{"id":6824,"date":"2026-09-24T15:15:00","date_gmt":"2026-09-24T15:15:00","guid":{"rendered":"https:\/\/bioprofile.com\/?p=6824"},"modified":"2026-09-30T22:07:07","modified_gmt":"2026-09-30T22:07:07","slug":"biological-age-versus-calendar-age","status":"publish","type":"post","link":"https:\/\/bioprofile.com\/en\/biological-age-versus-calendar-age\/","title":{"rendered":"Biological age versus calendar age: what biological age tests measure, what the numbers are linked to and what a lifestyle scan shows"},"content":{"rendered":"\n<article class=\"wp-block-group bp-blog is-layout-flow wp-block-group-is-layout-flow\">\n\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n<link rel=\"stylesheet\" href=\"https:\/\/fonts.googleapis.com\/css2?family=Poppins:wght@300;400;500;600;700&#038;display=swap\">\n<style id=\"bp-blog-design\">\n.bp-blog {\n  --bp-ink: #212527; --bp-teal: #005859; --bp-teal-deep: #006B62; --bp-emerald: #228A62;\n  --bp-green: #7CA74D; --bp-lime: #B7CB33; --bp-lime-soft: #B7CB3329; --bp-green-aa: #4F6B28;\n  --bp-beige: #EDEAE5; --bp-sand: #DBD4CB; --bp-pale-teal: #D9E6E6; --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 40px; --bp-fs-h2: 29px; --bp-fs-h3: 21px; --bp-fs-body: 17px;\n  --bp-fs-lead: 19px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px; --bp-s-5: 24px; --bp-s-6: 32px;\n  --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 875px; --bp-prose: 875px; --bp-side: 40px; --bp-portrait: 132px;\n  --bp-radius-card: 20px; --bp-radius-btn: 10px; --bp-radius-chip: 999px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10); --bp-shadow-soft: 0 2px 10px rgba(0,88,89,0.06);\n  font-family: var(--bp-font); font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  color: var(--bp-ink); background: var(--bp-white); -webkit-font-smoothing: antialiased;\n}\n.bp-blog, .bp-blog * { box-sizing: border-box; }\n.bp-blog p, .bp-blog li, .bp-blog h1, .bp-blog h2, .bp-blog h3, .bp-blog a, .bp-blog td,\n.bp-blog th, .bp-blog cite { overflow-wrap: break-word; min-width: 0; }\n.bp-blog h1, .bp-blog h2, .bp-blog h3 { text-wrap: balance; }\n.bp-blog p, .bp-blog li { text-wrap: pretty; }\n\/* WordPress core's flow layout puts 24px above every child after the first; inside\n   a grid or a flex row that is a misalignment (measured on the scan pages 2026-08-21) *\/\n.bp-blog .bp-blog-author > *, .bp-blog .bp-blog-related > *, .bp-blog .bp-blog-verify > * { margin-block: 0; }\n\n\/* --- sections: one column, the article measure, the section rhythm ------------ *\/\n.bp-blog-sec { position: relative; background: var(--bp-white); margin-block: 0;\n  padding-block: var(--bp-s-7);\n  padding-inline: max(var(--bp-side), calc((100% - var(--bp-measure)) \/ 2)); }\n.bp-blog-sec > *:last-child { margin-block-end: 0; }\n.bp-blog-sec > p, .bp-blog-sec > ul, .bp-blog-sec > ol, .bp-blog-sec > .wp-block-quote,\n.bp-blog-sec > .bp-blog-faq-item, .bp-blog-sec > .bp-blog-takeaways, .bp-blog-sec > .bp-blog-toc,\n.bp-blog-sec > .bp-blog-refs, .bp-blog-sec > .bp-blog-srclead { max-width: var(--bp-prose); }\n.bp-blog-sec--head { padding-block: var(--bp-s-7) 0; }\n.bp-blog-sec--body { padding-block: var(--bp-s-6) var(--bp-s-7); }\n.bp-blog-sec--beige { background: var(--bp-beige); }\n.bp-blog-sec--wash { background: linear-gradient(180deg, #B7CB331A 0%, #B7CB330D 100%), #FFFFFF; }\n.bp-blog-sec--tight { padding-block: var(--bp-s-6); }\n\/* A COLOURED SECTION IS A PANEL, so it carries the panel radius. 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Een systematische review vond 33 van die tests bij de mens, in het onderzoek \\\"verouderingsklokken\\\" (of \\\"epigenetische klokken\\\") genoemd, afgelezen uit bloed- en speekselmonsters. Verschillende tests geven voor dezelfde persoon een ander getal, dus er is niet \u00e9\u00e9n getal dat \\\"de\\\" biologische leeftijd is.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Op welke leeftijd verouder je het snelst?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Deze bronnen noemen geen leeftijd waarop dat gebeurt. Wat deze tests meten is tempo: DunedinPACE vergelijkt mensen van dezelfde kalenderleeftijd, op basis van 19 indicatoren van orgaansystemen die zijn gevolgd op de leeftijden 26, 32, 38 en 45 in \u00e9\u00e9n geboortecohort.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Hoe verlaag je je biologische leeftijd?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Het duidelijkste getal komt uit \u00e9\u00e9n gerandomiseerde pilotstudie: 43 mannen in de leeftijd van 50 tot 72 volgden 8 weken een programma voor voeding en leefstijl en eindigden 3,23 jaar lager op DNAmAge dan de controlegroep (p=0,018), een signaal en geen belofte. Wat daarnaast voor iedereen geldt: de Nederlandse beweegrichtlijn vraagt om minstens 150 minuten matig intensieve beweging per week, spier- en botversterkende activiteiten op twee dagen en niet lang achtereen zitten. Thuisarts.nl vult dat aan met adviezen over eten en drinken, slapen, ontspannen, sociaal contact en zingeving, en alcohol, tabak en drugs.