{"id":8202,"date":"2026-10-13T15:44:00","date_gmt":"2026-10-13T15:44:00","guid":{"rendered":"https:\/\/bioprofile.com\/?p=8202"},"modified":"2026-10-14T00:37:26","modified_gmt":"2026-10-14T00:37:26","slug":"sintomas-falta-vitamina-b12","status":"publish","type":"post","link":"https:\/\/bioprofile.com\/es\/sintomas-falta-vitamina-b12\/","title":{"rendered":"S\u00edntomas de falta de vitamina B12: lo que notas, qui\u00e9n tiene m\u00e1s riesgo y cu\u00e1ndo ir al m\u00e9dico de cabecera"},"content":{"rendered":"\n<article class=\"wp-block-group bp-blog is-layout-flow wp-block-group-is-layout-flow\">\n\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n<link rel=\"stylesheet\" href=\"https:\/\/fonts.googleapis.com\/css2?family=Poppins:wght@300;400;500;600;700&#038;display=swap\">\n<style id=\"bp-blog-design\">\n.bp-blog {\n  --bp-ink: #212527; --bp-teal: #005859; --bp-teal-deep: #006B62; --bp-emerald: #228A62;\n  --bp-green: #7CA74D; --bp-lime: #B7CB33; --bp-lime-soft: #B7CB3329; --bp-green-aa: #4F6B28;\n  --bp-beige: #EDEAE5; --bp-sand: #DBD4CB; --bp-pale-teal: #D9E6E6; --bp-white: #FFFFFF;\n  --bp-foot: #6b6b6b;\n  --bp-font: 'Poppins','Segoe UI',Arial,sans-serif;\n  --bp-fs-h1: 40px; --bp-fs-h2: 29px; --bp-fs-h3: 21px; --bp-fs-body: 17px;\n  --bp-fs-lead: 19px; --bp-fs-small: 14px; --bp-fs-foot: 13px; --bp-fs-btn: 17px;\n  --bp-lh-body: 1.75;\n  --bp-s-2: 8px; --bp-s-3: 12px; --bp-s-4: 16px; --bp-s-5: 24px; --bp-s-6: 32px;\n  --bp-s-7: 44px; --bp-s-8: 72px;\n  --bp-measure: 875px; --bp-prose: 875px; --bp-side: 40px; --bp-portrait: 132px;\n  --bp-radius-card: 20px; --bp-radius-btn: 10px; --bp-radius-chip: 999px;\n  --bp-shadow: 0 10px 30px rgba(0,88,89,0.10); --bp-shadow-soft: 0 2px 10px rgba(0,88,89,0.06);\n  font-family: var(--bp-font); font-size: var(--bp-fs-body); line-height: var(--bp-lh-body);\n  color: var(--bp-ink); background: var(--bp-white); -webkit-font-smoothing: antialiased;\n}\n.bp-blog, .bp-blog * { box-sizing: border-box; }\n.bp-blog p, .bp-blog li, .bp-blog h1, .bp-blog h2, .bp-blog h3, .bp-blog a, .bp-blog td,\n.bp-blog th, .bp-blog cite { overflow-wrap: break-word; min-width: 0; }\n.bp-blog h1, .bp-blog h2, .bp-blog h3 { text-wrap: balance; }\n.bp-blog p, .bp-blog li { text-wrap: pretty; }\n\/* WordPress core's flow layout puts 24px above every child after the first; inside\n   a grid or a flex row that is a misalignment (measured on the scan pages 2026-08-21) *\/\n.bp-blog .bp-blog-author > *, .bp-blog .bp-blog-related > *, .bp-blog .bp-blog-verify > * { margin-block: 0; }\n\n\/* --- sections: one column, the article measure, the section rhythm ------------ *\/\n.bp-blog-sec { position: relative; background: var(--bp-white); margin-block: 0;\n  padding-block: var(--bp-s-7);\n  padding-inline: max(var(--bp-side), calc((100% - var(--bp-measure)) \/ 2)); }\n.bp-blog-sec > *:last-child { margin-block-end: 0; }\n.bp-blog-sec > p, .bp-blog-sec > ul, .bp-blog-sec > ol, .bp-blog-sec > .wp-block-quote,\n.bp-blog-sec > .bp-blog-faq-item, .bp-blog-sec > .bp-blog-takeaways, .bp-blog-sec > .bp-blog-toc,\n.bp-blog-sec > .bp-blog-refs, .bp-blog-sec > .bp-blog-srclead { max-width: var(--bp-prose); }\n.bp-blog-sec--head { padding-block: var(--bp-s-7) 0; }\n.bp-blog-sec--body { padding-block: var(--bp-s-6) var(--bp-s-7); }\n.bp-blog-sec--beige { background: var(--bp-beige); }\n.bp-blog-sec--wash { background: linear-gradient(180deg, #B7CB331A 0%, #B7CB330D 100%), #FFFFFF; }\n.bp-blog-sec--tight { padding-block: var(--bp-s-6); }\n\/* A COLOURED SECTION IS A PANEL, so it carries the panel radius. 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Es importante, porque algunos grupos corren claramente m\u00e1s riesgo.