{"id":15105,"date":"2026-11-05T06:00:00","date_gmt":"2026-11-05T06:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=15105"},"modified":"2026-11-05T06:16:42","modified_gmt":"2026-11-05T06:16:42","slug":"shbg","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/","title":{"rendered":"SHBG"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. Core wraps the link in .wp-block-button,\n     which is shrink-to-fit, so widening only the link leaves it content-sized. *\/\n  .bp-adv .wp-block-button { width: 100%; }\n  .bp-adv .wp-block-button__link { padding: 15px 24px; width: 100%; }\n  .bp-adv .bp-adv-numcard .wp-block-columns { gap: var(--bp-s-4); }\n}\n@media (prefers-reduced-motion: reduce) { .bp-adv * { transition-duration: 0ms; } }\n\n\/* --- the author portrait -----------------------------------------------------\n   Two shapes, because there are two ways a portrait reaches the box.\n   1. `bp-adv-avatar--photo` turns the dashed FOTO circle into a photo frame when\n      an editor drops an inline image into the placeholder paragraph.\n   2. `bp-adv-avatar-img` is the shipped path: a REAL core\/image block, so the\n      picture is click-editable and \"Vervangen\" works. The grid-row span is the\n      load-bearing line. The paragraph avatar carries `grid-row: 1 \/ span 3` in\n      the 62px + 1fr card grid; a figure that does not carry it drops the name\n      under the photo instead of beside it. Found by screenshot on 2026-07-30\n      and fixed on the live page with exactly this rule. ---------------------- *\/\n.bp-adv-avatar--photo{border-style:solid;padding:0;overflow:hidden;background:#fff}\n.bp-adv-avatar--photo img{width:100%;height:100%;object-fit:cover;object-position:center;border-radius:50%;display:block}\n.bp-adv-author .bp-adv-avatar-img{grid-row:1 \/ span 3;flex:0 0 auto;margin:0;width:62px;height:62px}\n.bp-adv-author .bp-adv-avatar-img img{width:62px;height:62px;object-fit:cover;object-position:center;border-radius:50%;border:2px solid var(--bp-olive);display:block}\n\n\/* --- the advertorial's own chrome (synced patterns 4822 and 4823) ------------\n   Deliberately NOT scoped to `.bp-adv`: the header and footer are siblings of\n   the article, outside that container, because canvas gives the page no chrome\n   of its own. A <style> element styles the whole document wherever it sits, so\n   these rules reach the two pattern references either side of the article. --- *\/\n.bp-adv-sitehead{background:#fff;border-bottom:1px solid #e6ece9;padding:12px 24px;margin:0}\n.bp-adv-sitehead .bp-adv-sitehead-logo{margin:0 auto;max-width:1120px}\n.bp-adv-sitehead img{height:30px;width:auto;display:block}\n.bp-adv-sitefoot{background:#f4f1ec;border-top:1px solid #e6ece9;padding:28px 24px;margin-top:44px}\n.bp-adv-sitefoot p{max-width:1120px;margin:0 auto;font-size:13px;line-height:1.8;color:#4d5f5d;text-align:center}\n.bp-adv-sitefoot a{color:#005859;text-decoration:underline}\n.bp-adv-sitefoot .bp-adv-sitefoot-legal{margin-top:6px}\n.bp-biomarker sup{font-size:.72em;line-height:0;vertical-align:super;color:var(--bp-foot);margin-left:1px}\n.bp-biomarker .bp-bm-crumbs{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker .bp-bm-crumbs a,.bp-biomarker .bp-bm-toc a,.bp-biomarker .bp-bm-src a,.bp-biomarker .bp-bm-rows a,\n.bp-biomarker .bp-bm-related a{display:inline-flex;align-items:center;min-height:44px}\n.bp-biomarker .bp-bm-names{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-4)}\n.bp-biomarker .bp-bm-toc ul{margin-block:0;padding-left:var(--bp-s-5)}\n.bp-biomarker .bp-bm-toc li{margin:0 0 var(--bp-s-1)}\n.bp-biomarker .bp-bm-src li{overflow-wrap:anywhere}\n.bp-biomarker .bp-bm-rows{list-style:none;padding-left:0}\n.bp-biomarker .bp-bm-rows li{padding-block:6px;border-bottom:1px solid var(--bp-sand)}\n.bp-biomarker .bp-bm-rows li:last-child{border-bottom:0}\n.bp-biomarker .bp-bm-rows a{font-weight:700}\n.bp-biomarker .bp-bm-count{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker figure.wp-block-table{margin-block:var(--bp-s-4) var(--bp-s-2);margin-inline:auto;overflow:visible}\n.bp-biomarker figure.wp-block-table table{table-layout:fixed;width:100%;border-collapse:collapse;\n font-size:var(--bp-fs-small);line-height:1.45;background:var(--bp-white)}\n.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{border:1px solid var(--bp-sand);\n padding:8px 10px;vertical-align:top;text-align:left;hyphens:auto;-webkit-hyphens:auto;overflow-wrap:break-word}\n.bp-biomarker figure.wp-block-table thead th{background:var(--bp-teal);color:var(--bp-white);font-weight:600}\n.bp-biomarker .bp-bm-caption{font-size:var(--bp-fs-foot);color:var(--bp-foot);margin-block:0 var(--bp-s-5)}\n@media (max-width:480px){.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{\n padding:6px 6px;font-size:13.5px}}<\/style>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/shbg\/#article\",\"headline\":\"SHBG: wat je waarde zegt over je geslachtshormonen\",\"description\":\"SHBG is een eiwit dat geslachtshormonen bindt. Lees waar een te lage of te hoge waarde op kan wijzen en wat je waarde beinvloedt.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-10\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/shbg\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/shbg\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/shbg\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"MedlinePlus, U.S. National Library of Medicine. SHBG Blood Test. Geraadpleegd op 10 oktober 2026.