{"id":12283,"date":"2026-10-22T10:00:00","date_gmt":"2026-10-22T10:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=12283"},"modified":"2026-11-06T03:33:48","modified_gmt":"2026-11-06T03:33:48","slug":"homa-ir","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/","title":{"rendered":"HOMA-IR"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. Core wraps the link in .wp-block-button,\n     which is shrink-to-fit, so widening only the link leaves it content-sized. *\/\n  .bp-adv .wp-block-button { width: 100%; }\n  .bp-adv .wp-block-button__link { padding: 15px 24px; width: 100%; }\n  .bp-adv .bp-adv-numcard .wp-block-columns { gap: var(--bp-s-4); }\n}\n@media (prefers-reduced-motion: reduce) { .bp-adv * { transition-duration: 0ms; } }\n\n\/* --- the author portrait -----------------------------------------------------\n   Two shapes, because there are two ways a portrait reaches the box.\n   1. `bp-adv-avatar--photo` turns the dashed FOTO circle into a photo frame when\n      an editor drops an inline image into the placeholder paragraph.\n   2. `bp-adv-avatar-img` is the shipped path: a REAL core\/image block, so the\n      picture is click-editable and \"Vervangen\" works. The grid-row span is the\n      load-bearing line. The paragraph avatar carries `grid-row: 1 \/ span 3` in\n      the 62px + 1fr card grid; a figure that does not carry it drops the name\n      under the photo instead of beside it. Found by screenshot on 2026-07-30\n      and fixed on the live page with exactly this rule. ---------------------- *\/\n.bp-adv-avatar--photo{border-style:solid;padding:0;overflow:hidden;background:#fff}\n.bp-adv-avatar--photo img{width:100%;height:100%;object-fit:cover;object-position:center;border-radius:50%;display:block}\n.bp-adv-author .bp-adv-avatar-img{grid-row:1 \/ span 3;flex:0 0 auto;margin:0;width:62px;height:62px}\n.bp-adv-author .bp-adv-avatar-img img{width:62px;height:62px;object-fit:cover;object-position:center;border-radius:50%;border:2px solid var(--bp-olive);display:block}\n\n\/* --- the advertorial's own chrome (synced patterns 4822 and 4823) ------------\n   Deliberately NOT scoped to `.bp-adv`: the header and footer are siblings of\n   the article, outside that container, because canvas gives the page no chrome\n   of its own. A <style> element styles the whole document wherever it sits, so\n   these rules reach the two pattern references either side of the article. --- *\/\n.bp-adv-sitehead{background:#fff;border-bottom:1px solid #e6ece9;padding:12px 24px;margin:0}\n.bp-adv-sitehead .bp-adv-sitehead-logo{margin:0 auto;max-width:1120px}\n.bp-adv-sitehead img{height:30px;width:auto;display:block}\n.bp-adv-sitefoot{background:#f4f1ec;border-top:1px solid #e6ece9;padding:28px 24px;margin-top:44px}\n.bp-adv-sitefoot p{max-width:1120px;margin:0 auto;font-size:13px;line-height:1.8;color:#4d5f5d;text-align:center}\n.bp-adv-sitefoot a{color:#005859;text-decoration:underline}\n.bp-adv-sitefoot .bp-adv-sitefoot-legal{margin-top:6px}\n.bp-biomarker sup{font-size:.72em;line-height:0;vertical-align:super;color:var(--bp-foot);margin-left:1px}\n.bp-biomarker .bp-bm-crumbs{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker .bp-bm-crumbs a,.bp-biomarker .bp-bm-toc a,.bp-biomarker .bp-bm-src a,.bp-biomarker .bp-bm-rows a,\n.bp-biomarker .bp-bm-related a{display:inline-flex;align-items:center;min-height:44px}\n.bp-biomarker .bp-bm-names{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-4)}\n.bp-biomarker .bp-bm-toc ul{margin-block:0;padding-left:var(--bp-s-5)}\n.bp-biomarker .bp-bm-toc li{margin:0 0 var(--bp-s-1)}\n.bp-biomarker .bp-bm-src li{overflow-wrap:anywhere}\n.bp-biomarker .bp-bm-rows{list-style:none;padding-left:0}\n.bp-biomarker .bp-bm-rows li{padding-block:6px;border-bottom:1px solid var(--bp-sand)}\n.bp-biomarker .bp-bm-rows li:last-child{border-bottom:0}\n.bp-biomarker .bp-bm-rows a{font-weight:700}\n.bp-biomarker .bp-bm-count{font-size:var(--bp-fs-small);color:var(--bp-foot);margin-block:0 var(--bp-s-3)}\n.bp-biomarker figure.wp-block-table{margin-block:var(--bp-s-4) var(--bp-s-2);margin-inline:auto;overflow:visible}\n.bp-biomarker figure.wp-block-table table{table-layout:fixed;width:100%;border-collapse:collapse;\n font-size:var(--bp-fs-small);line-height:1.45;background:var(--bp-white)}\n.