{"id":12920,"date":"2026-10-25T11:00:00","date_gmt":"2026-10-25T11:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=12920"},"modified":"2026-10-25T11:19:37","modified_gmt":"2026-10-25T11:19:37","slug":"indice-plaquetas-linfocitos","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/es\/biomarkers\/indice-plaquetas-linfocitos\/","title":{"rendered":"\u00cdndice plaquetas\/linfocitos"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. The quote\n       inside loses its own vertical margins, otherwise the card is one full\n       block of spacing taller than the approved page. --------------------- *\/\n.bp-adv .bp-adv-testimonial {\n  border: 1px dashed var(--bp-sand); border-left: 5px dashed var(--bp-sand);\n  background: var(--bp-white); border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-5); margin-block: var(--bp-s-5);\n}\n\/* the card IS the quote frame, so the quote inside it carries no rule and no\n   indent of its own; otherwise the copy is indented twice and wraps early *\/\n.bp-adv .bp-adv-testimonial .wp-block-quote {\n  border: 0; padding: 0; margin-block: 0; }\n.bp-adv .bp-adv-testimonial .wp-block-quote p {\n  font-size: 17px; font-weight: 500; color: var(--bp-foot); }\n\n\/* --- steps, footnotes, disclosure ------------------------------------------- *\/\n.bp-adv .bp-adv-steps {\n  max-width: 520px; margin-block: 0 var(--bp-s-5); margin-inline: auto;\n  padding-left: 0; list-style: none; counter-reset: bpstep; text-align: left;\n}\n.bp-adv .bp-adv-steps li { position: relative; padding-left: 40px;\n  margin-block-end: var(--bp-s-3); counter-increment: bpstep; }\n.bp-adv .bp-adv-steps li::before {\n  content: counter(bpstep); position: absolute; left: 0; top: 4px;\n  width: 26px; height: 26px; border-radius: 50%;\n  background: var(--bp-forest); color: var(--bp-white);\n  font-size: var(--bp-fs-small); font-weight: 700;\n  display: flex; align-items: center; justify-content: center; line-height: 1;\n}\n.bp-adv .bp-adv-foot { font-size: var(--bp-fs-foot); color: var(--bp-foot); line-height: 1.6; }\n.bp-adv-sec--dark .bp-adv-foot { color: rgba(255,255,255,0.82); }\n\/* Jesse's mandatory CTA subtext, 2026-07-30 15:59: directly under the button,\n   one notch above the microline in weight so it reads as part of the ask *\/\n.bp-adv .bp-adv-ctasub {\n  margin-block: calc(var(--bp-s-4) * -0.5) var(--bp-s-2); margin-inline: auto;\n  max-width: 460px; font-size: 15px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-teal); text-align: center;\n}\n.bp-adv .bp-adv-disclosure { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; }\n.bp-adv .bp-adv-sources { margin-block-start: var(--bp-s-5); }\n.bp-adv .bp-adv-srclist { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.6; padding-left: 20px; margin-block: 0; }\n.bp-adv .bp-adv-srclist li { margin-block-end: var(--bp-s-1); }\n.bp-adv .bp-h--center { text-align: center; }\n\n@media (max-width: 767px) {\n  .bp-adv {\n    --bp-fs-h1: 30px; --bp-fs-h2: 24px; --bp-fs-h3: 20px; --bp-fs-body: 16px;\n    --bp-fs-btn: 16px; --bp-fs-pre: 14px; --bp-side: 20px;\n    --bp-s-8: 44px; --bp-s-7: 32px;\n  }\n  .bp-adv .bp-adv-subheadline { font-size: 18px; }\n  .bp-adv .bp-adv-standfirst { font-size: 17px; }\n  .bp-adv .bp-adv-lede { font-size: 16px; }\n  .bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p { font-size: 20px; }\n  .bp-adv h2 { padding: var(--bp-s-3) var(--bp-s-4); }\n  .bp-adv .bp-adv-num-v { font-size: 36px; }\n  .bp-adv .bp-adv-authors { grid-template-columns: 1fr; gap: var(--bp-s-5); }\n  \/* the button is full width on mobile. Core wraps the link in .wp-block-button,\n     which is shrink-to-fit, so widening only the link leaves it content-sized. *\/\n  .bp-adv .wp-block-button { width: 100%; }\n  .bp-adv .wp-block-button__link { padding: 15px 24px; width: 100%; }\n  .bp-adv .bp-adv-numcard .wp-block-columns { gap: var(--bp-s-4); }\n}\n@media (prefers-reduced-motion: reduce) { .bp-adv * { transition-duration: 0ms; } }\n\n\/* --- the author portrait -----------------------------------------------------\n   Two shapes, because there are two ways a portrait reaches the box.\n   1. `bp-adv-avatar--photo` turns the dashed FOTO circle into a photo frame when\n      an editor drops an inline image into the placeholder paragraph.\n   2. `bp-adv-avatar-img` is the shipped path: a REAL core\/image block, so the\n      picture is click-editable and \"Vervangen\" works. The grid-row span is the\n      load-bearing line. 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The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases. Ann Lab Med. 2019;39(4):345-357.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30809980\/\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/plr\/#biomarker\",\"name\":\"Trombocyten\/lymfocyten-ratio\",\"alternateName\":[\"Platelet\/lymphocyte ratio\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/\">Inicio<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/\">Biomarcadores<\/a> \u203a <span>\u00cdndice plaquetas\/linfocitos<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">\u00cdndice plaquetas\/linfocitos (PLR)<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">El \u00edndice plaquetas\/linfocitos es la relaci\u00f3n entre el n\u00famero de plaquetas y el n\u00famero de linfocitos en tu sangre. Un cambio en esa relaci\u00f3n puede indicar una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">En esta p\u00e1gina descubrir\u00e1s qu\u00e9 es el \u00edndice plaquetas\/linfocitos, qu\u00e9 dicen las gu\u00edas sobre un valor demasiado bajo o demasiado alto, qu\u00e9 influye en tu valor y qu\u00e9 otros valores conviene mirar a su lado.