\",\"url\":\"https:\/\/medlineplus.gov\/lab-tests\/shbg-blood-test\/\"},{\"@type\":\"CreativeWork\",\"name\":\"Labplusarts, het laboratorium waarmee BioProfile werkt: referentiewaarde bij de bepaling shbg (SHBG), 13,2 tot 89,5 nmol\/l. Lijst van 24 september 2026.\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/shbg\/#biomarker\",\"name\":\"SHBG\",\"alternateName\":[\"SHBG\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/en\/\">Home<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/\">Biomarkers<\/a> \u203a <span>SHBG<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">SHBG: what your level says about your sex hormones<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">SHBG is a protein in your blood that binds to sex hormones such as testosterone. A low level can suggest that more of your testosterone is free. A high level can suggest that your tissues are able to use less testosterone.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">On this page, you can read what SHBG is, what the guidelines say about a level that is too low or too high, what affects your level and which other levels are best looked at alongside it.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Also known as: sex hormone-binding globulin, testosterone-oestrogen binding globulin, TeBG. At the lab: SHBG.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Updated on 10 October 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">On this page<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">In short<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-shbg\">What is SHBG?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Why SHBG matters<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">What your SHBG level tells you<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">What affects your SHBG<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Which BioProfile packages measure SHBG<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Related values<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">How this page was made<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Sources<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">In short<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>SHBG is a protein that is made mainly in your liver and binds to sex hormones such as testosterone and oestrogen.<sup>[1]<\/sup><\/li>\n\n\n<li>Hormones that are attached to SHBG cannot work with your tissues; only free hormones can.<sup>[1]<\/sup><\/li>\n\n\n<li>A low level can point to more free testosterone, and a high level to less testosterone that your tissues can use.<sup>[1]<\/sup><\/li>\n\n\n<li>Your doctor usually looks at SHBG together with your total testosterone.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-shbg\">What is SHBG?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SHBG stands for sex hormone-binding globulin. It is a protein made mainly in your liver. It binds to sex hormones such as testosterone and oestrogen. In this way, it helps determine how much of those hormones are active in your body.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The sex hormones in your blood are either bound to proteins or free. Free hormones work with your tissues. They help, for example, with the growth of bones and muscles and with your fertility. Hormones that are attached to SHBG cannot do that.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Testosterone is often called a male hormone, but women have it too, in smaller amounts. In everyone, it helps regulate your sex drive and contributes to the growth of muscle and bone.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Why SHBG matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A total testosterone test measures free and bound testosterone together. That test cannot tell the two apart. So you can have symptoms of too little or too much free testosterone, even if your total testosterone is normal. SHBG helps your doctor estimate how much testosterone is free.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In adult men, the test is often done for symptoms that may fit too little testosterone, such as a low sex drive, tiredness or less muscle mass. In adult women, it is more often about symptoms that may fit too much testosterone, such as a lot of hair growth on the face and body, acne or irregular periods.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SHBG can also help identify a hormonal condition that affects the female reproductive system. The test alone is not enough for this: your doctor looks at it alongside other results. Your doctor can also use SHBG to follow how a level changes during your care.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In children, SHBG is normally high. This means sex hormones still have little effect on the body. A low level in a child can point to puberty that starts too early.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">What your SHBG level says<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">The lab's reference range<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Labplusarts, the lab BioProfile works with, uses a reference value of 13.2 to 89.5 nmol\/l for SHBG. The lab calls a level between those limits normal.