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{border:1px solid var(--bp-sand);\n padding:8px 10px;vertical-align:top;text-align:left;hyphens:auto;-webkit-hyphens:auto;overflow-wrap:break-word}\n.bp-biomarker figure.wp-block-table thead th{background:var(--bp-teal);color:var(--bp-white);font-weight:600}\n.bp-biomarker .bp-bm-caption{font-size:var(--bp-fs-foot);color:var(--bp-foot);margin-block:0 var(--bp-s-5)}\n@media (max-width:480px){.bp-biomarker figure.wp-block-table th,.bp-biomarker figure.wp-block-table td{\n padding:6px 6px;font-size:13.5px}}<\/style>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-ir\/#article\",\"headline\":\"HOMA-IR: wat je waarde zegt over insulineresistentie\",\"description\":\"Wat is HOMA-IR, hoe schat het insulineresistentie uit nuchtere glucose en insuline, en waar kan een hoge waarde op wijzen? Lees het hier.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-10\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-ir\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-ir\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-ir\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"Gayoso-Diz P, Otero-Gonz\u00e1lez A, Rodriguez-Alvarez MX, et al. Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocr Disord. 2013;13:47.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24131857\/\"},{\"@type\":\"CreativeWork\",\"name\":\"Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/homa-ir\/#biomarker\",\"name\":\"HOMA-IR\",\"alternateName\":[\"HOMA-IR\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/\">Inicio<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/\">Biomarcadores<\/a> \u203a <span>HOMA-IR<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">HOMA-IR: qu\u00e9 dice tu valor sobre la resistencia a la insulina<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">En una muestra aleatoria de 2459 adultos espa\u00f1oles, el l\u00edmite del HOMA-IR se situ\u00f3 en 2,05. Fue as\u00ed cuando los investigadores se fijaron en las caracter\u00edsticas que, juntas, aumentan el riesgo metab\u00f3lico y cardiovascular.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">En esta p\u00e1gina descubrir\u00e1s qu\u00e9 es el HOMA-IR, qu\u00e9 dicen las gu\u00edas sobre un valor demasiado bajo o demasiado alto, qu\u00e9 influye en tu valor y qu\u00e9 otros valores conviene mirar junto a \u00e9l.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Tambi\u00e9n llamado: \u00edndice HOMA, homeostasis model assessment of insulin resistance. En el laboratorio: no aplica.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Actualizado el 10 de octubre de 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">En esta p\u00e1gina<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">En resumen<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-homa-ir\">\u00bfQu\u00e9 es el HOMA-IR?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa el HOMA-IR<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu valor de HOMA-IR<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu HOMA-IR<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden el HOMA-IR<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Valores relacionados<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Fuentes<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">En resumen<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>El HOMA-IR es una estimaci\u00f3n de la resistencia a la insulina: un valor calculado a partir de tu glucosa y tu insulina en ayunas.<sup>[2]<\/sup><\/li>\n\n\n<li>La estimaci\u00f3n no es muy precisa: el coeficiente de variaci\u00f3n para la resistencia a la insulina es del 31%.<sup>[2]<\/sup><\/li>\n\n\n<li>Un HOMA-IR m\u00e1s alto puede indicar un mayor riesgo metab\u00f3lico y cardiovascular.<sup>[1]<\/sup><\/li>\n\n\n<li>No hay un l\u00edmite fijo: en un estudio espa\u00f1ol se situ\u00f3 entre 1,85 y 3,46, seg\u00fan el m\u00e9todo y el grupo.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-homa-ir\">\u00bfQu\u00e9 es el HOMA-IR?