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup> <a href=\"https:\/\/bioprofile.com\/es\/escaner-test-de-estilo-de-vida\/\">El test de estilo de vida de BioProfile<\/a> te da una idea de d\u00f3nde est\u00e1s hoy en tu forma de vivir y de envejecer. No es un diagn\u00f3stico. Es informaci\u00f3n para que veas d\u00f3nde est\u00e1s hoy y para ayudarte a tomar mejores decisiones sobre tu alimentaci\u00f3n y tu estilo de vida. El test no mide tu nivel de B12 ni se\u00f1ala ninguna causa. Eso solo puede valorarlo un m\u00e9dico.<\/p>\n\n\n\n<div class=\"wp-block-group bp-blog-verify bp-blog-verify--top is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas.webp\" alt=\"Retrato de Justinas \u0160likas\" class=\"wp-image-5796\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas.webp 800w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas-240x300.webp 240w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/09\/rt-portret-justinas-slikas-768x960.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"bp-blog-verify-name wp-block-paragraph\">Verificado por <a href=\"https:\/\/bioprofile.com\/experts\/justinas-slikas\/\">Justinas \u0160likas, PhD<\/a><\/p>\n\n\n\n<p class=\"bp-blog-verify-cred wp-block-paragraph\">Doctorado en qu\u00edmica por la University of Edinburgh<\/p>\n\n\n\n<p class=\"bp-blog-verify-date wp-block-paragraph\">Revisado: 4 oct. 2026<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-takeaways is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">En resumen<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n\n<li>Los s\u00edntomas de la falta de vitamina B12 se dividen en dos grupos: molestias nerviosas como hormigueo en manos y pies, y el cansancio, la falta de aire y los mareos propios de la anemia.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/li>\n\n\n<li>La causa m\u00e1s frecuente de una falta grave es una enfermedad del est\u00f3mago que se ve sobre todo en personas mayores. Tomar metformina o protectores de est\u00f3mago durante mucho tiempo tambi\u00e9n va unido a una B12 m\u00e1s baja.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a>,<a href=\"#bronnen\">3<\/a>,<a href=\"#bronnen\">4<\/a><\/sup><\/li>\n\n\n<li>El esc\u00e1ner de estilo de vida te ayuda a conocerte mejor en c\u00f3mo vives y c\u00f3mo envejeces. El esc\u00e1ner no mide tu valor de B12 y no es un diagn\u00f3stico.<\/li>\n\n<\/ul>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-toc is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-toclabel wp-block-paragraph\">Contenido<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n\n<li><a href=\"#vitamine-b12-tekort-symptomen-wat-je-merkt\">S\u00edntomas de falta de vitamina B12: lo que notas<\/a><\/li>\n\n\n<li><a href=\"#wie-loopt-meer-risico\">Qui\u00e9n tiene m\u00e1s riesgo<\/a><\/li>\n\n\n<li><a href=\"#symptomen-tekort-vitamine-b12-wanneer-naar-de-huisarts\">S\u00edntomas de falta de vitamina B12: cu\u00e1ndo ir al m\u00e9dico de cabecera<\/a><\/li>\n\n\n<li><a href=\"#waar-vitamine-b12-in-zit-en-hoeveel-je-nodig-hebt\">D\u00f3nde est\u00e1 la vitamina B12 y cu\u00e1nta necesitas<\/a><\/li>\n\n\n<li><a href=\"#tabletten-injecties-en-zelf-b12-nemen\">Comprimidos, inyecciones y tomar B12 por tu cuenta<\/a><\/li>\n\n\n<li><a href=\"#wat-de-leefstijlscan-meet-en-wat-niet\">Lo que mide el esc\u00e1ner de estilo de vida y lo que no<\/a><\/li>\n\n\n<li><a href=\"#samengevat\">En resumen<\/a><\/li>\n\n\n<li><a href=\"#veelgestelde-vragen\">Preguntas frecuentes<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"vitamine-b12-tekort-symptomen-wat-je-merkt\">S\u00edntomas de falta de vitamina B12: lo que notas<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Thuisarts menciona dos grupos de molestias. El primero son las molestias nerviosas: hormigueo en manos y pies, menos sensibilidad en los dedos, la sensaci\u00f3n de caminar sobre algod\u00f3n y problemas de equilibrio. El segundo son las molestias de la anemia: cansancio y debilidad, falta de aire al hacer esfuerzo, mareos, el coraz\u00f3n que late r\u00e1pido, dolor de cabeza y pitidos en los o\u00eddos.