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Tambi\u00e9n llamado: PLR, platelet-to-lymphocyte ratio, relaci\u00f3n plaquetas\/linfocitos. En el laboratorio: no aplica.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Actualizado el 23 de octubre de 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">En esta p\u00e1gina<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">En resumen<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-plr\">\u00bfQu\u00e9 es el \u00edndice plaquetas\/linfocitos?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa esta relaci\u00f3n<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu \u00edndice plaquetas\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu \u00edndice plaquetas\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden el \u00edndice plaquetas\/linfocitos<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Valores relacionados<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Fuentes<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">En resumen<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>El \u00edndice plaquetas\/linfocitos muestra c\u00f3mo se relaciona tu n\u00famero de plaquetas con tu n\u00famero de linfocitos.<sup>[1]<\/sup><\/li>\n\n\n<li>Un cambio puede indicar una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular.<sup>[1]<\/sup><\/li>\n\n\n<li>El valor dice m\u00e1s si lo lees junto con otros valores de la sangre, como el \u00edndice neutr\u00f3filos\/linfocitos.<sup>[1]<\/sup><\/li>\n\n\n<li>Todav\u00eda no hay un valor de corte fijo, porque los laboratorios a\u00fan no hacen esta medici\u00f3n de la misma manera.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-plr\">\u00bfQu\u00e9 es el cociente plaquetas\/linfocitos?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">El \u00edndice plaquetas\/linfocitos no es un tipo de c\u00e9lula de la sangre. Es una relaci\u00f3n entre dos recuentos de tu hemograma: las plaquetas y los linfocitos.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Los investigadores usan esta relaci\u00f3n como marcador de inflamaci\u00f3n. Muestra c\u00f3mo cambian ambos recuentos cuando hay una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La relaci\u00f3n se ha estudiado mucho en enfermedades graves en las que las defensas est\u00e1n debilitadas y la sangre coagula con m\u00e1s facilidad.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa este cociente<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Varios estudios observacionales grandes muestran que los cambios en esta relaci\u00f3n ayudan a valorar la gravedad de una inflamaci\u00f3n en todo el cuerpo. Se trata de enfermedades inflamatorias de las articulaciones, los m\u00fasculos y el sistema inmunitario.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En esas enfermedades inflamatorias, los cambios tambi\u00e9n ayudan a valorar si pueden aparecer otras enfermedades asociadas.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Un valor alto junto con muchas plaquetas puede ayudar al m\u00e9dico a reconocer algunas inflamaciones de los vasos sangu\u00edneos, sobre todo una inflamaci\u00f3n de las grandes arterias.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu cociente plaquetas\/linfocitos<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Lo que escriben Gasparyan y sus colegas<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Nivel<\/th><th>Puede indicar<\/th><th>Para qui\u00e9n<\/th><\/tr><\/thead><tbody><tr><td>Desviado<sup>[1]<\/sup><\/td><td>Una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular<\/td><td>Descrito como marcador general de inflamaci\u00f3n<\/td><\/tr><tr><td>Desviado<sup>[1]<\/sup><\/td><td>La gravedad de una inflamaci\u00f3n en todo el cuerpo y el riesgo de otras enfermedades asociadas<\/td><td>Personas con una enfermedad inflamatoria de las articulaciones, los m\u00fasculos o el sistema inmunitario<\/td><\/tr><tr><td>Alto, junto con muchas plaquetas<sup>[1]<\/sup><\/td><td>Algunas inflamaciones de los vasos sangu\u00edneos, sobre todo de las grandes arterias<\/td><td>Personas en las que un m\u00e9dico estudia una inflamaci\u00f3n de este tipo<\/td><\/tr><tr><td>Descendente con el tiempo<sup>[1]<\/sup><\/td><td>Una respuesta a un tratamiento que frena la inflamaci\u00f3n<\/td><td>Personas con una enfermedad inflamatoria de las articulaciones o del sistema inmunitario, en algunos estudios de larga duraci\u00f3n<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Fuente: Gasparyan y colaboradores, art\u00edculo de revisi\u00f3n sobre el \u00edndice plaquetas\/linfocitos como marcador de inflamaci\u00f3n en enfermedades inflamatorias de las articulaciones, los m\u00fasculos y el sistema inmunitario. La fuente no da valores de corte fijos.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cociente plaquetas\/linfocitos demasiado alto<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Un valor alto puede indicar una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular. Junto con muchas plaquetas, puede ayudar a reconocer algunas inflamaciones de los vasos sangu\u00edneos. La fuente recomienda leer siempre el valor junto con otros valores de la sangre.