{"id":16487,"date":"2026-11-13T06:00:00","date_gmt":"2026-11-13T06:00:00","guid":{"rendered":"https:\/\/bioprofile.com\/?page_id=16487"},"modified":"2026-11-13T06:35:16","modified_gmt":"2026-11-13T06:35:16","slug":"cistatina-c","status":"publish","type":"page","link":"https:\/\/bioprofile.com\/es\/biomarkers\/cistatina-c\/","title":{"rendered":"Cistatina C"},"content":{"rendered":"\n<div id=\"content\" tabindex=\"-1\"><\/div>\n<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Poppins:ital,wght@0,400;0,600;0,700;0,800;1,400&display=swap');\n\/* ===========================================================================\n   BioProfile advertorial, the design Jesse approved on 2026-07-30, expressed\n   as a WordPress design system.\n\n   THE @import IS LOAD BEARING and must stay the first thing in this sheet (a\n   CSS @import after any rule is dropped by the parser). elementor_canvas does\n   not enqueue the theme's fonts, so without it the whole page falls back to the\n   system font. Caught by LOOKING at the live page on 2026-07-30, right after\n   the template was switched to canvas.\n\n   Everything is scoped to `.bp-adv`, so nothing here can reach the rest of\n   bioprofile.com, and core blocks are styled BY ELEMENT so a heading, a\n   paragraph, a quote, a list, an image or a button inserted by hand inside the\n   advertorial comes out on-design with no class to remember.\n\n   Jesse's design feedback, 2026-07-29 23:38, point by point:\n   1. the light green and the dark green are the preferred colours; grey may be\n      used but the page must NOT open grey;\n   2. more colour and variation across sections, e.g. a colour block on the left\n      or the right side of a section, without overdesign;\n   3. ONE H1, plain text on white; everything else H2 or H3; an H2 may carry its\n      own background colour so the page can be read from the headings alone; an\n      H3 keeps its section background and gets a bigger font size;\n   4. reuse the results page design feel;\n   5. Written by \/ Verified by, the placeholder blocks and noindex stay.\n\n   COLOUR PROVENANCE. Not one hex is invented.\n   - #b7cb32  LIGHT GREEN, brand manual \"colours rejuvenation protocol\"\n              (R183 G203 B51). Same value as --bp-lime in\n              brands\/bioprofile\/brand\/tokens.md.\n   - #006b62  DARK GREEN, brand manual, nourish the cells (R0 G107 B98).\n   - #005859  brand manual primary teal, the value the brand is built on.\n   - #228a62  brand manual, challenge the body (R34 G138 B98).\n   - #7ca64c  brand manual, calm the mind (R124 G166 B76).\n   - #dbd4cd  brand manual \"additional color\", the warm neutral.\n   - #B7CB3329 is the brand token --bp-lime-soft (light green at 16 percent).\n   - the gradients are the brand token layer's own, copied verbatim.\n\n   SPECIFICITY NOTE. Elementor's global kit emits `.elementor-kit-6 h2` style\n   rules at (0,1,1). Element rules below are written `.bp-adv h2`, also (0,1,1),\n   and win on source order because this sheet is inline in the body while the\n   kit is a <link> in the head. Component rules that MUST NOT lose carry two\n   classes, e.g. `.bp-adv .wp-block-button__link`.\n\n   LAYOUT NOTE. Vertical rhythm uses `margin-block` and never the `margin`\n   shorthand, so the measure rule `.bp-adv-sec > * { margin-inline: auto }` can\n   centre a block without being outranked by its own element rule.\n   =========================================================================== *\/\n\n.bp-adv {\n  --bp-ink: #212527;\n  --bp-teal: #005859;\n  --bp-forest: #006B62;\n  --bp-emerald: #228A62;\n  --bp-olive: #7CA64C;\n  --bp-lime: #B7CB33;\n  --bp-lime-soft: #B7CB3329;\n  --bp-sand: #DBD4CB;\n  --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-grad-dark: linear-gradient(237deg, rgba(0,88,89,0.00) 62.94%, #005859 100%), linear-gradient(90deg, rgba(34,138,98,0.00) 40%, #228A62 100%), #006B62;\n  --bp-grad-lime: linear-gradient(110deg, rgba(183,203,51,0.00) 36.06%, rgba(183,203,51,0.25) 