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup> En un art\u00edculo de revisi\u00f3n cl\u00ednica, el hormigueo o la sensaci\u00f3n de entumecimiento en los dos lados del cuerpo y los problemas para caminar eran los s\u00edntomas nerviosos m\u00e1s frecuentes.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En resumen: los s\u00edntomas de la falta de vitamina B12 pueden aparecer en tus nervios, en tu energ\u00eda o en ambos. El cansancio por s\u00ed solo tiene muchas causas posibles, pero el hormigueo en los dos pies es una se\u00f1al m\u00e1s espec\u00edfica.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"wie-loopt-meer-risico\">Qui\u00e9n tiene m\u00e1s riesgo<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La causa m\u00e1s frecuente de una falta grave es la gastritis autoinmune, tambi\u00e9n llamada anemia perniciosa: el cuerpo ataca la mucosa del est\u00f3mago y la B12 deja de absorberse. En grandes series de estudios, la mediana de edad de las personas afectadas era de 70 a 80 a\u00f1os. Una forma m\u00e1s leve de adelgazamiento de la mucosa del est\u00f3mago, en la que la B12 de los alimentos no se separa de la prote\u00edna, se da en hasta el 20 por ciento de las personas mayores.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As\u00ed que la edad cuenta por s\u00ed sola: un est\u00f3mago mayor puede liberar menos B12 de los alimentos, incluso con una buena alimentaci\u00f3n. Es uno de los cambios m\u00e1s silenciosos que traen los a\u00f1os. Lo que cambia adem\u00e1s, lo puedes leer en <a href=\"https:\/\/bioprofile.com\/es\/envejecer-de-forma-sana-que-cambia-con-los-anos\/\">lo que cambia al hacerte mayor<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Thuisarts menciona tambi\u00e9n estos grupos: las personas que solo comen alimentos de origen vegetal sin productos con B12 a\u00f1adida ni un suplemento, las personas con enfermedades del est\u00f3mago o del intestino como la enfermedad de Crohn y la colitis ulcerosa, las personas que beben mucho alcohol cada d\u00eda y comen mal, quienes toman omeprazol o metformina, y quienes consumen gas de la risa con regularidad.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hay dos medicamentos bien estudiados. En un estudio neerland\u00e9s con 390 personas con diabetes tipo 2, a las que se sigui\u00f3 durante algo m\u00e1s de cuatro a\u00f1os, el valor de B12 al final era m\u00e1s o menos una quinta parte m\u00e1s bajo con metformina que con un placebo. Unas 7 personas m\u00e1s de cada 100 desarrollaron una carencia.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">3<\/a><\/sup> En un gran estudio estadounidense, las personas con carencia de B12 hab\u00edan tomado con m\u00e1s frecuencia un medicamento para reducir el \u00e1cido del est\u00f3mago durante dos a\u00f1os o m\u00e1s (12 por ciento frente a 7 por ciento). La relaci\u00f3n era claramente m\u00e1s fuerte con dosis m\u00e1s altas.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">4<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lo que esto significa para ti: si llevas a\u00f1os tomando uno de estos medicamentos y notas las molestias descritas arriba, es algo que conviene hablar con tu m\u00e9dico de cabecera. No dejes ning\u00fan medicamento por tu cuenta.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En quienes siguen una alimentaci\u00f3n vegetal, una revisi\u00f3n de 40 estudios en adultos vegetarianos encontr\u00f3 que la proporci\u00f3n con d\u00e9ficit iba del 0 al 86,5 por ciento, y los veganos que no tomaban ning\u00fan suplemento corr\u00edan un riesgo especialmente alto.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">5<\/a><\/sup> Dicho de forma sencilla: si comes solo alimentos de origen vegetal y no tomas B12 de productos enriquecidos ni de un suplemento, lo m\u00e1s probable es que acabes con un d\u00e9ficit.