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is de leefstijlscan een test voor je biologische leeftijd?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"De leefstijlscan is geen biologische-leeftijdstest. De scan leest je gewoontes, terwijl biologische-leeftijdstests worden afgelezen uit bloed- en speekselmonsters. 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That matters, because a number like this is an estimate from research and not a judgement about you: once you know how it comes about, you can read it calmly.<\/p>\n\n\n\n<div class=\"wp-block-group bp-blog-verify bp-blog-verify--top is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas.webp\" alt=\"Portrait of Justinas \u0160likas\" class=\"wp-image-5796\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas.webp 800w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas-240x300.webp 240w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas-768x960.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"bp-blog-verify-name wp-block-paragraph\">Verified by <a href=\"https:\/\/bioprofile.com\/experts\/justinas-slikas\/\">Justinas \u0160likas, PhD<\/a><\/p>\n\n\n\n<p class=\"bp-blog-verify-cred wp-block-paragraph\">PhD in chemistry from the University of Edinburgh<\/p>\n\n\n\n<p class=\"bp-blog-verify-date wp-block-paragraph\">Checked on 30 September 2026<\/p>\n\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">You know your calendar age to the day. The harder question is what your biological age is right now. Biological age tests, called &#8220;ageing clocks&#8221; (or &#8220;epigenetic clocks&#8221;) in the research, try to answer that question from a blood or saliva sample.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> <a href=\"https:\/\/bioprofile.com\/en\/scan-lifestyle-test\/\">The BioProfile lifestyle scan<\/a> asks about your daily habits and gives you an indication of where you stand today, as one of the 11 health areas the full scan assesses. This is not a diagnosis. It is self-insight, to see where you stand today, and to help you make better choices in your nutrition and lifestyle. What this scan does not do: name a cause or a condition. That is work for a doctor.<\/p>\n\n\n\n<div class=\"wp-block-group bp-blog-takeaways is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">In short<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>Your calendar age and an estimate of your biological age are different numbers: among 845 adults who were followed for almost 20 years, eight of the nine measures of biological age (all except telomere length) predicted mortality independently of calendar age.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/li>\n\n\n<li>There is no official biological age: a systematic review counted 33 biological age tests in humans, called \u201cageing clocks\u201d (or \u201cepigenetic clocks\u201d) in the research, read from blood and saliva.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup><\/li>\n\n\n<li>In the Dutch Rotterdam Study, a one standard deviation higher DNAm GrimAge was associated with a hazard ratio of 1.79 for all-cause mortality (95% CI 1.52 to 2.12).\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">3<\/a><\/sup><\/li>\n\n\n<li>A lifestyle scan gives you a starting value for your habits. It is not a biological age test and it is not a diagnosis.<\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-toclabel wp-block-paragraph\">Contents<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n\n<li><a href=\"#biologische-leeftijd-versus-kalenderleeftijd\">Biological age versus calendar age<\/a><\/li>\n\n\n<li><a href=\"#hoe-je-biologische-leeftijd-wordt-berekend\">How your biological age is calculated<\/a><\/li>\n\n\n<li><a href=\"#waarmee-een-hoger-getal-verband-houdt\">What a higher number is linked to<\/a><\/li>\n\n\n<li><a href=\"#op-welke-leeftijd-verouder-je-het-snelst\">At what age do you age fastest<\/a><\/li>\n\n\n<li><a href=\"#kan-je-biologische-leeftijd-omlaag\">Can your biological age go down<\/a><\/li>\n\n\n<li><a href=\"#wat-een-leefstijlscan-meet-en-wat-de-scan-niet-meet\">What a lifestyle scan measures and what the scan does not measure<\/a><\/li>\n\n\n<li><a href=\"#samengevat\">In summary<\/a><\/li>\n\n\n<li><a href=\"#veelgestelde-vragen\">Frequently asked questions<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"biologische-leeftijd-versus-kalenderleeftijd\">Biological age versus calendar age<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Your calendar age counts the years since your date of birth, at the same pace for everyone. An estimate of your biological age tries to describe how your body is doing. In a Swedish cohort of 845 adults aged 50 to 90, studied in nine measurement rounds from 1986 to 2014 with about 20 years of follow-up for mortality, eight of the nine measures of biological age (all except telomere length) predicted mortality independently of calendar age.