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Tu glucosa y tu insulina en ayunas se mantienen en equilibrio mediante un mecanismo de retroalimentaci\u00f3n. El HOMA compara tus valores en ayunas con un modelo inform\u00e1tico de esa retroalimentaci\u00f3n.<sup>[2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As\u00ed, el modelo estima en qu\u00e9 medida intervienen la resistencia a la insulina y un d\u00e9ficit en el funcionamiento de las c\u00e9lulas beta cuando la glucosa en ayunas est\u00e1 elevada. El HOMA-IR es la parte que se refiere a la resistencia a la insulina.<sup>[2]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La estimaci\u00f3n coincidi\u00f3 bien con un m\u00e9todo de medici\u00f3n m\u00e1s completo, el clamp eugluc\u00e9mico (Rs = 0,88).<sup>[2]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa el HOMA-IR<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La resistencia a la insulina est\u00e1 relacionada con cambios en el metabolismo y en la circulaci\u00f3n sangu\u00ednea. Tambi\u00e9n est\u00e1 relacionada con un mayor riesgo cardiometab\u00f3lico.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Los investigadores consideran m\u00e1s \u00fatil elegir un l\u00edmite basado en ese riesgo que en un percentil de la poblaci\u00f3n. As\u00ed, el HOMA-IR ayuda mejor a reconocer a las personas en las que varios factores de riesgo juntos aumentan el riesgo metab\u00f3lico y cardiovascular.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Al mismo tiempo, la estimaci\u00f3n no es precisa. Seg\u00fan los investigadores, eso limita su uso.<sup>[2]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu valor de HOMA-IR<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">L\u00edmites del estudio EPIRCE<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>L\u00edmite (HOMA-IR)<\/th><th>Qu\u00e9 puede indicar<\/th><th>Para qui\u00e9n<\/th><\/tr><\/thead><tbody><tr><td>3,46<sup>[1]<\/sup><\/td><td>L\u00edmite seg\u00fan el percentil 90 de la poblaci\u00f3n<\/td><td>Adultos de una muestra espa\u00f1ola<\/td><\/tr><tr><td>2,05<sup>[1]<\/sup><\/td><td>L\u00edmite que tiene en cuenta las caracter\u00edsticas que, juntas, aumentan el riesgo cardiometab\u00f3lico<\/td><td>Adultos de una muestra espa\u00f1ola<\/td><\/tr><tr><td>1,85<sup>[1]<\/sup><\/td><td>L\u00edmite para un mayor riesgo cardiometab\u00f3lico<\/td><td>Hombres sin un trastorno conocido de la regulaci\u00f3n del az\u00facar en sangre<\/td><\/tr><tr><td>Depende de la edad<sup>[1]<\/sup><\/td><td>El l\u00edmite debe ajustarse a la edad<\/td><td>Mujeres sin un trastorno conocido de la regulaci\u00f3n del az\u00facar en sangre<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Fuente: Gayoso-Diz y otros, estudio EPIRCE (2013), una muestra aleatoria de 2459 adultos espa\u00f1oles. Estos l\u00edmites son v\u00e1lidos para ese grupo.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">HOMA-IR demasiado alto<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Un HOMA-IR por encima del l\u00edmite puede indicar resistencia a la insulina y un mayor riesgo metab\u00f3lico y cardiovascular. Qu\u00e9 l\u00edmite es el adecuado depende del grupo. En las mujeres sin un trastorno conocido de la regulaci\u00f3n del az\u00facar en sangre, el l\u00edmite debe ajustarse a la edad.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile est\u00e1 trabajando en sus propias zonas para cada valor, de riesgo a \u00f3ptimo. Un m\u00e9dico valora esas zonas antes de que aparezcan en tu resultado.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu HOMA-IR<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Tu glucosa y tu insulina en ayunas<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">El HOMA-IR queda calculado a partir de tu glucosa y tu insulina en ayunas. Si cambia una de las dos, tambi\u00e9n cambia el resultado. La estimaci\u00f3n estaba muy relacionada con la insulina en ayunas (Rs = 0,81).<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Edad y sexo<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En las mujeres sin un trastorno conocido de la regulaci\u00f3n del az\u00facar en sangre, la precisi\u00f3n del HOMA-IR estaba relacionada con la edad. En los hombres no era as\u00ed.