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"symptomen-tekort-vitamine-b12-wanneer-naar-de-huisarts\">S\u00edntomas de falta de vitamina B12: cu\u00e1ndo ir al m\u00e9dico de cabecera<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Thuisarts aconseja contactar con tu m\u00e9dico de cabecera si tienes signos de anemia, si tienes molestias nerviosas como menos sensibilidad u hormigueo en los dedos, si solo comes alimentos de origen vegetal y tienes molestias que encajan con ello, o si tienes molestias mientras tomas medicamentos para reducir el \u00e1cido del est\u00f3mago, como el omeprazol, o metformina.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"waar-vitamine-b12-in-zit-en-hoeveel-je-nodig-hebt\">D\u00f3nde est\u00e1 la vitamina B12 y cu\u00e1nta necesitas<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Los adultos necesitan 2,8 microgramos de vitamina B12 al d\u00eda. La B12 est\u00e1 en los productos de origen animal. Por raci\u00f3n, el Voedingscentrum menciona el salm\u00f3n (100 gramos) con 4,0 microgramos, la carne de vacuno (75 gramos) con 1,6, un huevo con 0,8, un vaso de leche (150 ml) con 0,7 y el yogur (150 ml) con 0,6. A las personas veganas se les aconseja tomar productos con B12 a\u00f1adida y un suplemento que se ajuste a la cantidad diaria. La mayor\u00eda de las dem\u00e1s personas no necesitan ning\u00fan suplemento.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">6<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Un estudio neerland\u00e9s en personas mayores encontr\u00f3 que los marcadores de B12 en sangre mejoraban a medida que aumentaba la ingesta, pero se estabilizaban por encima de una ingesta de unos 5 microgramos al d\u00eda.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">7<\/a><\/sup> Esto significa que una alimentaci\u00f3n variada con algunos productos de origen animal cubre en gran parte lo que necesitas. Por encima de ese punto, comer m\u00e1s cambiaba poco los valores en sangre.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"tabletten-injecties-en-zelf-b12-nemen\">Comprimidos, inyecciones y tomar B12 por tu cuenta<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Si se encuentra una carencia, Thuisarts menciona comprimidos de 1000 microgramos (1 miligramo) al d\u00eda durante 3 meses.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup> Los comprimidos en dosis alta funcionan m\u00e1s o menos igual de bien que las inyecciones mensuales para que los valores en sangre y los hallazgos nerviosos vuelvan a la normalidad.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> Una revisi\u00f3n Cochrane de tres estudios peque\u00f1os no encontr\u00f3 ninguna diferencia significativa en los valores en sangre entre comprimidos e inyecciones. La evidencia era de baja calidad, y los comprimidos cuestan menos.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">8<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">No est\u00e1 demostrado que m\u00e1s sea mejor. En una cohorte neerlandesa de 5.571 adultos a los que se sigui\u00f3 durante unos ocho a\u00f1os, las personas con los valores de B12 m\u00e1s altos murieron aproximadamente el doble de veces que las personas con los valores m\u00e1s bajos. Despu\u00e9s de que los investigadores tuvieran en cuenta otros factores, un valor m\u00e1s alto segu\u00eda yendo unido a un riesgo algo mayor. Los investigadores escriben que el motivo se desconoce, y el estudio no muestra que la propia B12 cause da\u00f1o.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">9<\/a><\/sup> Para ti, esto significa que tomar B12 sin motivo no es un extra gratuito. Si tienes molestias, lo primero es hablar con tu m\u00e9dico de cabecera.