97.65%), #FFFFFF;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 44px; --bp-fs-h2: 31px; --bp-fs-h3: 24px; --bp-fs-pre: 15px;\n  --bp-fs-body: 17px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-1: 4px; --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px;\n  --bp-s-5: 24px; --bp-s-6: 32px; --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 760px; --bp-side: 40px;\n  --bp-radius-photo: 16px; --bp-radius-btn: 10px; --bp-radius-card: 20px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10);\n  font-family: var(--bp-font);\n  font-size: var(--bp-fs-body);\n  line-height: var(--bp-lh-body);\n  color: var(--bp-ink);\n  background: var(--bp-white);\n  -webkit-font-smoothing: antialiased;\n}\n.bp-adv, .bp-adv * { box-sizing: border-box; }\n.bp-adv p, .bp-adv li, .bp-adv h1, .bp-adv h2, .bp-adv h3, .bp-adv blockquote,\n.bp-adv a, .bp-adv cite, .bp-adv span { overflow-wrap: break-word; min-width: 0; }\n\n\/* THE TOGGLE. One word in the block's own \"Additional CSS class(es)\" field\n   hides an optional component on the front end without deleting anything. *\/\n.bp-adv .bp-off { display: none !important; }\n\n\/* the page opens on green, never on grey (his point 1) *\/\n.bp-adv .bp-adv-rule {\n  height: 6px; border: 0; margin-block: 0; max-width: none;\n  background: linear-gradient(90deg, #005859 0%, #006B62 38%, #228A62 66%, #B7CB33 100%);\n}\n\n\/* --- section surfaces ------------------------------------------------------ *\/\n.bp-adv-sec { position: relative; background: var(--bp-white);\n  padding: var(--bp-s-8) var(--bp-side); margin-block: 0; }\n\/* the measure: every direct child of a section is the 760px text column *\/\n.bp-adv-sec > * { max-width: var(--bp-measure); margin-inline: auto; }\n.bp-adv-sec > *:last-child { margin-block-end: 0; }\n.bp-adv-sec--wash  { background: linear-gradient(180deg, #B7CB331F 0%, #B7CB3312 100%), #FFFFFF; }\n.bp-adv-sec--dark  { background: var(--bp-grad-dark); color: var(--bp-white); }\n.bp-adv-sec--dark p, .bp-adv-sec--dark cite, .bp-adv-sec--dark li { color: var(--bp-white); }\n.bp-adv-sec--offer { background: var(--bp-grad-lime); text-align: center; }\n.bp-adv-sec--hero  { padding-block-start: var(--bp-s-6); }\n.bp-adv-sec--disclosure { padding-block: var(--bp-s-6);\n  border-top: 1px solid var(--bp-sand); }\n\n\/* --- the side accent bar, his own example (\"a colour block on the left or the\n       right side of a section\"), design rev 3: a slim vertical bar hugging the\n       text column rather than a wide margin panel. Below 1100px the margin is\n       gone, so it becomes a slim top edge. ---------------------------------- *\/\n.bp-adv-rail { overflow: hidden; }\n.bp-adv-rail::before {\n  content: \"\"; position: absolute; top: var(--bp-s-7); bottom: var(--bp-s-7);\n  width: 6px; border-radius: 3px;\n  background: linear-gradient(180deg, var(--bp-forest) 0%, var(--bp-lime) 100%);\n}\n.bp-adv-rail--left::before  { left: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n.bp-adv-rail--right::before { right: calc((100% - var(--bp-measure)) \/ 2 - 34px); }\n@media (max-width: 1099px) {\n  .bp-adv-rail::before { left: 0; right: 0; width: auto; bottom: auto; top: 0;\n    height: 4px; border-radius: 0; background: var(--bp-lime); }\n}\n\n\/* --- CORE BLOCKS, styled by element. This is the part that makes an inserted\n       block come out on-design with no class. --------------------------------- *\/\n.bp-adv p { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv h1 { font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); }\n\/* an H2 is its own colour band, so the page can be read from the headings\n   alone (his point 3). Dark green on light sections, light green on the dark\n   one, so a heading always wins against its own background. *\/\n.bp-adv h2 {\n  font-size: var(--bp-fs-h2); font-weight: 700; line-height: 1.28;\n  margin-block: 0 var(--bp-s-5);\n  background: var(--bp-grad-dark); color: var(--bp-white);\n  padding: var(--bp-s-4) var(--bp-s-5);\n  border-radius: var(--bp-radius-btn);\n  border-left: 6px solid var(--bp-lime);\n}\n.bp-adv-sec--dark h2 { background: var(--bp-lime); color: var(--bp-ink);\n  border-left-color: var(--bp-forest); }\n\/* H3: same background as its section, bigger font (his point 3, verbatim) *\/\n.bp-adv h3 { font-size: var(--bp-fs-h3); font-weight: 700; line-height: 1.35;\n  color: var(--bp-forest); background: transparent; margin-block: 0 var(--bp-s-3); }\n.bp-adv-sec--dark h3 { color: var(--bp-lime); }\n.bp-adv ul, .bp-adv ol { font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  margin-block: 0 var(--bp-s-5); padding-left: var(--bp-s-5); }\n.bp-adv li { margin-block-end: var(--bp-s-2); }\n.bp-adv a { color: var(--bp-teal); text-decoration: underline; }\n.bp-adv a:hover { color: var(--bp-olive); }\n.bp-adv-sec--dark a, .bp-adv-sec--dark strong { color: var(--bp-lime); }\n.bp-adv strong { font-weight: 700; }\n\/* the highlight pill. Colours ride on the inline style core writes, so only\n   the shape lives here and any <mark> in the article picks it up. *\/\n.bp-adv mark {\n  padding: 0 10px; border-radius: 10px; display: inline;\n  -webkit-box-decoration-break: clone; box-decoration-break: clone;\n}\n\/* figures match the approved page exactly: card radius plus the soft shadow,\n   and a left-aligned caption rather than core's centred one *\/\n.bp-adv .wp-block-image { margin-block: var(--bp-s-5); margin-inline: auto; }\n.bp-adv .wp-block-image img { display: block; width: 100%; height: auto;\n  border-radius: var(--bp-radius-card); box-shadow: var(--bp-shadow); }\n.bp-adv .wp-block-image figcaption { font-size: var(--bp-fs-foot); line-height: 1.55;\n  color: var(--bp-foot); text-align: left; margin-block: var(--bp-s-2) 0; }\n.bp-adv .wp-block-embed, .bp-adv .wp-block-video { margin-block: var(--bp-s-5); }\n.bp-adv .wp-block-embed iframe, .bp-adv .wp-block-video video {\n  width: 100%; border-radius: var(--bp-radius-photo); }\n.bp-adv .wp-block-separator:not(.bp-adv-rule) { border: 0; border-top: 1px solid var(--bp-sand);\n  margin-block: var(--bp-s-5); }\n\n\/* quotes: core pullquote and core quote both land on the lime rule. The\n   font-size reset undoes core's own 1.5em on the figure, which would otherwise\n   leak into anything inside the quote that has no size of its own. *\/\n\/* margin-inline is load bearing, and it must be `auto` rather than `0`.\n   `blockquote` and `figure` carry a 40px side margin in the browser's own\n   default stylesheet, which indents the quote inside its rule and makes the\n   copy wrap early on a phone. But these blocks are direct children of a\n   section, so zeroing the side margin also defeats the measure rule\n   `.bp-adv-sec > * { margin-inline: auto }` and pins them to the left edge. *\/\n.bp-adv .wp-block-pullquote, .bp-adv .wp-block-quote {\n  border: 0; border-left: 5px solid var(--bp-lime); background: transparent;\n  padding: var(--bp-s-2) 0 var(--bp-s-2) var(--bp-s-5);\n  margin-block: var(--bp-s-5); margin-inline: auto;\n  text-align: left; font-size: var(--bp-fs-body);\n}\n.bp-adv .wp-block-pullquote blockquote { border: 0; margin: 0; padding: 0; }\n.bp-adv .wp-block-pullquote p, .bp-adv .wp-block-quote p {\n  font-size: 24px; line-height: 1.45; font-weight: 600;\n  margin-block: 0 var(--bp-s-2); color: var(--bp-forest); }\n.bp-adv .wp-block-pullquote cite, .bp-adv .wp-block-quote cite {\n  display: block; margin: 0; font-size: var(--bp-fs-small); color: var(--bp-foot);\n  font-style: normal; text-transform: none; }\n\n\/* buttons: two classes so core's own .wp-block-button__link cannot win *\/\n.bp-adv .wp-block-buttons { display: flex; justify-content: center;\n  margin-block: 0 var(--bp-s-4); }\n.bp-adv .wp-block-button__link {\n  display: inline-flex; align-items: center; justify-content: center; min-height: 48px;\n  background: var(--bp-teal); color: var(--bp-white); font-size: var(--bp-fs-btn);\n  font-weight: 700; line-height: 1.2; border-radius: var(--bp-radius-btn);\n  padding: 15px 44px; text-decoration: none; transition: