{"id":7121,"date":"2026-08-24T11:56:27","date_gmt":"2026-08-24T11:56:27","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=7121"},"modified":"2026-09-30T12:41:36","modified_gmt":"2026-09-30T12:41:36","slug":"advertorial-you-know-exactly-what-you-should-be-doing","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/en\/advertorial-you-know-exactly-what-you-should-be-doing\/","title":{"rendered":"You Know Exactly What You Should Be Doing And You Still Can&#8217;t Stay Away From It: What Researchers Measured A Year And Six Years Later"},"content":{"rendered":"\n<div class=\"wp-block-group bp-adv is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-adv-stickycta is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"bp-adv-stickycta-row\"><a class=\"bp-adv-sitehead-cta\" id=\"bp-adv-sitehead-cta\" href=\"https:\/\/app.bioprofile.com\/mini?src=site-header&amp;lang=en\">Start your analysis<\/a><\/div>\n<script id=\"bp-adv-sitehead-js\">\n(function () {\n  var TEXT = {\"analyse\": \"Start je analyse\", \"scan\": \"Start je scan\"};\n  var KEY = \"bp_adv_cta_v\";\n  var HOST = \"app.bioprofile.com\";\n  var el = document.getElementById(\"bp-adv-sitehead-cta\");\n  if (!el) { return; }\n\n  function clean(v) {\n    if (v === \"scan\") { return \"scan\"; }\n    if (v === \"analyse\") { return \"analyse\"; }\n    return null;\n  }\n  function forced() {\n    try {\n      return clean(new URLSearchParams(window.location.search).get(\"bp_cta_force\"));\n    } catch (e) { return null; }\n  }\n  function fromCookie() {\n    var hit = null;\n    String(document.cookie).split(\";\").forEach(function (part) {\n      var kv = part.split(\"=\");\n      if (kv[0].trim() === KEY) { hit = (kv[1] || \"\").trim(); }\n    });\n    return clean(hit);\n  }\n  function held() {\n    var v = null;\n    try { v = localStorage.getItem(KEY); } catch (e) { v = null; }\n    v = clean(v);\n    if (v) { return v; }\n    return fromCookie();\n  }\n  function keep(v) {\n    try { localStorage.setItem(KEY, v); return; } catch (e) {}\n    try {\n      document.cookie = KEY + \"=\" + v + \"; path=\/; max-age=15552000; samesite=lax\";\n    } catch (e) {}\n  }\n\n  var variant = forced();\n  if (!variant) {\n    variant = held();\n    if (!variant) { variant = (Math.random() > 0.5) ? \"scan\" : \"analyse\"; }\n    keep(variant);\n  }\n  el.textContent = TEXT[variant];\n\n  function stamped(href) {\n    var u;\n    try { u = new URL(href, window.location.href); } catch (e) { return null; }\n    if (u.hostname !== HOST) { return null; }\n    u.searchParams.set(\"bp_cta\", variant);\n    return u.toString();\n  }\n  var first = stamped(el.getAttribute(\"href\"));\n  if (first) { el.setAttribute(\"href\", first); }\n\n  function siteHeaderAppLinks() {\n    var out = [];\n    var heads = document.querySelectorAll(\".elementor-location-header\");\n    Array.prototype.forEach.call(heads, function (h) {\n      Array.prototype.forEach.call(h.getElementsByTagName(\"a\"), function (a) {\n        var u;\n        try { u = new URL(a.href); } catch (e) { return; }\n        if (u.hostname === HOST) { out.push(a); }\n      });\n    });\n    return out;\n  }\n  function adopt() {\n    var found = null;\n    var links = document.getElementsByClassName(\"wp-block-button__link\");\n    Array.prototype.forEach.call(links, function (a) {\n      if (found) { return; }\n      var u;\n      try { u = new URL(a.href); } catch (e) { return; }\n      if (u.hostname === HOST) { found = a.href; }\n    });\n    if (!found) { return; }\n    var out = stamped(found);\n    if (out) { el.setAttribute(\"href\", out); }\n    siteHeaderAppLinks().forEach(function (a) { a.setAttribute(\"href\", found); });\n  }\n  if (document.readyState === \"loading\") {\n    document.addEventListener(\"DOMContentLoaded\", adopt);\n  } else {\n    adopt();\n  }\n})();\n<\/script>\n<script id=\"bp-adv-stickycta-offset\">\n(function () {\n  var FALLBACK = 78;\n  var bar = document.querySelector(\".bp-adv-stickycta\");\n  if (!bar) { return; }\n  function header() {\n    var found = null;\n    var all = document.querySelectorAll(\".elementor-location-header\");\n    Array.prototype.forEach.call(all, function (h) {\n      if (found) { return; }\n      if (!h.classList.contains(\"elementor-sticky__spacer\")) { found = h; }\n    });\n    return found;\n  }\n  function set() {\n    var h = header();\n    var n = h ? Math.round(h.getBoundingClientRect().height) : 0;\n    if (n) { bar.style.setProperty(\"--bp-adv-stickycta-top\", n + \"px\"); }\n    else { bar.style.setProperty(\"--bp-adv-stickycta-top\", FALLBACK + \"px\"); }\n  }\n  set();\n  if (document.readyState === \"loading\") {\n    document.addEventListener(\"DOMContentLoaded\", set);\n  }\n  