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"wat-de-leefstijlscan-meet-en-wat-niet\">Lo que mide el escaneo de estilo de vida y lo que no<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">El esc\u00e1ner de estilo de vida se fija en c\u00f3mo vives y c\u00f3mo envejeces, y te da un punto de partida con el que comparar m\u00e1s adelante. El esc\u00e1ner no lee ning\u00fan valor de B12, y el hormigueo o el cansancio pueden tener muchas causas que el esc\u00e1ner no muestra. El esc\u00e1ner no es un diagn\u00f3stico. Si quieres saber qu\u00e9 tiene que ver el estilo de vida con el ritmo al que envejeces, <a href=\"https:\/\/bioprofile.com\/es\/edad-biologica-frente-a-edad-cronologica\/\">edad biol\u00f3gica frente a edad cronol\u00f3gica<\/a> te explica la diferencia.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"samengevat\">En resumen<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Los s\u00edntomas de falta de vitamina B12 son molestias en los nervios y el cansancio y la falta de aire propios de la anemia. Las personas mayores, quienes comen solo vegetales sin B12, las personas con enfermedades del est\u00f3mago o del intestino y quienes toman metformina o protectores de est\u00f3mago durante mucho tiempo tienen m\u00e1s riesgo. Los productos de origen animal te aportan la B12. La mayor\u00eda de la gente toma suficiente, pero los veganos necesitan un suplemento. Si tienes molestias, el lugar al que acudir es tu m\u00e9dico de cabecera. El esc\u00e1ner de estilo de vida te da una visi\u00f3n de c\u00f3mo vives y c\u00f3mo envejeces.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-cta is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Descubre d\u00f3nde est\u00e1s<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">El esc\u00e1ner de estilo de vida te da un punto de partida sobre c\u00f3mo vives y c\u00f3mo envejeces. En la p\u00e1gina del esc\u00e1ner encontrar\u00e1s lo que mide y en qu\u00e9 se basa.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/bioprofile.com\/es\/escaner-test-de-estilo-de-vida\/\">Empieza el chequeo de estilo de vida<\/a><\/div>\n\n<\/div>\n\n\n\n<p class=\"bp-blog-ctamicro wp-block-paragraph\">Gratis, unos 3 minutos. Un an\u00e1lisis de tus respuestas, nunca un diagn\u00f3stico. <a href=\"https:\/\/bioprofile.com\/es\/chequeos-de-salud\/\">Todos los esc\u00e1neres de salud<\/a><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--wash is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"veelgestelde-vragen\">Preguntas frecuentes<\/h2>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">\u00bfC\u00f3mo subo r\u00e1pido mi B12?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Si tienes una carencia o no, lo valora un m\u00e9dico de cabecera. Thuisarts menciona comprimidos de 1000 microgramos al d\u00eda durante 3 meses.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup> Una revisi\u00f3n Cochrane encontr\u00f3 que los comprimidos en esa dosis sub\u00edan los valores en sangre m\u00e1s o menos igual de bien que las inyecciones, aunque la evidencia era de baja calidad.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">8<\/a><\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">\u00bfQu\u00e9 enfermedad causa una carencia de B12?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">La causa m\u00e1s frecuente de una falta grave es la gastritis autoinmune, tambi\u00e9n llamada anemia perniciosa.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">2<\/a><\/sup> Las enfermedades intestinales, como la enfermedad de Crohn y la colitis ulcerosa, tambi\u00e9n aumentan el riesgo.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">\u00bfQu\u00e9 alimentos tienen m\u00e1s vitamina B12?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En los productos de origen animal. Por raci\u00f3n, el Voedingscentrum menciona el salm\u00f3n (100 gramos), con 4,0 microgramos, bastante m\u00e1s que los 2,8 microgramos que un adulto necesita al d\u00eda. La carne de ternera, los huevos, la leche y el yogur contienen menos.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">6<\/a><\/sup><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-faq-item is-layout-flow wp-block-group-is-layout-flow\">\n\n<h3 class=\"wp-block-heading\">\u00bfPuedes empezar a tomar B12 por tu cuenta?