background 250ms ease;\n  box-shadow: var(--bp-shadow);\n}\n.bp-adv .wp-block-button__link:hover { background: var(--bp-olive); color: var(--bp-white); }\n\n\/* --- slot 1: pre-headline, headline, sub-headline (Jesse's headline skill) --- *\/\n.bp-adv .bp-adv-preheadline {\n  color: var(--bp-forest); font-size: var(--bp-fs-pre); font-weight: 600; line-height: 1.5;\n  border-left: 4px solid var(--bp-lime); padding-left: var(--bp-s-3);\n  margin-block: 0 var(--bp-s-4);\n}\n.bp-adv .bp-adv-subheadline { font-size: 21px; line-height: 1.5; font-weight: 600;\n  color: var(--bp-forest); margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-standfirst { font-size: 19px; line-height: 1.65;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-lede { font-size: 18px; line-height: 1.7;\n  margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-byline { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  line-height: 1.6; margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-socialproof { font-size: var(--bp-fs-small); color: var(--bp-foot);\n  margin-block: 0 var(--bp-s-5); }\n\/* the offer headline above the CTA. Jesse asked for a second H1 here; the brand\n   doc's accessibility rule is one h1 per page, so it is rendered at H1 size and\n   stays an h2 element. Named in the close as the one design conflict. *\/\n.bp-adv h2.bp-adv-offerhead {\n  font-size: var(--bp-fs-h1); font-weight: 700; line-height: 1.22;\n  margin-block: 0 var(--bp-s-4); text-align: center; color: var(--bp-ink);\n  background: none; padding: 0; border: 0; border-radius: 0;\n}\n\n\/* --- Written by + Verified by. The avatar is the first child and spans the\n       three text rows, so the whole box is four ordinary paragraphs and stays\n       editable without nested columns. ---------------------------------------- *\/\n.bp-adv .bp-adv-authors {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-top: 4px solid var(--bp-lime); border-radius: var(--bp-radius-card);\n  box-shadow: var(--bp-shadow); padding: var(--bp-s-5);\n  margin-block: 0 var(--bp-s-4);\n  \/* auto-fit, so switching the verified box off leaves one full-width author\n     rather than a half-empty card *\/\n  display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));\n  gap: var(--bp-s-5); align-items: start;\n}\n.bp-adv .bp-adv-author {\n  display: grid; grid-template-columns: 62px 1fr; gap: 0 var(--bp-s-3);\n  align-items: start; min-width: 0;\n}\n.bp-adv .bp-adv-avatar {\n  grid-row: 1 \/ span 3; width: 62px; height: 62px; border-radius: 50%;\n  background: #B7CB331F; border: 2px dashed var(--bp-olive);\n  display: flex; align-items: center; justify-content: center;\n  font-size: 10px; font-weight: 700; letter-spacing: 0.06em; color: var(--bp-forest);\n  margin-block: 0;\n}\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-avatar {\n  border-color: var(--bp-sand); background: #fff; color: var(--bp-foot); }\n.bp-adv .bp-adv-author-role {\n  font-size: 11px; font-weight: 700; letter-spacing: 0.08em; text-transform: uppercase;\n  color: var(--bp-forest); line-height: 1.6; margin-block: 0; }\n.bp-adv .bp-adv-author.is-placeholder .bp-adv-author-role { color: var(--bp-foot); }\n.bp-adv .bp-adv-author-name { font-size: 17px; font-weight: 700; line-height: 1.35;\n  margin-block: 0; }\n.bp-adv .bp-adv-author-cred { font-size: var(--bp-fs-foot); color: var(--bp-foot);\n  line-height: 1.55; margin-block: 0; }\n\/* the optional wrapper must not break the two-column grid of the box *\/\n.bp-adv .bp-adv-authors > .bp-optional { display: contents; }\n.bp-adv .bp-adv-authors > .bp-optional.bp-off { display: none !important; }\n\n\/* --- placeholders: image slot, video slot ---------------------------------- *\/\n.bp-adv .bp-slot {\n  display: flex; align-items: center; justify-content: center; text-align: center;\n  min-height: 180px; padding: var(--bp-s-4); margin-block: var(--bp-s-5) 0;\n  border: 2px dashed var(--bp-olive); border-radius: var(--bp-radius-photo);\n  background: #B7CB331F; color: var(--bp-forest);\n}\n.bp-adv .bp-slot p { font-size: var(--bp-fs-small); font-weight: 700; margin-block: 0; }\n.bp-adv .bp-slot--video { min-height: 260px; }\n\n\/* --- mid-article CTA band --------------------------------------------------- *\/\n.bp-adv .bp-adv-midcta {\n  background: var(--bp-grad-lime); border: 1px solid var(--bp-lime);\n  border-radius: var(--bp-radius-card); padding: var(--bp-s-5) var(--bp-s-4);\n  margin-block: var(--bp-s-6); text-align: center;\n}\n.bp-adv .bp-adv-midcta .wp-block-buttons { margin-block-end: var(--bp-s-2); }\n.bp-adv .bp-adv-midcta .bp-adv-foot { margin-block: 0; }\n\n\/* the closing CTA is one named unit in List View, so it moves and toggles as a\n   whole. It carries no box of its own: the spacing must read exactly as it does\n   on the approved page, where the three parts are plain siblings. *\/\n.bp-adv .bp-adv-ctablock { margin-block: 0 var(--bp-s-5); }\n.bp-adv .bp-adv-ctablock .wp-block-buttons { margin-block-end: var(--bp-s-4); }\n.bp-adv .bp-adv-ctablock .bp-adv-foot { margin-block: 0; }\n\n\/* --- the condition, slot 8: the results page reference-card shape ----------- *\/\n.bp-adv .bp-adv-condition {\n  background: var(--bp-white); border: 1px solid var(--bp-sand);\n  border-left: 5px solid var(--bp-lime); border-radius: var(--bp-radius-btn);\n  padding: var(--bp-s-4) var(--bp-s-5); font-weight: 600; box-shadow: var(--bp-shadow);\n}\n\n\/* --- the numbers card: the results page focus panel, same gradient, same\n       radius, same lime figures (\"use more of that design\") ------------------ *\/\n.bp-adv .bp-adv-numcard {\n  background: linear-gradient(135deg, var(--bp-teal) 0%, var(--bp-forest) 100%);\n  border-radius: var(--bp-radius-card);\n  padding: var(--bp-s-6) var(--bp-s-5) var(--bp-s-5);\n  box-shadow: var(--bp-shadow); margin-block: var(--bp-s-5) 0;\n  position: relative; overflow: hidden;\n}\n.bp-adv .bp-adv-numcard::after {\n  content: \"\"; position: absolute; right: -70px; top: -70px; width: 240px; height: 240px;\n  border-radius: 50%; background: rgba(255,255,255,0.05); pointer-events: none;\n}\n.bp-adv .bp-adv-numcard .wp-block-columns {\n  position: relative; z-index: 1; gap: var(--bp-s-5); margin-block: 0; }\n.bp-adv .bp-adv-numcard .wp-block-column { min-width: 0; }\n.bp-adv .bp-adv-num-v { font-size: 44px; font-weight: 700; line-height: 1.12;\n  color: var(--bp-lime); text-align: center; margin-block: 0 var(--bp-s-2); }\n.bp-adv .bp-adv-num-l { font-size: var(--bp-fs-small); line-height: 1.5;\n  color: rgba(255,255,255,0.92); text-align: center; margin-block: 0; }\n.bp-adv .bp-adv-numsrc { margin-block: var(--bp-s-5) 0; }\n\n\/* --- the proof slot: a dashed card until a consented quote exists. 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Helder uitgelegd, met bronnen.\",\"inLanguage\":\"nl-NL\",\"dateModified\":\"2026-10-10\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/cystatine-c\/\"},\"isPartOf\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/cystatine-c\/\"},\"publisher\":{\"@id\":\"https:\/\/bioprofile.com\/#organization\"},\"about\":{\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/cystatine-c\/#biomarker\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"Inker LA, Schmid CH, Tighiouart H, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012;367(1):20-9.\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22762315\/\"},{\"@type\":\"CreativeWork\",\"name\":\"Labplusarts, het laboratorium waarmee BioProfile werkt: referentiewaarde bij de bepaling cystatine c (CYSTAT), 0,64 tot 1,12 mg\/L. Lijst van 24 september 2026.\"},{\"@type\":\"CreativeWork\",\"name\":\"BioProfile, de pakketten van het bloedonderzoek en de waarden in elk pakket.