{"id":12819,"date":"2026-10-24T15:00:00","date_gmt":"2026-10-24T15:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=12819"},"modified":"2026-10-24T15:20:11","modified_gmt":"2026-10-24T15:20:11","slug":"nlr","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/es\/biomarkers\/nlr\/","title":{"rendered":"Ratio neutr\u00f3filos\/linfocitos"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. 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Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5-14.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11723675\/\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/nlr\/#biomarker\",\"name\":\"Neutrofielen\/lymfocyten-ratio\",\"alternateName\":[\"Neutrophil\/lymphocyte ratio\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/\">Inicio<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/\">Biomarcadores<\/a> \u203a <span>Ratio neutr\u00f3filos\/linfocitos<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">Ratio neutr\u00f3filos\/linfocitos (NLR)<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">Un estudio sigui\u00f3 a 90 pacientes en cuidados intensivos. En una operaci\u00f3n intestinal programada, la proporci\u00f3n de neutr\u00f3filos subi\u00f3 del 62,5% antes de la operaci\u00f3n al 84,4% despu\u00e9s. La proporci\u00f3n de linfocitos baj\u00f3 del 28,1% al 10,3%.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">En esta p\u00e1gina descubrir\u00e1s qu\u00e9 es la ratio neutr\u00f3filos\/linfocitos, qu\u00e9 dicen las gu\u00edas sobre un valor demasiado bajo o demasiado alto, qu\u00e9 influye en tu valor y qu\u00e9 valores conviene mirar junto a ella.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Tambi\u00e9n llamada: NLR, \u00edndice neutr\u00f3filo-linfocito, neutrophil-lymphocyte stress factor. En el laboratorio: no aplica.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Actualizado el 22 de octubre de 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">En esta p\u00e1gina<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">En resumen<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-nlr\">\u00bfQu\u00e9 es la ratio neutr\u00f3filos\/linfocitos?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa esta ratio<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu ratio neutr\u00f3filos\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu ratio neutr\u00f3filos\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden la ratio neutr\u00f3filos\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Valores relacionados<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Fuentes<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">En resumen<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>La ratio compara el n\u00famero de neutr\u00f3filos con el de linfocitos, dos tipos de gl\u00f3bulos blancos.<sup>[1]<\/sup><\/li>\n\n\n<li>Una ratio alta, con muchos neutr\u00f3filos y pocos linfocitos, puede apuntar a estr\u00e9s o a una inflamaci\u00f3n en todo el cuerpo.<sup>[1]<\/sup><\/li>\n\n\n<li>En un estudio, una mayor diferencia entre ambos iba unida a una evoluci\u00f3n m\u00e1s grave de la enfermedad en pacientes en estado grave.<sup>[1]<\/sup><\/li>\n\n\n<li>El valor puede cambiar r\u00e1pido, por ejemplo en torno a una operaci\u00f3n.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-nlr\">\u00bfQu\u00e9 es la ratio neutr\u00f3filos\/linfocitos?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La ratio neutr\u00f3filos\/linfocitos es el n\u00famero de neutr\u00f3filos dividido entre el n\u00famero de linfocitos. Ambos son gl\u00f3bulos blancos. La ratio puede calcularse a partir de los recuentos absolutos o de la proporci\u00f3n de cada tipo en el total de gl\u00f3bulos blancos.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Los neutr\u00f3filos y los linfocitos reaccionan de forma distinta ante una carga fuerte sobre el cuerpo. En el estudio, la proporci\u00f3n de neutr\u00f3filos subi\u00f3 y la de linfocitos baj\u00f3. La ratio resume esos dos movimientos en una sola cifra.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa esta ratio<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Los m\u00e9dicos de cuidados intensivos llevan mucho tiempo buscando un valor f\u00e1cil de medir que muestre cu\u00e1nto pesan el estr\u00e9s o la inflamaci\u00f3n sobre el cuerpo. La ratio sale de un recuento normal de gl\u00f3bulos blancos.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En el estudio, la gravedad de la evoluci\u00f3n de la enfermedad estaba relacionada con lo mucho que se separaban los neutr\u00f3filos y los linfocitos. Por eso, el autor propone el cociente como medida de la gravedad, con el nombre de neutrophil-lymphocyte stress factor.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Seg\u00fan el autor, en la unidad de cuidados intensivos la ratio puede determinarse cada 6 a 12 y 24 horas. Si la ratio tambi\u00e9n dice algo sobre la evoluci\u00f3n posterior es algo que todav\u00eda tendr\u00e1n que mostrar m\u00e1s estudios.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu ratio neutr\u00f3filos\/linfocitos<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Qu\u00e9 muestra el estudio de Zahorec<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Qu\u00e9 observ\u00f3 el estudio<\/th><th>Qu\u00e9 puede indicar<\/th><th>Para qui\u00e9n<\/th><\/tr><\/thead><tbody><tr><td>Neutr\u00f3filos del 62,5% al 84,4%, linfocitos del 28,1% al 10,3%<sup>[1]<\/sup><\/td><td>Puede apuntar a la reacci\u00f3n normal del sistema inmunitario ante el estr\u00e9s de una operaci\u00f3n<\/td><td>Pacientes con una operaci\u00f3n intestinal programada<\/td><\/tr><tr><td>Ya antes de la operaci\u00f3n, 83,2% de neutr\u00f3filos y 9,5% de linfocitos; despu\u00e9s, 89,9% y 7%<sup>[1]<\/sup><\/td><td>Puede apuntar a una inflamaci\u00f3n grave en el abdomen<\/td><td>Pacientes con una operaci\u00f3n abdominal urgente<\/td><\/tr><tr><td>Neutr\u00f3filos hasta el 94%, linfocitos en torno al 3,8%<sup>[1]<\/sup><\/td><td>Puede apuntar a una inflamaci\u00f3n muy grave en todo el cuerpo y a una evoluci\u00f3n grave de la enfermedad<\/td><td>Pacientes en estado grave en cuidados intensivos<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Fuente: Zahorec, 2001. Un estudio con 90 pacientes en cuidados intensivos. Las cifras son proporciones del total de gl\u00f3bulos blancos, no ratios. La fuente no da l\u00edmites para personas sanas.