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">La mayor\u00eda de la gente no necesita un suplemento. Los veganos son la excepci\u00f3n y se les aconseja tomar uno.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">6<\/a><\/sup> Si tienes molestias, Thuisarts aconseja contactar primero con tu m\u00e9dico de cabecera.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">1<\/a><\/sup> No est\u00e1 demostrado que m\u00e1s sea mejor: en una cohorte neerlandesa, las personas con valores de B12 en sangre m\u00e1s altos murieron algo m\u00e1s a menudo. Los investigadores no pueden decir por qu\u00e9.\u2060<sup class=\"bp-blog-sup\"><a href=\"#bronnen\">9<\/a><\/sup><\/p>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--beige bp-blog-sec--tight is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\" id=\"bronnen\">Fuentes<\/h2>\n\n\n\n<p class=\"bp-blog-srclead wp-block-paragraph\">Todas las fuentes de abajo se comprobaron el d\u00eda en que se public\u00f3 este art\u00edculo. La numeraci\u00f3n sigue el texto.<\/p>\n\n\n\n<ol class=\"wp-block-list bp-blog-refs\">\n\n<li>NHG. Ik heb misschien te weinig vitamine B12. Thuisarts.nl. <a href=\"https:\/\/www.thuisarts.nl\/vitamine-b12\/ik-heb-misschien-te-weinig-vitamine-b12\">thuisarts.nl<\/a><\/li>\n\n\n<li>Stabler SP. Clinical practice. Vitamin B12 deficiency. New England Journal of Medicine, 2013;368:149-160. <a href=\"https:\/\/doi.org\/10.1056\/NEJMcp1113996\">doi.org\/10.1056\/NEJMcp1113996<\/a><\/li>\n\n\n<li>de Jager J, Kooy A, Lehert P, et al. Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial. BMJ, 2010. Mean B12 19% lower with metformin than with placebo (95% CI -24% to -14%; P&lt;0.001); risk of deficiency 7.2 percentage points higher (number needed to harm 13.8 per 4.3 years). <a href=\"https:\/\/doi.org\/10.1136\/bmj.c2181\">doi.org\/10.1136\/bmj.c2181<\/a><\/li>\n\n\n<li>Lam JR, Schneider JL, Zhao W, Corley DA. Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency. JAMA, 2013. Two years or more of a proton pump inhibitor: OR 1.65 (95% CI 1.58 to 1.73); more than 1.5 pills a day: OR 1.95 (95% CI 1.77 to 2.15). <a href=\"https:\/\/doi.org\/10.1001\/jama.2013.280490\">doi.org\/10.1001\/jama.2013.280490<\/a><\/li>\n\n\n<li>Pawlak R, Lester SE, Babatunde T. The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature. European Journal of Clinical Nutrition, 2014. <a href=\"https:\/\/doi.org\/10.1038\/ejcn.2014.46\">doi.org\/10.1038\/ejcn.2014.46<\/a><\/li>\n\n\n<li>Voedingscentrum. Vitamine B12. Encyclopedie, voedingscentrum.nl. <a href=\"https:\/\/www.voedingscentrum.nl\/encyclopedie\/vitamine-b12.aspx\">voedingscentrum.nl<\/a><\/li>\n\n\n<li>van Wijngaarden JP, Dhonukshe-Rutten RAM, Brouwer-Brolsma EM, et al. Vitamin B12 intake and related biomarkers: associations in a Dutch elderly population. Journal of Nutrition, Health y Aging, 2017. <a href=\"https:\/\/doi.org\/10.1007\/s12603-017-0911-6\">doi.org\/10.1007\/s12603-017-0911-6<\/a><\/li>\n\n\n<li>Wang H, Li L, Qin LL, Song Y, Vidal-Alaball J, Liu TH. Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. Cochrane Database of Systematic Reviews, 2018. <a href=\"https:\/\/doi.org\/10.1002\/14651858.CD004655.pub3\">doi.org\/10.1002\/14651858.CD004655.pub3<\/a><\/li>\n\n\n<li>Flores-Guerrero JL, Minovic I, Groothof D, et al. Association of plasma concentration of vitamin B12 with all-cause mortality in the general population in the Netherlands. JAMA Network Open, 2020. After adjustment, HR per 1-SD increase in B12 1.25 (95% CI 1.06 to 1.47; P = .006). <a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.19274\">doi.org\/10.1001\/jamanetworkopen.2019.19274<\/a><\/li>\n\n<\/ol>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--tight is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Lee