\",\"url\":\"https:\/\/bioprofile.com\/bloedonderzoek\/\"}]},{\"@type\":\"MedicalTest\",\"@id\":\"https:\/\/bioprofile.com\/biomarkers\/cystatine-c\/#biomarker\",\"name\":\"Cystatine C\",\"alternateName\":[\"Cystatin C\"]}]}<\/script>\n\n\n\n<section class=\"wp-block-group bp-adv bp-biomarker bp-biomarker--page is-layout-flow wp-block-group-is-layout-flow\">\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity bp-adv-rule\"\/>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--hero is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-bm-crumbs wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/\">Inicio<\/a> \u203a <a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/\">Biomarcadores<\/a> \u203a <span>Cistatina C<\/span><\/p>\n\n\n\n<h1 class=\"wp-block-heading bp-adv-h1\">Cistatina C: qu\u00e9 dice tu valor sobre tus ri\u00f1ones<\/h1>\n\n\n\n<p class=\"bp-adv-standfirst wp-block-paragraph\">En un estudio amplio, los investigadores analizaron a personas cuya filtraci\u00f3n renal, estimada a partir de la creatinina, era de 45 a 59 ml por minuto por 1,73 m\u00b2. Un c\u00e1lculo con la creatinina y la cistatina C juntas reclasific\u00f3 correctamente al 16,9% de ellas con una filtraci\u00f3n de 60 ml o m\u00e1s por minuto.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"bp-adv-lede wp-block-paragraph\">En esta p\u00e1gina ver\u00e1s qu\u00e9 es la cistatina C, qu\u00e9 dicen las gu\u00edas sobre un valor demasiado bajo o demasiado alto, qu\u00e9 influye en tu valor y qu\u00e9 otros valores conviene mirar a su lado.<\/p>\n\n\n\n<p class=\"bp-bm-names wp-block-paragraph\">Tambi\u00e9n conocida como: cystatin C, cistatina C s\u00e9rica. En el laboratorio: CYSTAT.<\/p>\n\n\n\n<p class=\"bp-adv-byline wp-block-paragraph\">Actualizado el 10 de octubre de 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group bp-bm-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-inhoud\">En esta p\u00e1gina<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li><a href=\"#bp-in-het-kort\">En resumen<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-is-cystatine-c\">\u00bfQu\u00e9 es la cistatina C?<\/a><\/li>\n\n\n<li><a href=\"#bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa la cistatina C<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu valor de cistatina C<\/a><\/li>\n\n\n<li><a href=\"#bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu cistatina C<\/a><\/li>\n\n\n<li><a href=\"#bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden la cistatina C<\/a><\/li>\n\n\n<li><a href=\"#bp-waarden-die-erbij-horen\">Valores relacionados<\/a><\/li>\n\n\n<li><a href=\"#bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/a><\/li>\n\n\n<li><a href=\"#bp-bronnen\">Fuentes<\/a><\/li>\n\n<\/ul>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-in-het-kort\">En resumen<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>La cistatina C es un marcador de filtraci\u00f3n en tu sangre con el que los m\u00e9dicos estiman lo bien que filtran tus ri\u00f1ones.<sup>[1]<\/sup><\/li>\n\n\n<li>La estimaci\u00f3n basada solo en la creatinina se usa mucho, pero no es precisa, y la cistatina C es una alternativa.<sup>[1]<\/sup><\/li>\n\n\n<li>En un estudio amplio, la creatinina y la cistatina C juntas dieron una estimaci\u00f3n mejor que cada una por separado.<sup>[1]<\/sup><\/li>\n\n\n<li>Seg\u00fan los investigadores, esa combinaci\u00f3n puede ser \u00fatil como prueba de confirmaci\u00f3n en una enfermedad renal de larga duraci\u00f3n.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-is-cystatine-c\">\u00bfQu\u00e9 es la cistatina C?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La cistatina C es un marcador de filtraci\u00f3n. Los m\u00e9dicos la usan para estimar la velocidad de filtraci\u00f3n de tus ri\u00f1ones, en ingl\u00e9s la glomerular filtration rate (GFR). Esa velocidad se expresa en ml por minuto por 1,73 m\u00b2 de superficie corporal.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Los investigadores crearon f\u00f3rmulas de c\u00e1lculo solo con cistatina C y con cistatina C junto con creatinina. Lo hicieron con datos de 5352 participantes de 13 estudios. Despu\u00e9s pusieron a prueba las f\u00f3rmulas en 1119 participantes de otros 5 estudios, a quienes se les hab\u00eda medido la filtraci\u00f3n de verdad.