window.addEventListener(\"load\", set);\n  window.addEventListener(\"resize\", set, {passive: true});\n})();\n<\/script>\n\n<\/div>\n\n\n\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style id=\"bp-advertorial-design\">\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. Core wraps the link in .wp-block-button,\n     which is shrink-to-fit, so widening only the link leaves it content-sized. *\/\n  .bp-adv .wp-block-button { width: 100%; }\n  .bp-adv .wp-block-button__link { padding: 15px 24px; width: 100%; }\n  .bp-adv .bp-adv-numcard .wp-block-columns { gap: var(--bp-s-4); }\n}\n@media (prefers-reduced-motion: reduce) { .bp-adv * { transition-duration: 0ms; } }\n\n\/* --- the author portrait -----------------------------------------------------\n   Two shapes, because there are two ways a portrait reaches the box.\n   1. `bp-adv-avatar--photo` turns the dashed FOTO circle into a photo frame when\n      an editor drops an inline image into the placeholder paragraph.\n   2. `bp-adv-avatar-img` is the shipped path: a REAL core\/image block, so the\n      picture is click-editable and \"Vervangen\" works. The grid-row span is the\n      load-bearing line. The paragraph avatar carries `grid-row: 1 \/ span 3` in\n      the 62px + 1fr card grid; a figure that does not carry it drops the name\n      under the photo instead of beside it. Found by screenshot on 2026-07-30\n      and fixed on the live page with exactly this rule. ---------------------- *\/\n.bp-adv-avatar--photo{border-style:solid;padding:0;overflow:hidden;background:#fff}\n.bp-adv-avatar--photo img{width:100%;height:100%;object-fit:cover;object-position:center;border-radius:50%;display:block}\n.bp-adv-author .bp-adv-avatar-img{grid-row:1 \/ span 3;flex:0 0 auto;margin:0;width:62px;height:62px}\n.bp-adv-author .bp-adv-avatar-img img{width:62px;height:62px;object-fit:cover;object-position:center;border-radius:50%;border:2px solid var(--bp-olive);display:block}\n\n\/* --- the advertorial's own chrome (synced patterns 4822 and 4823) ------------\n   Deliberately NOT scoped to `.bp-adv`: the header and footer are siblings of\n   the article, outside that container, because canvas gives the page no chrome\n   of its own. A <style> element styles the whole document wherever it sits, so\n   these rules reach the two pattern references either side of the article. --- *\/\n.bp-adv-sitehead{background:#fff;border-bottom:1px solid #e6ece9;padding:12px 24px;margin:0}\n.bp-adv-sitehead .bp-adv-sitehead-logo{margin:0 auto;max-width:1120px}\n.bp-adv-sitehead img{height:30px;width:auto;display:block}\n.bp-adv-sitefoot{background:#f4f1ec;border-top:1px solid #e6ece9;padding:28px 24px;margin-top:44px}\n.bp-adv-sitefoot p{max-width:1120px;margin:0 auto;font-size:13px;line-height:1.8;color:#4d5f5d;text-align:center}\n.bp-adv-sitefoot a{color:#005859;text-decoration:underline}\n.bp-adv-sitefoot .bp-adv-sitefoot-legal{margin-top:6px}\n\n\/* T229 *\/\n\n\/* T170: the sticky header CTA. Jesse 2026-08-24 18:35. *\/\n\/* WHY THIS RULE EXISTS AND WHY IT IS FIRST. The theme ships\n   `body, html { overflow-x: hidden }` as an inline head style. overflow-x:hidden\n   forces the OTHER axis from visible to auto, so html and body both become\n   scroll containers, and a sticky element sticks to its nearest scrollport: the\n   bar was pinned to a box as tall as the whole document, which never scrolls.\n   Measured on this preview 2026-08-24: position:sticky applied, computed top 0,\n   and the bar still left the screen at y=-600 after a 600px scroll. `clip`\n   clips exactly the same overflow WITHOUT creating a scroll container, so the\n   viewport is the scrollport again and the bar sticks. Equal specificity to the\n   theme rule and later in document order, which is what wins it; a browser too\n   old for `clip` keeps `hidden` and a bar that scrolls away, which is the old\n   page and never a broken one. *\/\nhtml,body{overflow-x:clip}\n.bp-adv-sitehead.wp-block-group{position:sticky;top:0;z-index:120;background:#fff;\n  border-bottom:1px solid #e6ece9;padding:12px 24px;margin:0}\n.bp-adv-sitehead.wp-block-group>*{margin-block:0}\n.bp-adv-sitehead.is-stuck{box-shadow:0 2px 10px rgba(0,88,89,0.08)}\n.bp-adv-sitehead .bp-adv-sitehead-row{max-width:1120px;margin:0 auto;display:flex;\n  align-items:center;justify-content:space-between;gap:12px}\n.bp-adv-sitehead .bp-adv-sitehead-row>*{margin-block:0}\n.bp-adv-sitehead .bp-adv-sitehead-row .bp-adv-sitehead-logo{margin:0;max-width:none;\n  flex:0 0 auto;line-height:0}\na.bp-adv-sitehead-cta{display:inline-flex;align-items:center;justify-content:center;\n  flex:0 0 auto;min-height:40px;padding:0 22px;border-radius:999px;\n  background:#005859;color:#fff;font-family:'Poppins','Segoe