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The Labplusarts range<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Value<\/th><th>What it can mean<\/th><th>Who it is for<\/th><\/tr><\/thead><tbody><tr><td>13.2 to 89.5 nmol\/l<sup>[2]<\/sup><\/td><td>Normal according to the lab<\/td><td>The lab does not name a separate group<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Source: Labplusarts, the lab BioProfile works with. The range applies to this lab's SHBG measurement.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">SHBG too low<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A level that is too low can suggest that more of your testosterone is free and can be used by your body. According to MedlinePlus, a low level can be linked to an underactive thyroid, a metabolic condition involving insulin, severe overweight, heavy use of steroids or anabolic steroids, another hormonal condition and, in women, a hormonal condition of the reproductive system. It is also normal for SHBG to fall as you get older.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">SHBG too high<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A level that is too high can suggest that your tissues are able to use less testosterone. According to MedlinePlus, a high level can be linked to a liver condition, an overactive thyroid, certain eating disorders, in women the use of medicines containing oestrogen such as the pill or hormone therapy during the menopause, and in men a lower production of sex hormones.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile is working on its own zones for each value, from risk to optimal. A doctor reviews those zones before they appear in your result.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">What affects your SHBG<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Medicines containing hormones<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Medicines containing hormones, such as the pill, oestrogen therapy or anabolic steroids, can affect your SHBG. Tell your doctor which medicines, vitamins and supplements you take. Do not stop a medicine on your own unless your doctor tells you to.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Age<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">In children, SHBG is normally high. As you get older, SHBG often falls, because your body also makes fewer sex hormones by then.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Thyroid and liver<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">An underactive thyroid can go together with a lower level, and an overactive thyroid with a higher one. A liver condition can also go together with a higher level.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Weight and metabolism<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Severe overweight and a metabolism that responds less well to insulin can go together with a lower SHBG level.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Which BioProfile packages measure SHBG<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SHBG is included in BioProfile 121 and 150.<sup>[3]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\">View the packages<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Values that go with it<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/en\/biomarkers\/progesterone\/\">Progesterone<\/a>: another hormone level your doctor can request to see whether your hormones are in balance with each other.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>DHEA-S<\/strong>: an additional hormone test your doctor can request alongside SHBG to look at the balance between your hormones.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>Prolactin<\/strong>: a hormone level your doctor can include to see whether your hormones are in balance with each other.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>FSH<\/strong>: another hormone test your doctor can request to look at the balance between your hormones.<sup>[1]<\/sup><\/li>\n\n\n<li><strong>Parathyroid hormone<\/strong>: a hormone level your doctor can look at alongside SHBG to see whether your hormones are in balance with each other.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">How this page was made<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The BioProfile editorial team wrote this page on 10 October 2026 from the sources below, which we read on 10 October 2026. Every number on this page appears in one of those sources, with that source's number next to it. An expert has yet to check this page; after that check, the expert's name and the date of the check will appear at the top. This page offers explanation, not a diagnosis. Discuss a value outside the range with your GP.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Sources<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>MedlinePlus, U.S. National Library of Medicine. SHBG Blood Test. Accessed on 10 October 2026. <a href=\"https:\/\/medlineplus.gov\/lab-tests\/shbg-blood-test\/\" target=\"_blank\" rel=\"noopener\">https:\/\/medlineplus.gov\/lab-tests\/shbg-blood-test\/<\/a><\/li>\n\n\n<li>Labplusarts, the laboratory BioProfile works with: reference value for the shbg (SHBG) test, 13.2 to 89.5 nmol\/l. List of 24 September 2026.