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarom-het-ertoe-doet\">Por qu\u00e9 importa la cistatina C<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Las estimaciones de la filtraci\u00f3n basadas en la creatinina se usan de forma habitual. Sin embargo, no son precisas. Por eso, una enfermedad renal de larga duraci\u00f3n puede diagnosticarse con demasiada frecuencia.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Con la creatinina y la cistatina C juntas, la estimaci\u00f3n se acerc\u00f3 m\u00e1s a menudo a la filtraci\u00f3n medida. El porcentaje de estimaciones que se desviaban m\u00e1s de un 30% del valor medido fue del 8,5%, frente al 12,8% con solo creatinina y al 14,1% con solo cistatina C.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En personas con una filtraci\u00f3n estimada a partir de la creatinina de 45 a 74 ml por minuto por 1,73 m\u00b2, la combinaci\u00f3n clasific\u00f3 mejor la filtraci\u00f3n medida como inferior a 60 o como 60 o superior. Por eso, los investigadores ven la combinaci\u00f3n como una prueba de confirmaci\u00f3n que puede ser \u00fatil.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-je-waarde-zegt\">Qu\u00e9 dice tu valor de cistatina C<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">La directriz del laboratorio<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">El laboratorio con el que trabaja BioProfile, Labplusarts, usa para la cistatina C un rango de referencia de 0,64 a 1,12 mg\/L. Un valor dentro de esos l\u00edmites, el laboratorio lo considera normal.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">El rango de referencia de Labplusarts<\/h3>\n\n\n\n<figure class=\"wp-block-table bp-bm-table\"><table><thead><tr><th>Valor<\/th><th>Qu\u00e9 puede significar<\/th><th>Para qui\u00e9n<\/th><\/tr><\/thead><tbody><tr><td>0,64 a 1,12 mg\/L<sup>[2]<\/sup><\/td><td>El laboratorio considera normal este valor<\/td><td>Qui\u00e9n encarga la prueba CYSTAT a este laboratorio<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"bp-bm-caption wp-block-paragraph\">Fuente: rango de referencia del laboratorio Labplusarts para la cistatina C (CYSTAT), lista del 24 de septiembre de 2026. Las fuentes de esta p\u00e1gina no indican l\u00edmites propios para la cistatina C en s\u00ed.<sup>[2]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cistatina C demasiado alta<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En la fuente, la cistatina C sirve para estimar lo bien que filtran tus ri\u00f1ones. Por eso, un valor alto no se lee de forma aislada. Junto con la creatinina, la cistatina C dio en el estudio la estimaci\u00f3n m\u00e1s precisa, y esa combinaci\u00f3n puede ayudar a confirmar una enfermedad renal de larga duraci\u00f3n. Un m\u00e9dico valora qu\u00e9 otros valores hay que tener en cuenta.<sup>[1]<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioProfile est\u00e1 trabajando en sus propias zonas para cada valor, de riesgo a \u00f3ptimo. Un m\u00e9dico valora esas zonas antes de que aparezcan en tu resultado.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-wat-het-beinvloedt\">Qu\u00e9 influye en tu cistatina C<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">C\u00f3mo de bien filtran tus ri\u00f1ones<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">La cistatina C es un marcador de filtraci\u00f3n. Su valor est\u00e1 relacionado con la filtraci\u00f3n de tus ri\u00f1ones, y por eso sirve para estimarla.<sup>[1]<\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">El m\u00e9todo de medici\u00f3n del laboratorio<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En el estudio, las mediciones de cistatina C y de creatinina eran trazables a materiales de referencia primarios. As\u00ed, los resultados estaban vinculados a un est\u00e1ndar fijo, algo que importa cuando los usas en una f\u00f3rmula de c\u00e1lculo.