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">La precisi\u00f3n del modelo<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">El modelo tiene una precisi\u00f3n limitada: el coeficiente de variaci\u00f3n es del 31% para la resistencia a la insulina. Seg\u00fan los investigadores, eso limita el uso de la estimaci\u00f3n.<sup>[2]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden el HOMA-IR<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">El HOMA-IR est\u00e1 incluido en BioProfile 121 y 150.<sup>[3]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\">Ver los paquetes<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Valores que la acompa\u00f1an<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/hba1c\/\">HbA1c<\/a>: otro valor sobre tu az\u00facar en sangre, adem\u00e1s de la glucosa en ayunas con la que se calcula el HOMA-IR.<sup>[2]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/trigliceridos\/\">Triglic\u00e9ridos<\/a>: un valor de grasa en tu sangre que encaja en el panorama m\u00e1s amplio del riesgo metab\u00f3lico en el que ayuda el HOMA-IR.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/acido-urico\/\">\u00c1cido \u00farico<\/a>: un valor metab\u00f3lico que conviene mirar junto al HOMA-IR para tener una visi\u00f3n m\u00e1s amplia de tu metabolismo.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/cetonas-en-orina\/\">Cetonas (orina)<\/a>: un valor de tu orina que, junto a tu glucosa y tu insulina en ayunas, aporta algo m\u00e1s sobre tu metabolismo.<sup>[2]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/glucosa-orina\/\">Glucosa (orina)<\/a>: muestra si hay glucosa en tu orina, adem\u00e1s de la glucosa en ayunas en tu sangre que usa el HOMA-IR.<sup>[2]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La redacci\u00f3n de BioProfile escribi\u00f3 esta p\u00e1gina el 10 de octubre de 2026 a partir de las fuentes que aparecen abajo, que le\u00edmos el 10 de octubre de 2026. Cada cifra de esta p\u00e1gina est\u00e1 en una de esas fuentes, con el n\u00famero de esa fuente al lado. Una persona experta todav\u00eda va a revisar esta p\u00e1gina; despu\u00e9s de esa revisi\u00f3n, su nombre y la fecha de la revisi\u00f3n aparecer\u00e1n arriba. Esta p\u00e1gina explica y no da un diagn\u00f3stico. Habla de un valor alterado con tu m\u00e9dico de cabecera.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Fuentes<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Gayoso-Diz P, Otero-Gonz\u00e1lez A, Rodriguez-Alvarez MX, et al. Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocr Disord. 2013;13:47. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24131857\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24131857\/<\/a><\/li>\n\n\n<li>Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/3899825\/<\/a><\/li>\n\n\n<li>BioProfile, los paquetes del an\u00e1lisis de sangre y los valores de cada paquete. <a href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/es\/analisis-de-sangre\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Inicio \u203a Biomarcadores \u203a HOMA-IR HOMA-IR: qu\u00e9 dice tu valor sobre la resistencia a la insulina En una muestra aleatoria de 2459 adultos espa\u00f1oles, el l\u00edmite del HOMA-IR se situ\u00f3 en 2,05. Fue as\u00ed cuando los investigadores se fijaron en las caracter\u00edsticas que, juntas, aumentan el riesgo metab\u00f3lico y cardiovascular.[1] En esta p\u00e1gina descubrir\u00e1s qu\u00e9 [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6604,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile","_yoast_wpseo_metadesc":"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-12283","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HOMA-IR: resistencia a la insulina en tu sangre | BioProfile<\/title>\n<meta name=\"description\" content=\"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile\" \/>\n<meta property=\"og:description\" content=\"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/\" \/>\n<meta