta property=\"og:description\" content=\"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/\" \/>\n<meta property=\"og:site_name\" content=\"Bioprofile.com\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-05T02:39:21+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/fib-4-index\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/fib-4-index\\\/\",\"name\":\"FIB-4 index: what does your score say about your liver? | BioProfile\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#website\"},\"datePublished\":\"2026-10-18T15:00:00+00:00\",\"dateModified\":\"2026-11-05T02:39:21+00:00\",\"description\":\"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/fib-4-index\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/fib-4-index\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/fib-4-index\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/home-2026\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Biomarkers\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"FIB-4 index\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/\",\"name\":\"Bioprofile.com\",\"description\":\"Live longer, stay younger\",\"publisher\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#organization\",\"name\":\"Bioprofile.com\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"contentUrl\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"width\":173,\"height\":48,\"caption\":\"Bioprofile.com\"},\"image\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"FIB-4 index: what does your score say about your liver? | BioProfile","description":"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/","og_locale":"en_US","og_type":"article","og_title":"FIB-4 index: what does your score say about your liver? | BioProfile","og_description":"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.","og_url":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/","og_site_name":"Bioprofile.com","article_modified_time":"2026-11-05T02:39:21+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/","url":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/","name":"FIB-4 index: what does your score say about your liver? | BioProfile","isPartOf":{"@id":"https:\/\/bioprofile.com\/en\/#website"},"datePublished":"2026-10-18T15:00:00+00:00","dateModified":"2026-11-05T02:39:21+00:00","description":"The FIB-4 index uses ordinary blood values to estimate how much scar tissue there may be in your liver. Read what a low or high score can indicate.","breadcrumb":{"@id":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/bioprofile.com\/en\/biomarkers\/fib-4-index\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/bioprofile.com\/en\/home-2026\/"},{"@type":"ListItem","position":2,"name":"Biomarkers","item":"https:\/\/bioprofile.com\/en\/biomarkers\/"},{"@type":"ListItem","position":3,"name":"FIB-4 index"}]},{"@type":"WebSite","@id":"https:\/\/bioprofile.com\/en\/#website","url":"https:\/\/bioprofile.com\/en\/","name":"Bioprofile.com","description":"Live longer, stay younger","publisher":{"@id":"https:\/\/bioprofile.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/bioprofile.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/bioprofile.com\/en\/#organization","name":"Bioprofile.com","url":"https:\/\/bioprofile.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/bioprofile.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","contentUrl":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","width":173,"height":48,"caption":"Bioprofile.com"},"image":{"@id":"https:\/\/bioprofile.com\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/comments?post=15078"}],"version-history":[{"count":1,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15078\/revisions"}],"predecessor-version":[{"id":15079,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15078\/revisions\/15079"}],"up":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/6592"}],"wp:attachment":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/media?parent=15078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}