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile est\u00e1 trabajando en sus propias zonas para cada valor, de riesgo a \u00f3ptimo. Un m\u00e9dico valora esas zonas antes de que aparezcan en tu resultado.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu cociente plaquetas\/linfocitos<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Inflamaci\u00f3n y coagulaci\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Cuando hay una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular, cambian tus recuentos de plaquetas y de linfocitos. Por eso cambia tambi\u00e9n la relaci\u00f3n.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cuidados que frenan la inflamaci\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Algunos estudios de larga duraci\u00f3n en enfermedades inflamatorias de las articulaciones y del sistema inmunitario vieron que la relaci\u00f3n bajaba durante un tratamiento que frena la inflamaci\u00f3n. As\u00ed, el valor muestra c\u00f3mo evoluciona durante el tratamiento.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">La propia medici\u00f3n<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Los errores antes de que la sangre se mida en el laboratorio y las diferencias en c\u00f3mo miden los laboratorios pueden influir en el resultado. Seg\u00fan la fuente, esas son las mayores limitaciones de la investigaci\u00f3n sobre este valor.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden el cociente plaquetas\/linfocitos<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">El cociente plaquetas\/linfocitos est\u00e1 en los cinco paquetes, de BioProfile 31 a BioProfile 150.<sup>[2]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\">Ver los paquetes<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Valores que la acompa\u00f1an<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/leucocitos\/\">Leucocitos<\/a>: el total de gl\u00f3bulos blancos, para que veas los linfocitos dentro del conjunto.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/pcr-alta-sensibilidad\/\">PCR (alta sensibilidad)<\/a>: otro valor de inflamaci\u00f3n, para que pongas la relaci\u00f3n junto a una segunda medida de la inflamaci\u00f3n.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/linfocitos\/\">Linfocitos<\/a>: uno de los dos recuentos de la relaci\u00f3n, para que veas cu\u00e1l de los dos provoca el cambio.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/eosinofilos\/\">Granulocitos eosin\u00f3filos<\/a>: otro tipo de gl\u00f3bulo blanco del mismo hemograma, que completa la imagen de tus defensas.<\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/monocitos\/\">Monocitos<\/a>: seg\u00fan la fuente, los cambios en los monocitos, las plaquetas y los linfocitos, entre otros, muestran c\u00f3mo una enfermedad inflamatoria afecta a varios \u00f3rganos.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La redacci\u00f3n de BioProfile escribi\u00f3 esta p\u00e1gina el 23 de octubre de 2026 a partir de las fuentes que aparecen abajo, que le\u00edmos el 23 de octubre de 2026. Cada cifra de esta p\u00e1gina est\u00e1 en una de esas fuentes, con el n\u00famero de la fuente al lado. Una persona experta revisar\u00e1 todav\u00eda esta p\u00e1gina; despu\u00e9s de esa revisi\u00f3n, su nombre y la fecha de la revisi\u00f3n aparecer\u00e1n arriba. Esta p\u00e1gina ofrece informaci\u00f3n y no un diagn\u00f3stico. Si tienes un valor alterado, com\u00e9ntalo con tu m\u00e9dico de cabecera.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Fuentes<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Gasparyan AY, Ayvazyan L, Mukanova U, et al. The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases. Ann Lab Med. 2019;39(4):345-357. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30809980\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30809980\/<\/a><\/li>\n\n\n<li>BioProfile, los paquetes del an\u00e1lisis de sangre y los valores de cada paquete. <a href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/es\/analisis-de-sangre\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Inicio \u203a Biomarcadores \u203a \u00cdndice plaquetas\/linfocitos \u00cdndice plaquetas\/linfocitos (PLR) El \u00edndice plaquetas\/linfocitos es la relaci\u00f3n entre el n\u00famero de plaquetas y el n\u00famero de linfocitos en tu sangre. Un cambio en esa relaci\u00f3n puede indicar una inflamaci\u00f3n aguda o una tendencia de la sangre a coagular.[1] En esta p\u00e1gina descubrir\u00e1s qu\u00e9 es el \u00edndice plaquetas\/linfocitos, [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6604,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"\u00cdndice plaquetas\/linfocitos (PLR) | BioProfile","_yoast_wpseo_metadesc":"Qu\u00e9 dice el \u00edndice plaquetas\/linfocitos sobre la inflamaci\u00f3n en tu sangre, qu\u00e9 puede indicar un valor alto y qu\u00e9 otros valores conviene mirar a su lado.","_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"class_list":["post-12920","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site 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