property=\"og:site_name\" content=\"Bioprofile.com\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-06T03:33:48+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/homa-ir\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/homa-ir\\\/\",\"name\":\"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#website\"},\"datePublished\":\"2026-10-22T10:00:00+00:00\",\"dateModified\":\"2026-11-06T03:33:48+00:00\",\"description\":\"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/homa-ir\\\/#breadcrumb\"},\"inLanguage\":\"es-ES\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/homa-ir\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/homa-ir\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/home-2026\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Biomarcadores\",\"item\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/biomarkers\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"HOMA-IR\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#website\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/\",\"name\":\"Bioprofile.com\",\"description\":\"Live longer, stay younger\",\"publisher\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es-ES\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#organization\",\"name\":\"Bioprofile.com\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es-ES\",\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"contentUrl\":\"https:\\\/\\\/bioprofile.com\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/logo.svg\",\"width\":173,\"height\":48,\"caption\":\"Bioprofile.com\"},\"image\":{\"@id\":\"https:\\\/\\\/bioprofile.com\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile","description":"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/","og_locale":"es_ES","og_type":"article","og_title":"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile","og_description":"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.","og_url":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/","og_site_name":"Bioprofile.com","article_modified_time":"2026-11-06T03:33:48+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/","url":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/","name":"HOMA-IR: resistencia a la insulina en tu sangre | BioProfile","isPartOf":{"@id":"https:\/\/bioprofile.com\/es\/#website"},"datePublished":"2026-10-22T10:00:00+00:00","dateModified":"2026-11-06T03:33:48+00:00","description":"\u00bfQu\u00e9 es el HOMA-IR, c\u00f3mo estima la resistencia a la insulina a partir de la glucosa y la insulina en ayunas y qu\u00e9 puede indicar un valor alto? Te lo contamos aqu\u00ed.","breadcrumb":{"@id":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/#breadcrumb"},"inLanguage":"es-ES","potentialAction":[{"@type":"ReadAction","target":["https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/bioprofile.com\/es\/biomarkers\/homa-ir\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/bioprofile.com\/es\/home-2026\/"},{"@type":"ListItem","position":2,"name":"Biomarcadores","item":"https:\/\/bioprofile.com\/es\/biomarkers\/"},{"@type":"ListItem","position":3,"name":"HOMA-IR"}]},{"@type":"WebSite","@id":"https:\/\/bioprofile.com\/es\/#website","url":"https:\/\/bioprofile.com\/es\/","name":"Bioprofile.com","description":"Live longer, stay younger","publisher":{"@id":"https:\/\/bioprofile.com\/es\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/bioprofile.com\/es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es-ES"},{"@type":"Organization","@id":"https:\/\/bioprofile.com\/es\/#organization","name":"Bioprofile.com","url":"https:\/\/bioprofile.com\/es\/","logo":{"@type":"ImageObject","inLanguage":"es-ES","@id":"https:\/\/bioprofile.com\/es\/#\/schema\/logo\/image\/","url":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","contentUrl":"https:\/\/bioprofile.com\/wp-content\/uploads\/2024\/08\/logo.svg","width":173,"height":48,"caption":"Bioprofile.com"},"image":{"@id":"https:\/\/bioprofile.com\/es\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/pages\/12283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/comments?post=12283"}],"version-history":[{"count":4,"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/pages\/12283\/revisions"}],"predecessor-version":[{"id":15328,"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/pages\/12283\/revisions\/15328"}],"up":[{"embeddable":true,"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/pages\/6604"}],"wp:attachment":[{"href":"https:\/\/bioprofile.com\/es\/wp-json\/wp\/v2\/media?parent=12283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}