UI',Arial,sans-serif;\n  font-size:15px;font-weight:600;line-height:1.2;white-space:nowrap;\n  text-decoration:none;transition:background 250ms ease}\na.bp-adv-sitehead-cta:hover,a.bp-adv-sitehead-cta:focus{background:#7CA64C;color:#fff}\na.bp-adv-sitehead-cta:focus-visible{outline:2px solid #005859;outline-offset:2px}\n\/* T188: the text link to the scans index, beside the pill. margin-left:auto takes\n   the row's free space, so link and pill sit together at the right edge and the\n   logo stays where it is. Same 40px tap height as the pill. *\/\na.bp-adv-sitehead-nav{display:inline-flex;align-items:center;margin-left:auto;\n  flex:0 0 auto;min-height:40px;padding:8px 4px;\n  font-family:'Poppins','Segoe UI',Arial,sans-serif;font-size:15px;font-weight:600;\n  line-height:1.2;color:#005859;white-space:nowrap;text-decoration:none}\na.bp-adv-sitehead-nav:hover,a.bp-adv-sitehead-nav:focus{color:#7CA64C;text-decoration:underline}\na.bp-adv-sitehead-nav:focus-visible{outline:2px solid #005859;outline-offset:2px}\n@media (max-width:767px){\n  .bp-adv-sitehead.wp-block-group{padding:12px 20px}\n  .bp-adv-sitehead .bp-adv-sitehead-row{gap:10px}\n  a.bp-adv-sitehead-nav{font-size:14px}\n  a.bp-adv-sitehead-cta{font-size:14px;padding:0 16px}\n}\n@media (prefers-reduced-motion:reduce){a.bp-adv-sitehead-cta{transition-duration:0ms}}\n\nhtml,body{overflow-x:clip}\n.bp-adv .bp-adv-stickycta{position:sticky;top:var(--bp-adv-stickycta-top,78px);\n  z-index:110;background:#fff;border-bottom:1px solid #e6ece9;padding:10px 20px;margin:0}\n.bp-adv .bp-adv-stickycta>*{margin-block:0}\n.bp-adv .bp-adv-stickycta-row{max-width:1120px;margin:0 auto;display:flex;\n  align-items:center;justify-content:flex-end;gap:12px}\n@media (min-width:768px){\n  .bp-adv .bp-adv-stickycta{display:none}\n  .bp-adv .bp-adv-stickycta+*{margin-block-start:0}\n}\n<\/style>\n<script id=\"bp-adv-attribution\">\n(function () {\n  var HOST = \"app.bioprofile.com\";\n  var KEYS = [\"utm_content\", \"bp_pl\"];\n  function forward() {\n    var q = new URLSearchParams(window.location.search);\n    var carry = [];\n    KEYS.forEach(function (k) {\n      var v = q.get(k);\n      if (v) { carry.push([k, v]); }\n    });\n    if (!carry.length) { return; }\n    var links = document.getElementsByTagName(\"a\");\n    Array.prototype.forEach.call(links, function (a) {\n      var u;\n      try { u = new URL(a.href); } catch (e) { return; }\n      if (u.hostname !== HOST) { return; }\n      carry.forEach(function (kv) { u.searchParams.set(kv[0], kv[1]); });\n      a.setAttribute(\"href\", u.toString());\n    });\n  }\n  if (document.readyState === \"loading\") {\n    document.addEventListener(\"DOMContentLoaded\", forward);\n  } else {\n    forward();\n  }\n})();\n<\/script>\n<script id=\"bp-adv-first-touch\" src=\"https:\/\/app.bioprofile.com\/app\/js\/first-touch.js\"><\/script>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero bp-adv-sec--paper is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-adv-preheadline wp-block-paragraph\">Published research into what the body does after a diet has ended \u00b7 Read this before you start again on Monday<\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">\u201cThey had known exactly what they should really be eating for 10 years, but at 10 in the evening they were still standing in front of the fridge. In 2011, researchers measured what had happened to the appetite hormones a full year after a ten-week diet.<\/h1>\n\n\n\n<p class=\"bp-adv-subheadline wp-block-paragraph\">No new plan. No stricter rules. A free five-minute check that shows which signals in your own answers speak loudest.<\/p>\n\n\n\n<div class=\"wp-block-group bp-adv-authors is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-adv-author is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-full is-resized bp-adv-avatar-img\"><img decoding=\"async\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg\" alt=\"Jesse van der Velde\" class=\"wp-image-4815\" width=\"62\" height=\"62\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg 320w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-300x300.jpg 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-150x150.jpg 150w\" sizes=\"(max-width: 62px) 100vw, 62px\" \/><\/figure>\n\n\n\n<p class=\"bp-adv-author-role wp-block-paragraph\">Written by<\/p>\n\n\n\n<p class=\"bp-adv-author-name wp-block-paragraph\">Jesse van der Velde<\/p>\n\n\n\n<p class=\"bp-adv-author-cred wp-block-paragraph\">Founder of BioProfile \u00b7 15 books, 2 of them number 1 bestsellers \u00b7 has guided more than 500,000 people since 2006<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-optional bp-off is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-adv-author is-placeholder is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-adv-avatar wp-block-paragraph\">PHOTO<\/p>\n\n\n\n<p class=\"bp-adv-author-role wp-block-paragraph\">Scientifically verified by<\/p>\n\n\n\n<p class=\"bp-adv-author-name wp-block-paragraph\">[NAME TO FOLLOW]<\/p>\n\n\n\n<p class=\"bp-adv-author-cred wp-block-paragraph\">Dutch doctor (MD) or PhD \u00b7 independent check of every advertorial<\/p>\n\n<\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">8 min read<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">\"I know exactly what I should be doing. I just can't stay away from it.