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For you this means that your date of birth does not tell you everything. People of the same age can be in a different biological state, and in groups that difference goes together with how long people live.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"hoe-je-biologische-leeftijd-wordt-berekend\">How your biological age is calculated<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A systematic review gathered 33 biological age tests used in humans, called &#8220;ageing clocks&#8221; (or &#8220;epigenetic clocks&#8221;) in the research, with sample sizes of 53 to 62,419 people, in blood and saliva from cohorts of adults.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> Phenotypic tests combine routine measurements; epigenetic tests read chemical markings on the DNA. Second generation tests such as PhenoAge biological age and GrimAge showed a stronger link with death from any cause than first generation tests.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> So there is no official answer to the question what is my biological age: every answer names a test, a sample and a comparison group.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you see a biological age given somewhere, look at which test was used and which group you were compared with, because a different test can give you a different number.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"waarmee-een-hoger-getal-verband-houdt\">What a higher number is linked to<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In the Dutch Rotterdam Study (n=1,347, median follow-up 8.6 years), a one standard deviation higher DNAm GrimAge was associated with a hazard ratio of 1.79 for all-cause mortality (95% CI 1.52 to 2.12), and the metabolite score MetaboHealth showed the same ratio of 1.79 per standard deviation in the same cohort (95% CI 1.52 to 2.09).\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">3<\/a><\/sup> Among 1,942 participants in NHANES who were followed for a median of 208 months, every 1 unit increase in GrimAge acceleration was linked to a hazard ratio of 1.07 (95% CI 1.06 to 1.09).\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">4<\/a><\/sup> This is not a personal prediction: these are averages across groups and years.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In plain words: in these groups, more people with a higher number died during the follow-up years than people of the same age with a lower number.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"op-welke-leeftijd-verouder-je-het-snelst\">At what age do you age fastest<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">These sources do not name an age at which everyone ages fastest. What the sources measure is pace. DunedinPACE was developed in a birth cohort from 1972 and 1973 (N=1,037), out of 19 indicators of organ systems that were followed at the ages of 26, 32, 38 and 45.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">5<\/a><\/sup> Because that whole cohort was born in the same two years, the measure is about a difference in pace between people of the same calendar age. In a validation sample of 2,471 adults with an average age of 66, a standard deviation higher DunedinPACE was associated with a hazard ratio for death of 1.65 (95% CI 1.51 to 1.79).\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">5<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For you this means that the pace counts and not just the number: two people of the same age can grow older biologically at a faster or a slower rate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"kan-je-biologische-leeftijd-omlaag\">Can your biological age go down<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One randomised pilot study gives the clearest number there is: 43 men aged 50 to 72 followed a nutrition and lifestyle programme for 8 weeks, and that group ended 3.23 years lower on DNAmAge than the control group (p=0.018).\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">6<\/a><\/sup> One pilot, 43 participants, eight weeks, men only: that is not a promise but a signal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The everyday version is better documented. The Dutch physical activity guideline for adults asks for at least 150 minutes of moderately intense activity a week spread over several days, for muscle and bone strengthening activities at least twice a week, and for not sitting for long stretches at a time.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">7<\/a><\/sup> In 2025, 48% of Dutch adults aged 18 to 64 met the whole guideline.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">7<\/a><\/sup> Thuisarts.nl sorts the advice on healthy living for adults into seven areas: eating and drinking, exercise, sleep, relaxation, social contact and meaning, alcohol, tobacco and drugs, and sticking with it.