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Ratio neutr\u00f3filos\/linfocitos demasiado alta<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Una ratio alta significa muchos neutr\u00f3filos en relaci\u00f3n con los linfocitos. En el estudio, eso pod\u00eda apuntar a la reacci\u00f3n del sistema inmunitario ante una operaci\u00f3n, a una inflamaci\u00f3n en todo el cuerpo o a una evoluci\u00f3n m\u00e1s grave de la enfermedad. El estudio se centr\u00f3 en pacientes en estado grave en cuidados intensivos, no en personas sanas.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile est\u00e1 trabajando en sus propias zonas para cada valor, de riesgo a \u00f3ptimo. Un m\u00e9dico valora esas zonas antes de que aparezcan en tu resultado.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu ratio neutr\u00f3filos\/linfocitos<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Una operaci\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En el estudio, despu\u00e9s de una operaci\u00f3n programada subi\u00f3 la proporci\u00f3n de neutr\u00f3filos y baj\u00f3 la de linfocitos. A partir del d\u00eda siguiente a la operaci\u00f3n, los neutr\u00f3filos bajaron poco a poco y los linfocitos volvieron a subir.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Inflamaci\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En el estudio, una inflamaci\u00f3n grave en el abdomen o en todo el cuerpo iba unida a muchos neutr\u00f3filos y pocos linfocitos, a veces ya antes de una operaci\u00f3n.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">El momento de la medici\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">El reparto de los gl\u00f3bulos blancos cambia r\u00e1pido. El estudio midi\u00f3 el d\u00eda antes de la operaci\u00f3n, el mismo d\u00eda y los dos d\u00edas siguientes. As\u00ed que un valor habla sobre todo de ese momento.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden la ratio neutr\u00f3filos\/linfocitos<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La ratio neutr\u00f3filos\/linfocitos est\u00e1 en los cinco paquetes, de BioProfile 31 a BioProfile 150.<sup>[2]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\">Ver los paquetes<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Valores que la acompa\u00f1an<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/leucocitos\/\">Leucocitos<\/a>: el total de gl\u00f3bulos blancos, del que los neutr\u00f3filos y los linfocitos son una parte.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/pcr-alta-sensibilidad\/\">PCR (alta sensibilidad)<\/a>: otro valor que conviene mirar junto a la ratio cuando se trata de inflamaci\u00f3n.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/linfocitos\/\">Linfocitos<\/a>: el denominador de la ratio. En el estudio, su proporci\u00f3n baj\u00f3 mucho despu\u00e9s de una operaci\u00f3n.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/eosinofilos\/\">Granulocitos eosin\u00f3filos<\/a>: otro tipo de gl\u00f3bulo blanco del mismo recuento, que completa el cuadro junto a la ratio.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/monocitos\/\">Monocitos<\/a>: otro tipo de gl\u00f3bulo blanco del mismo recuento, que completa el cuadro junto a la ratio.<\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La redacci\u00f3n de BioProfile escribi\u00f3 esta p\u00e1gina el 22 de octubre de 2026 a partir de las fuentes que aparecen abajo, que le\u00edmos el 22 de octubre de 2026. Cada cifra de esta p\u00e1gina aparece en una de esas fuentes, con el n\u00famero de esa fuente al lado. Una persona experta todav\u00eda revisar\u00e1 esta p\u00e1gina; despu\u00e9s de esa revisi\u00f3n, su nombre y la fecha de la revisi\u00f3n aparecer\u00e1n arriba. Esta p\u00e1gina ofrece una explicaci\u00f3n y no un diagn\u00f3stico. Comenta cualquier valor an\u00f3malo con tu m\u00e9dico de cabecera.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Fuentes<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Zahorec R. Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5-14. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11723675\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/11723675\/<\/a><\/li>\n\n\n<li>BioProfile, los paquetes del an\u00e1lisis de sangre y los valores de cada paquete. <a href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/es\/analisis-de-sangre\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Inicio \u203a Biomarcadores \u203a Ratio neutr\u00f3filos\/linfocitos Ratio neutr\u00f3filos\/linfocitos (NLR) Un estudio sigui\u00f3 a 90 pacientes en cuidados intensivos. En una operaci\u00f3n intestinal programada, la proporci\u00f3n de neutr\u00f3filos subi\u00f3 del 62,5% antes de la operaci\u00f3n al 84,4% despu\u00e9s. La proporci\u00f3n de linfocitos baj\u00f3 del 28,1% al 10,3%.[1] En esta p\u00e1gina descubrir\u00e1s qu\u00e9 es la ratio neutr\u00f3filos\/linfocitos, [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6604,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"Ratio neutr\u00f3filos\/linfocitos (NLR) | BioProfile","_yoast_wpseo_metadesc":"Qu\u00e9 es la ratio neutr\u00f3filos\/linfocitos, qu\u00e9 puede indicar un valor alto, qu\u00e9 influye en tu valor y qu\u00e9 valores conviene mirar junto a ella.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-12819","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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