\"<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">Say that sentence out loud.<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">You know how this goes. Standing at the fridge at ten in the evening. Wanting something sweet at night while you are already full. A second helping you never decided to take. Hungry again two hours after a full meal. Thinking about food while you are working. Standing eating in the kitchen without tasting it. Starting again on Monday, again. Emptying a bag you only wanted to open.<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">I am Jesse van der Velde. Not a guru and not a doctor. I study and share what published research says about how a body ages. I have been testing that on myself and with the people I guide for more than fourteen years.<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">What I hear a lot of people say is \"I apparently just don't want it enough\".<\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\"><strong>Because there is published work on what a body does after you have eaten less for a while, and it runs on for years after the diet has ended.<\/strong><\/p>\n\n\n\n<div class=\"wp-block-group bp-optional is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1520\" height=\"1009\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-wandelt-weiland.webp\" alt=\"A woman of around 50 with auburn hair and a light linen jacket walks through tall grass in a meadow with a row of pollarded willows behind it.\" class=\"wp-image-6058\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-wandelt-weiland.webp 1520w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-wandelt-weiland-300x199.webp 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-wandelt-weiland-1024x680.webp 1024w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-wandelt-weiland-768x510.webp 768w\" sizes=\"(max-width: 1520px) 100vw, 1520px\" \/><\/figure>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-optional bp-slot bp-slot--video bp-off is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"wp-block-paragraph\">VIDEO SLOT \u00b7 place a video or embed here<\/p>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--paper bp-adv-rail bp-adv-rail--left is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Why \"you need to be more motivated\u201d was never advice you could do anything with<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Almost every guru says it: set goals. Make sure you are motivated.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Picture your dream body. Find your reasons why you want it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The instruction is always the same: create more determination and healthier eating follows by itself.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That instruction has one problem. It says nothing about hunger, and hunger is the part that decides.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The instruction asks you to want something (your goal) even more than you are hungry.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But hunger is biochemical. It is measurable in a lab.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But that \u201cwanting\u201d is something you have to find in yourself that evening, on your own. And that is not easy. In fact, fighting that biochemistry turns out to be almost impossible.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Your body regulates hunger neurobiologically. And that can work against you.<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In 2014, Gregory Morton, Thomas Meek and Michael Schwartz published a review article in Nature Reviews Neuroscience.\u00b9<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What was studied: how what you eat and what you use up are kept in balance, and what happens when that balance is pushed aside.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>How<\/strong>: an overview of the neurobiology, gathered around one distinction. There is a homeostatic system whose task is to keep the amount of body fat stable over time. So that system wants to maintain your body fat. As a neurobiological system for staying alive.