tambi\u00e9n<\/h2>\n\n\n\n<div class=\"wp-block-group bp-blog-related is-layout-flow wp-block-group-is-layout-flow\">\n\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/envejecer-de-forma-sana-que-cambia-con-los-anos\/\">Envejecer con salud: qu\u00e9 cambia de forma medible con los a\u00f1os, qu\u00e9 pone en primer lugar una cohorte neerlandesa de 30 a\u00f1os y qu\u00e9 mide un esc\u00e1ner de estilo de vida<\/a><\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/bioprofile.com\/es\/edad-biologica-frente-a-edad-cronologica\/\">Edad biol\u00f3gica frente a edad cronol\u00f3gica: qu\u00e9 miden los test de edad biol\u00f3gica, con qu\u00e9 se relacionan las cifras y qu\u00e9 muestra un test de estilo de vida<\/a><\/p>\n\n<\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--tight is-layout-flow wp-block-group-is-layout-flow\">\n\n<h2 class=\"wp-block-heading\">Escrito por<\/h2>\n\n\n\n<div class=\"wp-block-group bp-blog-author is-layout-flow wp-block-group-is-layout-flow\">\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"320\" height=\"320\" src=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg\" alt=\"Jesse van der Velde\" class=\"wp-image-4815\" srcset=\"https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320.jpg 320w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-300x300.jpg 300w, https:\/\/bioprofile.com\/wp-content\/uploads\/2026\/07\/author-jesse-round-320-150x150.jpg 150w\" sizes=\"(max-width: 320px) 100vw, 320px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-group bp-blog-authorid is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorrole wp-block-paragraph\">Fundador de BioProfile<\/p>\n\n\n\n<p class=\"bp-blog-authorname wp-block-paragraph\">Jesse van der Velde<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-authorbody is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorbio wp-block-paragraph\">Jesse van der Velde gu\u00eda desde 2006 a personas hacia un cuerpo nuevo y una salud \u00f3ptima, y ha escrito o coescrito quince libros sobre alimentaci\u00f3n y salud. Para siempre joven (2012) y Superfoodrecepten (2013) llegaron los dos al n\u00famero 1 en Nederland.<\/p>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-authormeta is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-authorbio wp-block-paragraph\"><a href=\"https:\/\/nl.linkedin.com\/in\/jessevdv\">LinkedIn<\/a><\/p>\n\n\n\n<p class=\"bp-blog-dates wp-block-paragraph\">Publicado el 13 de octubre de 2026 \u00b7 \u00daltima actualizaci\u00f3n: 13 de octubre de 2026<\/p>\n\n<\/div>\n\n<\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-group bp-blog-sec bp-blog-sec--foot is-layout-flow wp-block-group-is-layout-flow\">\n\n<p class=\"bp-blog-legal wp-block-paragraph\">BioProfile analiza tu estado de salud para orientarte a ti y a tu coach. No hace un diagn\u00f3stico, eso solo lo puede hacer un m\u00e9dico. Est\u00e1 construido sobre cuestionarios de salud validados; la puntuaci\u00f3n combinada de BioProfile todav\u00eda no es en s\u00ed misma un instrumento cl\u00ednico validado. Tus respuestas siguen siendo privadas (RGPD).<\/p>\n\n<\/div>\n\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Hormigueo en los pies, cansancio, falta de aire: s\u00edntomas de falta de vitamina B12, qui\u00e9n tiene m\u00e1s riesgo, d\u00f3nde est\u00e1 la B12 y cu\u00e1ndo ir al m\u00e9dico de cabecera.<\/p>\n","protected":false},"author":18,"featured_media":7785,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_meta-robots-noindex":"2","_yoast_wpseo_opengraph-image":"","_yoast_wpseo_opengraph-image-id":"","_yoast_wpseo_twitter-image":"","_yoast_wpseo_twitter-image-id":"","inline_featured_image":false,"footnotes":""},"categories":[93],"tags":[],"class_list":["post-8202","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthy-aging-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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