<sup>[1]<\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-welke-pakketten\">Qu\u00e9 paquetes de BioProfile miden la cistatina C<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La cistatina C est\u00e1 incluida en BioProfile 150.<sup>[3]<\/sup><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\">Ver los paquetes<\/a><\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-waarden-die-erbij-horen\">Valores que la acompa\u00f1an<\/h2>\n\n\n\n<ul class=\"wp-block-list bp-bm-related\">\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/egfr\/\">eGFR<\/a>: la filtraci\u00f3n estimada de tus ri\u00f1ones, que se puede calcular con la cistatina C, con la creatinina o con las dos juntas.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/creatinina\/\">Creatinina<\/a>: el otro marcador de filtraci\u00f3n, que junto con la cistatina C dio la estimaci\u00f3n m\u00e1s precisa en un estudio.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/urea\/\">Urea<\/a>: un valor adicional de la sangre, junto a los marcadores de filtraci\u00f3n creatinina y cistatina C, sobre el que la fuente de esta p\u00e1gina no dice nada.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/proteinas-en-orina\/\">Prote\u00edna (orina)<\/a>: una mirada a tu orina, mientras que la cistatina C en sangre solo estima la filtraci\u00f3n de tus ri\u00f1ones.<sup>[1]<\/sup><\/li>\n\n\n<li><a href=\"https:\/\/bioprofile.com\/es\/biomarkers\/sangre-en-orina\/\">Sangre oculta (orina)<\/a>: una segunda mirada a tu orina, junto a la estimaci\u00f3n de la filtraci\u00f3n que da la cistatina C en sangre.<sup>[1]<\/sup><\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-hoe-gemaakt\">C\u00f3mo se ha hecho esta p\u00e1gina<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La redacci\u00f3n de BioProfile escribi\u00f3 esta p\u00e1gina el 10 de octubre de 2026 a partir de las fuentes que aparecen abajo, que le\u00edmos el 10 de octubre de 2026. Cada cifra de esta p\u00e1gina est\u00e1 en una de esas fuentes, con el n\u00famero de esa fuente al lado. Una persona experta todav\u00eda va a revisar esta p\u00e1gina; despu\u00e9s de esa revisi\u00f3n, su nombre y la fecha de la revisi\u00f3n aparecer\u00e1n arriba. Esta p\u00e1gina explica y no da un diagn\u00f3stico. Habla de un valor alterado con tu m\u00e9dico de cabecera.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-adv-sec bp-adv-sec--disclosure is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bp-bronnen\">Fuentes<\/h2>\n\n\n\n<ol class=\"wp-block-list bp-adv-srclist bp-bm-src\">\n\n<li>Inker LA, Schmid CH, Tighiouart H, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012;367(1):20-9. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22762315\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/22762315\/<\/a><\/li>\n\n\n<li>Labplusarts, el laboratorio con el que trabaja BioProfile: valor de referencia de la determinaci\u00f3n de cistatina C (CYSTAT), 0,64 a 1,12 mg\/L. Lista del 24 de septiembre de 2026.<\/li>\n\n\n<li>BioProfile, los paquetes del an\u00e1lisis de sangre y los valores de cada paquete. <a href=\"https:\/\/bioprofile.com\/es\/analisis-de-sangre\/\" target=\"_blank\" rel=\"noopener\">https:\/\/bioprofile.com\/es\/analisis-de-sangre\/<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n<\/section>\n\n","protected":false},"excerpt":{"rendered":"<p>Inicio \u203a Biomarcadores \u203a Cistatina C Cistatina C: qu\u00e9 dice tu valor sobre tus ri\u00f1ones En un estudio amplio, los investigadores analizaron a personas cuya filtraci\u00f3n renal, estimada a partir de la creatinina, era de 45 a 59 ml por minuto por 1,73 m\u00b2. Un c\u00e1lculo con la creatinina y la cistatina C juntas reclasific\u00f3 [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":6604,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_yoast_wpseo_title":"Cistatina C: qu\u00e9 dice tu valor | BioProfile","_yoast_wpseo_metadesc":"\u00bfQu\u00e9 es la cistatina C, c\u00f3mo ayuda a estimar la filtraci\u00f3n de tus ri\u00f1ones y qu\u00e9 valores conviene mirar a su lado? 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