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the same time, there are what the authors call emergency circuits, which drive eating in response to urgent or stressful things.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These switch on your feeling of hunger. You \u201chave to eat\u201d, to maintain your body fat.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The findings<\/strong>: the homeostatic system can be pushed aside by those emergency circuits.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When those \u201cemergency circuits\u201d are kept quiet, when they are \u201cat rest\u201d, there is no strong feeling of hunger. No strong trigger to go and eat.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>But if they stay \u201con\u201d for too long, that can cause a drastic increase in body fat.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What the researchers explain in this study:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>the body recognises a biologically defendable level of body fat.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Read that again. Not a weight you happen to have. A weight your body <strong>defends<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Now what that defending looks like in a laboratory.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In 1995, Rudolph Leibel, Michael Rosenbaum and Jules Hirsch published a study in the New England Journal of Medicine.\u00b2<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What was studied: what happens to energy use when body weight is deliberately shifted, up as well as down.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>How<\/strong>: 18 people who were overweight and 23 who never had been. Energy expenditure over 24 hours, at rest and in movement, plus the energy the food itself costs, was measured repeatedly at their usual weight, again after eating less had brought them 10 to 20 per cent below it, and again after eating more had brought them 10 per cent above it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The findings<\/strong>: holding a weight 10 per cent or more below the starting point went together with a fall in total energy expenditure of 6 \u00b1 3 kcal per kilogram of fat free mass per day in the group with no history of being overweight, and 8 \u00b1 5 in the group who were overweight.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Holding a weight 10 per cent above that went together with a rise of 9 \u00b1 7 and 8 \u00b1 4. Both directions, in both groups. And the size of the change was not linked to how much fat someone carried, and not to sex either.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That symmetry is the point.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A body pushes back against a change in both directions<\/strong>, and here it did that in people who have never been heavy too.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">So your body safeguards your current body composition.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Biochemically, it works against your goals. That is what makes changing your body so hard for many people.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But it is not impossible.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Does this sound familiar?<\/strong> Take the free check now.<\/p>\n\n\n\n<div class=\"wp-block-group bp-adv-midcta is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/app.bioprofile.com\/mini?scan=metabolic-health&amp;utm_source=advertorial&amp;utm_medium=page&amp;utm_campaign=je-weet-precies-wat-je-moet-doen&amp;lang=en\">Start your analysis now<\/a><\/div>\n\n<\/div>\n\n\n\n<p class=\"bp-adv-foot wp-block-paragraph\">Our scientifically validated questionnaire gives you answers<\/p>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--paper is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Three published numbers, and what each number counts<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>50 people, ten weeks, and a measurement again a year later.<\/strong> In 2011 Priya Sumithran and colleagues published a clinical study in the New England Journal of Medicine. 50 patients who were overweight followed a very low energy diet for ten weeks. Leptin, ghrelin, peptide YY, gastric inhibitory polypeptide, glucagon-like peptide 1, amylin, pancreatic polypeptide, cholecystokinin and insulin were measured at the start, after ten weeks, and again after 62 weeks. And also how hungry people said they were.\u00b3<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>13.5 kilos, and an appetite that went up.