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">8<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"wat-een-leefstijlscan-meet-en-wat-de-scan-niet-meet\">What a lifestyle scan measures and what the scan does not measure<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile&#8217;s lifestyle scan asks about your habits and gives you back a score with the reading band that score falls into. It is a questionnaire and not a biological age test: the tests above are read from blood and saliva samples in research cohorts.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> What you get is a starting value, and a second one if you repeat the scan later.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A questionnaire does not say what lies behind a low score. The scan is not a diagnosis. If a complaint is urgent, Thuisarts.nl points you straight to Emergency care: who do you call?\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">8<\/a><\/sup> For complaints that persist or worry you, put the question to a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"samengevat\">In summary<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Your calendar age counts years, and your biological age is an estimate of how your body is doing that every biological age test calculates in its own way. In groups, a higher number goes together with a higher risk of death, but for one person it is not a prediction. That the number can go down has been seen in one small pilot study: a signal and not a promise. The lifestyle scan does not measure biological age, but it does show where your habits stand today.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-cta is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Measure where you start<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A few questions about your daily habits, and your score is in your dashboard. What the lifestyle scan measures and what the scan is based on is on the scan page.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/en\/scan-lifestyle-test\/\">Start the lifestyle scan<\/a><\/div>\n\n<\/div>\n\n\n\n<p class=\"bp-blog-ctamicro wp-block-paragraph\">Free, about 3 minutes. An analysis of your answers, never a diagnosis. <a href=\"https:\/\/bioprofile.com\/en\/free-health-check-tests\/\">All health scans<\/a><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"veelgestelde-vragen\">Frequently asked questions<\/h2>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">How do you calculate your biological age?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Not with a sum at the kitchen table but with a biological age test. A systematic review found 33 of these tests in humans, called &#8220;ageing clocks&#8221; (or &#8220;epigenetic clocks&#8221;) in the research, read from blood and saliva samples.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> Different tests give a different number for the same person, so there is not one number that is &#8220;the&#8221; biological age.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">At what age do you age fastest?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">These sources do not name an age at which that happens. What these tests measure is pace: DunedinPACE compares people of the same calendar age, based on 19 indicators of organ systems that were followed at the ages of 26, 32, 38 and 45 in one birth cohort.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">5<\/a><\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">How do you lower your biological age?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The clearest figure comes from one randomised pilot study: 43 men aged 50 to 72 followed an 8 week nutrition and lifestyle programme and ended up 3.23 years lower on DNAmAge than the control group (p=0.018), a signal and not a promise.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">6<\/a><\/sup> What also applies to everyone: the Dutch physical activity guideline asks for at least 150 minutes of moderately intensive exercise a week, muscle and bone strengthening activities on two days, and not sitting for long stretches at a time.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">7<\/a><\/sup> Thuisarts.nl adds advice on eating and drinking, sleep, relaxation, social contact and a sense of purpose, and alcohol, tobacco and drugs.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">8<\/a><\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">Is the lifestyle scan a test for your biological age?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The lifestyle scan is not a biological age test. The scan reads your habits, while biological age tests are read from blood and saliva samples.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> The scan is not a diagnosis, and with symptoms you go to a doctor.<\/p>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--beige bp-blog-sec--tight is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bronnen\">Sources<\/h2>\n\n\n\n<p class=\"bp-blog-srclead wp-block-paragraph\">Every source below was checked on the day this article was published. The numbering follows the text.