<\/li>\n\n\n<li>BioProfile, the blood test packages and the values in each package. <a href=\"https:\/\/bioprofile.com\/en\/blood-testing\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/en\/blood-testing\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Home \u203a Biomarkers \u203a SHBG SHBG: what your level says about your sex hormones SHBG is a protein in your blood that binds to sex hormones such as testosterone. A low level can suggest that more of your testosterone is free. A high level can suggest that your tissues are able to use less testosterone.[1] [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6592,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"SHBG in your blood: what your level tells you | BioProfile","_yoast_wpseo_metadesc":"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-15105","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>SHBG in your blood: what your level tells you | BioProfile<\/title>\n<meta name=\"description\" content=\"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SHBG in your blood: what your level tells you | BioProfile\" \/>\n<meta property=\"og:description\" content=\"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/\" \/>\n<meta property=\"og:site_name\" content=\"Bioprofile.com\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-05T06:16:42+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/shbg\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/shbg\\\/\",\"name\":\"SHBG in your blood: what your level tells you | BioProfile\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#website\"},\"datePublished\":\"2026-11-05T06:00:00+00:00\",\"dateModified\":\"2026-11-05T06:16:42+00:00\",\"description\":\"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/shbg\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/shbg\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/shbg\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/home-2026\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Biomarkers\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/biomarkers\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"SHBG\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/\",\"name\":\"Bioprofile.com\",\"description\":\"Live longer, stay younger\",\"publisher\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#organization\",\"name\":\"Bioprofile.com\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"contentUrl\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"width\":173,\"height\":48,\"caption\":\"Bioprofile.com\"},\"image\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"SHBG in your blood: what your level tells you | BioProfile","description":"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/","og_locale":"en_US","og_type":"article","og_title":"SHBG in your blood: what your level tells you | BioProfile","og_description":"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.","og_url":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/","og_site_name":"Bioprofile.com","article_modified_time":"2026-11-05T06:16:42+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/","url":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/","name":"SHBG in your blood: what your level tells you | BioProfile","isPartOf":{"@id":"https:\/\/bioprofile.com\/en\/#website"},"datePublished":"2026-11-05T06:00:00+00:00","dateModified":"2026-11-05T06:16:42+00:00","description":"SHBG is a protein that binds sex hormones. Read what a low or high level can point to and what affects your level.","breadcrumb":{"@id":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/bioprofile.com\/en\/biomarkers\/shbg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/bioprofile.com\/en\/home-2026\/"},{"@type":"ListItem","position":2,"name":"Biomarkers","item":"https:\/\/bioprofile.com\/en\/biomarkers\/"},{"@type":"ListItem","position":3,"name":"SHBG"}]},{"@type":"WebSite","@id":"https:\/\/bioprofile.com\/en\/#website","url":"https:\/\/bioprofile.com\/en\/","name":"Bioprofile.com","description":"Live longer, stay younger","publisher":{"@id":"https:\/\/bioprofile.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/bioprofile.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/bioprofile.com\/en\/#organization","name":"Bioprofile.com","url":"https:\/\/bioprofile.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/bioprofile.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","contentUrl":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","width":173,"height":48,"caption":"Bioprofile.com"},"image":{"@id":"https:\/\/bioprofile.com\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/comments?post=15105"}],"version-history":[{"count":1,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15105\/revisions"}],"predecessor-version":[{"id":15106,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/15105\/revisions\/15106"}],"up":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/pages\/6592"}],"wp:attachment":[{"href":"https:\/\/bioprofile.com\/en\/wp-json\/wp\/v2\/media?parent=15105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}