<\/strong> The average change over the ten weeks was 13.5 \u00b1 0.5 kg. Leptin, peptide YY, cholecystokinin and insulin all fell (P&lt;0.001 for each) and amylin fell (P=0.002). Ghrelin rose (P&lt;0.001), as did gastric inhibitory polypeptide (P=0.004) and pancreatic polypeptide (P=0.008). Self reported appetite rose significantly (P&lt;0.001).\u00b3<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A year later, none of it had gone back.<\/strong> After 62 weeks leptin, peptide YY, cholecystokinin, insulin, ghrelin, gastric inhibitory polypeptide and pancreatic polypeptide were still significantly different from the start, and so was hunger (P&lt;0.001).\u00b3<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Here is what that means:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Twelve months after those ten weeks had ended, the measured hunger signal was still the signal they had during the diet.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Six years, and one result that points the other way.<\/strong> In 2016 Erin Fothergill and colleagues published a follow up measurement in Obesity on 14 of the 16 people from a television competition. At the end of that 30 week competition the average change was 58.3 \u00b1 24.9 kg and resting metabolism had fallen by 610 \u00b1 483 kcal per day. Six years later 41.0 \u00b1 31.3 kg had come back, and resting metabolism was 704 \u00b1 427 kcal per day below the starting point.\u2074<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Now the part that does not fit the easy story, printed at the same size. How much came back was not linked to how much slowdown someone had at the end of the competition (r = -0.1, P = 0.75). And the people who kept the most off after six years were in fact the ones with the most slowdown at that point (r = 0.59, P = 0.025).\u2074<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">So the slowdown is real, and it left the outcome open. Anyone who tells you that your metabolism decided how this went for you is going further than this research went.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--paper bp-adv-rail bp-adv-rail--right is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">How this goes in practice when you diet<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">You know your own version of this. Let me give you an example from one of my clients.<\/p>\n\n\n\n<div class=\"wp-block-group bp-optional is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1520\" height=\"1009\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-portret-vrouw-tuin.webp\" alt=\"A woman somewhere in the 50s, with long dark hair with grey streaks and a taupe blouse, stands in a green garden full of wild flowers and looks just past the camera.\" class=\"wp-image-6059\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-portret-vrouw-tuin.webp 1520w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-portret-vrouw-tuin-300x199.webp 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-portret-vrouw-tuin-1024x680.webp 1024w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-portret-vrouw-tuin-768x510.webp 768w\" sizes=\"(max-width: 1520px) 100vw, 1520px\" \/><\/figure>\n\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Tuesday evening. Work done. Children in bed. And there they were, eating in the kitchen without having meant to. In other words: they had walked to the kitchen without thinking, and started eating.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Then they stood there for twenty minutes being angry at themselves, which took longer than the eating itself.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For years I passed judgement on that, with my clients too. I coached them on it. Said: you need to be more motivated.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What I understand now: this point came at week 6 every time, exactly as it did during the study. The moment the body starts to defend itself. Your weight is trying to keep itself where it is.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A judgement about your character gets you nothing. Nothing constructive comes out of it. You cannot try harder to be less hungry.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What your body is defending, and for how long, is measurable. Yours has not been measured yet.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--paper is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">The four things people do first, and what each of them does and does not do<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. Starting over on Monday, stricter this time.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Whether you start again is of course yours to choose, and starting again is better than giving up on yourself.