<\/p>\n\n\n\n<ol class=\"wp-block-list bp-blog-refs\">\n\n<li>Li X, Ploner A, Wang Y, et al. Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20 years follow-up. eLife, 2020. <a href=\"https:\/\/doi.org\/10.7554\/eLife.51507\">doi.org\/10.7554\/eLife.51507<\/a><\/li>\n\n\n<li>Warner B, Ratner E, Datta A, Lendasse A. A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans. Aging (Albany NY), 2024. <a href=\"https:\/\/doi.org\/10.18632\/aging.206098\">doi.org\/10.18632\/aging.206098<\/a><\/li>\n\n\n<li>Kuiper LM, Polinder-Bos HA, Bizzarri D, et al. Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk. The Journals of Gerontology: Series A, 2023;78(10):1753 to 1762. <a href=\"https:\/\/doi.org\/10.1093\/gerona\/glad137\">doi.org\/10.1093\/gerona\/glad137<\/a><\/li>\n\n\n<li>Zhu T, He Y, Wang Y, Zhao L. GrimAge and GrimAge2 Age Acceleration effectively predict mortality risk: a retrospective cohort study. Epigenetics, 2025. <a href=\"https:\/\/doi.org\/10.1080\/15592294.2025.2530618\">doi.org\/10.1080\/15592294.2025.2530618<\/a><\/li>\n\n\n<li>Belsky DW, Caspi A, Corcoran DL, et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. eLife, 2022. <a href=\"https:\/\/doi.org\/10.7554\/eLife.73420\">doi.org\/10.7554\/eLife.73420<\/a><\/li>\n\n\n<li>Fitzgerald KN, Hodges R, Hanes D, et al. Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial. Aging (Albany NY), 2021. <a href=\"https:\/\/doi.org\/10.18632\/aging.202913\">doi.org\/10.18632\/aging.202913<\/a><\/li>\n\n\n<li>Sport &#038; bewegen in cijfers (RIVM, CBS, Kenniscentrum Sport &#038; Bewegen). Physical activity guidelines, based on Gezondheidsraad 2017. Accessed 2026-09-21. <a href=\"https:\/\/www.sportenbewegenincijfers.nl\/kernindicatoren\/beweegrichtlijnen\">sportenbewegenincijfers.nl<\/a><\/li>\n\n\n<li>Thuisarts.nl (NHG). Healthy living: advice to help you feel good. Accessed 2026-09-21. <a href=\"https:\/\/www.thuisarts.nl\/gezond-leven\">thuisarts.nl<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--tight is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Written by<\/h2>\n\n\n\n<div class=\"wp-block-group bp-blog-author is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"320\" height=\"320\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg\" alt=\"Jesse van der Velde\" class=\"wp-image-4815\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg 320w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-300x300.jpg 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-150x150.jpg 150w\" sizes=\"(max-width: 320px) 100vw, 320px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-group bp-blog-authorid is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorrole wp-block-paragraph\">Founder of BioProfile<\/p>\n\n\n\n<p class=\"bp-blog-authorname wp-block-paragraph\">Jesse van der Velde<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-authorbody is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorbio wp-block-paragraph\">Jesse van der Velde has been guiding people to a new body and optimal health since 2006, and has written or co-written fifteen books on nutrition and health. Forever Young (2012) and Superfood Recipes (2013) both reached number 1 in the Netherlands.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-authormeta is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorbio wp-block-paragraph\"><a href=\"https:\/\/nl.linkedin.com\/in\/jessevdv\">LinkedIn<\/a><\/p>\n\n\n\n<p class=\"bp-blog-dates wp-block-paragraph\">Published on 24 September 2026 \u00b7 Last updated on 25 September 2026<\/p>\n\n<\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--foot is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-legal wp-block-paragraph\">BioProfile analyses your health status to guide you and your coach. It does not make a diagnosis, only a doctor can do that. Built on validated health questionnaires; the combined BioProfile score is not itself a validated clinical instrument yet. Your answers stay private (GDPR).<\/p>\n\n<\/div>\n\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Biological age versus calendar age: how biological age tests calculate their numbers, what the numbers are linked to and what a lifestyle scan shows.<\/p>\n","protected":false},"author":18,"featured_media":6132,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/bp-blog-biologische-leeftijd-versus-kalenderleeftijd-7e4879b9.webp","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/bp-blog-biologische-leeftijd-versus-kalenderleeftijd-7e4879b9.webp","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"categories":[71],"tags":[],"class_list":["post-6824","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthy-aging-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biological age versus calendar age | 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