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But be clear about what it does and does not do. A stricter version gets you a faster ten weeks. It does nothing about month twelve, and after 62 weeks, in that study, every hormone measured was still where the diet had put it, and so was the hunger.\u00b3<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">How you do it instead, I am going to explain to you.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. Getting the bad food out of the house.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">An empty cupboard takes away the option standing in front of you. That is worth doing, and it is something different from being less hungry.<\/p>\n\n\n\n<div class=\"wp-block-group bp-optional is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1520\" height=\"1009\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-meeroever-riet.webp\" alt=\"A woman of around 50 with light brown hair and a light grey coat walks along a lake with reeds, hands in pockets.\" class=\"wp-image-6060\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-meeroever-riet.webp 1520w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-meeroever-riet-300x199.webp 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-meeroever-riet-1024x680.webp 1024w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/snaaien-vrouw-meeroever-riet-768x510.webp 768w\" sizes=\"(max-width: 1520px) 100vw, 1520px\" \/><\/figure>\n\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">What the study measured was appetite itself, and it went up and stayed up for a year.\u00b3 An empty cupboard has no effect on that number. It moves the moment to the shop.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3. Deciding that you have to want it more.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Here it is the target that is wrong, not the effort. In the laboratory study, energy expenditure changed in both directions, and that change was not linked to how much fat someone carried or to sex.\u00b2 A response that also occurs in people who have never been heavy is not a character trait.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>4. Blaming your metabolism for everything.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This is the same mistake in reverse, and there is just as little you can do with it. The measurement after six years found that how much came back was not linked to the slowdown at the end of the competition, and that the people who kept the most off were in fact the ones with the biggest slowdown.\u2074 The slowdown is real. It is not the thing that decides.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Four moves, one shared problem: none of them starts with what is actually going on with you.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The advice you got from other people failed. You did nothing wrong. And it can go differently.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Your body defends how much fat you have stored, but it can go differently<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This is the heart of it. If a body defends a level in both directions, then \"how much willpower do I have\" is no longer the useful question.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The question becomes: <strong>what is my body defending, and what does that cost me on an ordinary day?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">How often the craving for something sweet comes, and how strong it is. How much you move on an ordinary day. How often there is vegetable or fruit on your plate. What runs in your family. Whether anyone has ever said that a value was too high.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">And the honest limit, which the scan prints itself: this is a risk picture, not a symptom score, and a blood test confirms it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That is what the research made available. Morton and colleagues gave the defended level a name, and the circuits that cut straight through it.\u00b9 Leibel and colleagues measured the defending in both directions.\u00b2 Sumithran and colleagues showed that the appetite signal was still changed a year later.\u00b3 Fothergill and colleagues followed it out to six years and printed the result that makes it more complicated.\u2074<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What was missing: a way to lay your own answers beside it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">On one condition. That analysis has to be about you: your cravings, your movement, your plate, your family, question by question alongside what published research describes. A general list of willpower tips does not tell you which signals in your answers are the hard ones.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--prose bp-adv-sec--dark is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">A free, validated questionnaire, five minutes, and the daily capsule I use myself<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile has built that first step. A scientifically validated questionnaire, five minutes, free and with no account.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You answer questions about your movement, your food, your history and your cravings. After that you see which signals in your profile speak loudest, and what the research says about them. Not a medical examination. An analysis of your own answers. You use the outcome yourself, or you put it on the table with your doctor.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--cta bp-adv-sec--offer is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading bp-adv-offerhead\">What you can do NOW, in the next 5 minutes<\/h2>\n\n\n\n<p class=\"bp-h--center wp-block-paragraph\">You do the free check. Five minutes, no account, and there is nothing to buy.<\/p>\n\n\n\n<p class=\"bp-h--center wp-block-paragraph\">Even if you do nothing with it, you have traded \"I apparently just don't want it enough\" for an analysis of your own answers. That trade is worth five minutes.<\/p>\n\n\n\n<p class=\"bp-h--center wp-block-paragraph\">And the next time you are standing at the fridge at ten in the evening, you will know what is being defended, and by whom.<\/p>\n\n\n\n<p class=\"bp-h--center wp-block-paragraph\">Do it now, while this page is still open. Monday is coming either way.<\/p>\n\n\n\n<div class=\"wp-block-group bp-adv-ctablock is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/app.bioprofile.com\/mini?scan=metabolic-health&amp;utm_source=advertorial&amp;utm_medium=page&amp;utm_campaign=je-weet-precies-wat-je-moet-doen&amp;lang=en\">Start your scan (questionnaire)<\/a><\/div>\n\n<\/div>\n\n\n\n<p class=\"bp-adv-ctasub wp-block-paragraph\">Our scientifically validated questionnaire gives you answers<\/p>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure bp-adv-sec--paper is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-adv-disclosure wp-block-paragraph\">The scan is not a medical examination. It is an analysis of your own answers. If complaints persist, consult your doctor.<\/p>\n\n\n\n<h3 class=\"wp-block-heading bp-adv-sources\">Sources<\/h3>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist\">\n\n<li>Morton GJ, et al. (2014). Neurobiology of food intake in health and disease. <em>Nat Rev Neurosci<\/em> 15(6):367-78. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24840801\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24840801\/<\/a><\/li>\n\n\n<li>Leibel RL, et al. (1995). Changes in energy expenditure resulting from altered body weight. <em>N Engl J Med<\/em> 332(10):621-8. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7632212\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/7632212\/<\/a><\/li>\n\n\n<li>Sumithran P, et al. (2011). Long-term persistence of hormonal adaptations to weight loss. <em>N Engl J Med<\/em> 365(17):1597-604. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22029981\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/22029981\/<\/a><\/li>\n\n\n<li>Fothergill E, et al. (2016). Persistent metabolic adaptation 6 years after \"The Biggest Loser\" competition. <em>Obesity (Silver Spring)<\/em> 24(8):1612-9. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27136388\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27136388\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Start your analysis Published research into what the body does after a diet has ended \u00b7 Read this before you start again on Monday \u201cThey had known exactly what they should really be eating for 10 years, but at 10 in the evening they were still standing in front of the fridge. In 2011, researchers [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"You Know Exactly What You Should Be Doing And You Still Can't Stay Away From It: What Researchers Measured A Year And Six Years Later","_yoast_wpseo_metadesc":"No new plan. No stricter rules. A free five-minute check that shows which signals in your own answers speak loudest.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-7121","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>You Know Exactly What You Should Be Doing And You Still Can&#039;t Stay Away From It: What Researchers Measured A Year And Six Years Later<\/title>\n<meta name=\"description\" content=\"No new plan. No stricter rules. 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